1GUF
 
 | | Enoyl thioester reductase from Candida tropicalis | | 分子名称: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH, B-SPECIFIC] 1, MITOCHONDRIAL, ... | | 著者 | Airenne, T.T, Torkko, J.M, Van Der Plas, S, Sormunen, R.T, Kastaniotis, A.J, Wierenga, R.K, Hiltunen, J.K. | | 登録日 | 2002-01-25 | | 公開日 | 2003-03-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure-Function Analysis of Enoyl Thioester Reductase Involved in Mitochondrial Maintenance
J.Mol.Biol., 327, 2003
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1GU7
 | | Enoyl thioester reductase from Candida tropicalis | | 分子名称: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH, B-SPECIFIC] 1,MITOCHONDRIAL, GLYCEROL, ... | | 著者 | Airenne, T.T, Torkko, J.M, Wierenga, R.K, Hiltunen, J.K. | | 登録日 | 2002-01-24 | | 公開日 | 2003-03-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-Function Analysis of Enoyl Thioester Reductase Involved in Mitochondrial Maintenance
J.Mol.Biol., 327, 2003
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1HNU
 | | CRYSTAL STRUCTURE OF PEROXISOMAL DELTA3-DELTA2-ENOYL-COA ISOMERASE FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | 1,2-ETHANEDIOL, D3,D2-ENOYL COA ISOMERASE ECI1, PERRHENATE | | 著者 | Mursula, A.M, van Aalten, D.M.F, Hiltunen, J.K, Wierenga, R.K. | | 登録日 | 2000-12-08 | | 公開日 | 2001-06-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.
J.Mol.Biol., 309, 2001
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4C2K
 | | Crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Kiema, T.-R, Harijan, R.K, Wierenga, R.K. | | 登録日 | 2013-08-19 | | 公開日 | 2014-09-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities
Acta Crystallogr.,Sect.D, 70, 2014
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4C2J
 | | Crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase in complex with CoA | | 分子名称: | 1,2-ETHANEDIOL, 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL, ... | | 著者 | Kiema, T.-R, Harijan, R.K, Wierenga, R.K. | | 登録日 | 2013-08-19 | | 公開日 | 2014-09-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities
Acta Crystallogr.,Sect.D, 70, 2014
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1HNO
 | | CRYSTAL STRUCTURE OF PEROXISOMAL DELTA3-DELTA2-ENOYL-COA ISOMERASE FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | 1,2-ETHANEDIOL, D3,D2-ENOYL COA ISOMERASE ECI1 | | 著者 | Mursula, A.M, van Aalten, D.M.F, Hiltunen, J.K, Wierenga, R.K. | | 登録日 | 2000-12-08 | | 公開日 | 2001-06-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.
J.Mol.Biol., 309, 2001
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4B3J
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3ZBK
 | | Crystal structure of SCP2 thiolase from Leishmania mexicana: The C123A mutant. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-KETOACYL-COA THIOLASE-LIKE PROTEIN, CHLORIDE ION, ... | | 著者 | Harijan, R.K, Kiema, T.-R, Weiss, M.S, Michels, P.A.M, Wierenga, R.K. | | 登録日 | 2012-11-10 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structures of Scp2-Thiolases of Trypanosomatidae, Human Pathogens Causing Widespread Tropical Diseases: The Importance for Catalysis of the Cysteine of the Unique Hdcf Loop.
Biochem.J., 455, 2013
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1AW2
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1N55
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1AW1
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3ZBN
 | | Crystal structure of SCP2 thiolase from Leishmania mexicana. Complex of the C123A mutant with Coenzyme A. | | 分子名称: | 3-KETOACYL-COA THIOLASE-LIKE PROTEIN, COENZYME A | | 著者 | Harijan, R.K, Kiema, T.-R, Weiss, M.S, Michels, P.A.M, Wierenga, R.K. | | 登録日 | 2012-11-11 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal Structures of Scp2-Thiolases of Trypanosomatidae, Human Pathogens Causing Widespread Tropical Diseases: The Importance for Catalysis of the Cysteine of the Unique Hdcf Loop.
Biochem.J., 455, 2013
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2YIM
 | | The enolisation chemistry of a thioester-dependent racemase: the 1.4 A crystal structure of a complex with a planar reaction intermediate analogue | | 分子名称: | 2-METHYLACETOACETYL COA, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Sharma, S, Bhaumik, P, Venkatesan, R, Hiltunen, J.K, Conzelmann, E, Juffer, A.H, Wierenga, R.K. | | 登録日 | 2011-05-16 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | The Enolization Chemistry of a Thioester-Dependent Racemase: The 1.4 A Crystal Structure of a Reaction Intermediate Complex Characterized by Detailed Qm/Mm Calculations.
J Phys Chem B, 116, 2012
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1TJ7
 | | Structure determination and refinement at 2.44 