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PDB: 80 件

2K0X
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The actinorhodin holo acyl carrier protein from S. coelicolor
分子名称: 4'-PHOSPHOPANTETHEINE, Actinorhodin polyketide synthase acyl carrier protein
著者Crump, M.P, Evans, S.E, Williams, C.
登録日2008-02-15
公開日2008-09-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein.
Chembiochem, 9, 2008
1ZUJ
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The crystal structure of the Lactococcus lactis MG1363 DpsA protein
分子名称: hypothetical protein Llacc01001955
著者Stillman, T.J, Upadhyay, M, Norte, V.A, Sedelnikova, S.E, Carradus, M, Tzokov, S, Bullough, P.A, Shearman, C.A, Gasson, M.J, Williams, C.H, Artymiuk, P.J, Green, J.
登録日2005-05-31
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structures of Lactococcus lactis MG1363 Dps proteins reveal the presence of an N-terminal helix that is required for DNA binding.
Mol.Microbiol., 57, 2005
1ZS3
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The crystal structure of the Lactococcus lactis MG1363 DpsB protein
分子名称: Lactococcus lactis MG1363 DpsA
著者Stillman, T.J, Upadhyay, M, Norte, V.A, Sedelnikova, S.E, Carradus, M, Tzokov, S, Bullough, P.A, Shearman, C.A, Gasson, M.J, Williams, C.H, Artymiuk, P.J, Green, J.
登録日2005-05-23
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structures of Lactococcus lactis MG1363 Dps proteins reveal the presence of an N-terminal helix that is required for DNA binding.
Mol.Microbiol., 57, 2005
2PNG
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Type I rat fatty acid synthase acyl carrier protein (ACP) domain
分子名称: Fatty acid synthase (EC 2.3.1.85)
著者Ploskon, E.A, Arthur, C.J, Evans, S.E, Williams, C, Crosby, J, Crump, M.P.
登録日2007-04-24
公開日2007-06-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A Mammalian type I Fatty Acid synthase acyl carrier protein domain does not sequester acyl chains.
J.Biol.Chem., 283, 2008
6GWX
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Stabilising and Understanding a Miniprotein by Rational Design.
分子名称: Optimised PPa-TYR
著者Porter Goff, K.L, Williams, C, Baker, E.G, Nicol, D, Samphire, J.L, Zieleniewski, F.L, Crump, M.P, Woolfson, D.N.
登録日2018-06-26
公開日2019-07-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Stabilizing and Understanding a Miniprotein by Rational Redesign.
Biochemistry, 58, 2019
2CNR
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Structural studies on the interaction of ScFAS ACP with ACPS
分子名称: ACYL CARRIER PROTEIN
著者Pottage, K, Williams, C, Crump, M.P.
登録日2006-05-23
公開日2007-06-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Malonyl Coa-Acp Transacylase Binding of Streptomyces Coelicolor Fatty Acid Synthase Acyl Carrier Protein.
Acs Chem.Biol., 4, 2009
2B4K
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Acetobacter turbidans alpha-amino acid ester hydrolase complexed with phenylglycine
分子名称: Alpha-amino acid ester hydrolase, D-PHENYLGLYCINE, GLYCEROL
著者Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Williams, C, Wybenga, G, Janssen, D.B, Dijkstra, B.W.
登録日2005-09-26
公開日2005-12-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme.
J.Biol.Chem., 281, 2006
2MVV
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Solution Structure of the 5-phenyl-3-oxo-pentyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3-oxo-5-phenylpentyl)sulfanyl]ethyl}-beta-alaninamide
著者Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T.J, Willis, C.L, Crump, M.P.
登録日2014-10-15
公開日2015-10-21
実験手法SOLUTION NMR
主引用文献ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
2MVU
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Solution Structure of the 3,7-dioxo-octyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3,7-dioxooctyl)sulfanyl]ethyl}-beta-alaninamide
著者Dong, X, Bailey, C, Williams, C, Crosby, J, Simpson, T.J, Willis, C.L, Crump, M.P.
登録日2014-10-15
公開日2015-10-21
実験手法SOLUTION NMR
主引用文献ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
2L22
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Mupirocin didomain ACP
分子名称: Mupirocin didomain Acyl Carrier Protein
著者Dong, X, Williams, C, Crump, M.P, Wattana-amorn, P.
登録日2010-08-10
公開日2012-02-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A conserved motif flags acyl carrier proteins for beta-branching in polyketide synthesis.
Nat.Chem.Biol., 9, 2013
2JIY
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PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M149 REPLACED WITH TRP (CHAIN M, AM149W)
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
著者Fyfe, P.K, Potter, J.A, Cheng, J, Williams, C.M, Watson, A.J, Jones, M.R.
登録日2007-07-03
公開日2007-09-04
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Responses to Cavity-Creating Mutations in an Integral Membrane Protein.
Biochemistry, 46, 2007
2JJ0
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PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M248 REPLACED WITH TRP (CHAIN M, AM248W)
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
著者Fyfe, P.K, Potter, J.A, Cheng, J, Williams, C.M, Watson, A.J, Jones, M.R.
登録日2007-07-03
公開日2007-09-04
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Responses to Cavity-Creating Mutations in an Integral Membrane Protein.
Biochemistry, 46, 2007
2KGD
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NMR Solution Structures of 3-oxo-butyl-ACP, an intermediate mimic from the actinorhodin polyketide synthase in Streptomyces coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(3-oxobutyl)sulfanyl]ethyl}-beta-alaninamide
著者Crump, M.P, Evans, S.E, Williams, C.
登録日2009-03-08
公開日2009-04-14
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KG8
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NMR Solution Structures of malonyl ACP from the actinorhodin polyketide synthase in Streptomyces coelicolor
分子名称: 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid, Actinorhodin polyketide synthase acyl carrier protein
著者Crump, M.P, Evans, S.E, Williams, C, Eliza, P.
登録日2009-03-06
公開日2009-04-14
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGA
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NMR Solution Structures of hexanoyl ACP (a non natural intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate
著者Crump, M.P, Evans, S.E, Williams, C.
登録日2009-03-07
公開日2009-04-14
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KG9
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NMR Solution Structures of butyryl-ACP (a non-polar, non pathway intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein, THIOBUTYRIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER
著者Crump, M.P, Evans, S.E, Williams, C.
登録日2009-03-07
公開日2009-04-14
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGE
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NMR Solution Structures of 3,5-dioxohexyl ACP (a triketide mimic) from the actinorhodin polyketide synthase in Streptomyces coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein, N-{2-[(3,5-dioxohexyl)sulfanyl]ethyl}-N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide
著者Crump, M.P, Evans, S.E, Williams, C.
登録日2009-03-08
公開日2009-04-14
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2KGC
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NMR Solution Structures of octanoyl ACP (a non-natural intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor
分子名称: Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate
著者Crump, M.P, Evans, S.E, Williams, C.
登録日2009-03-08
公開日2009-04-14
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
J.Mol.Biol., 389, 2009
2XQ1
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Crystal structure of peroxisomal catalase from the yeast Hansenula polymorpha
分子名称: PEROXISOMAL CATALASE, PROTOPORPHYRIN IX CONTAINING FE
著者Penya-Soler, E, Vega, M.C, Wilmanns, M, Williams, C.P.
登録日2010-08-31
公開日2011-06-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Features of Peroxisomal Catalase from the Yeast Hansenula Polymorpha
Acta Crystallogr.,Sect.D, 67, 2011
2LLA
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NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor
分子名称: Mannose-6-phosphate/insulin-like growth factor II receptor
著者Strickland, M, Crump, M.P, Williams, C, Rezgui, D, Ellis, R.Z, Hoppe, H, Frago, S, Prince, S.N, Zaccheo, O.J, Forbes, B.E, Jones, E, Hassan, A.Z, Wattana-Amorn, P.
登録日2011-11-05
公開日2012-11-07
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2LP8
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SOLUTION STRUCTURE OF AN APOPTOSIS ACTIVATING PHOTOSWITCHABLE BAK PEPTIDE BOUND to BCL-XL
分子名称: 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1
著者Wysoczanski, P, Mart, R.J, Loveridge, J.E, Williams, C, Whittaker, S.B.-M, Crump, M.P, Allemann, R.K.
登録日2012-02-03
公開日2012-04-18
最終更新日2021-08-18
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L).
J.Am.Chem.Soc., 134, 2012
2LPC
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NMR STRUCTURE of Bcl-XL
分子名称: Bcl-2-like protein 1
著者Wysoczanski, P, Mart, R.J, Loveridge, J.E, Williams, C, Whittaker, S.B.-M, Crump, M.P, Allemann, R.K.
登録日2012-02-09
公開日2012-03-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L).
J.Am.Chem.Soc., 134, 2012
2M68
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NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R in complex with IGF2 (domain 11 structure only)
分子名称: Insulin-like growth factor 2 receptor variant
著者Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S.
登録日2013-03-27
公開日2014-10-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
2JOL
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Average NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei
分子名称: Putative G-nucleotide exchange factor
著者Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S.
登録日2007-03-14
公開日2007-03-27
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
Biochem.J., 411, 2008
2JOK
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NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei
分子名称: Putative G-nucleotide exchange factor
著者Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S.
登録日2007-03-14
公開日2007-09-18
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
Biochem.J., 411, 2008

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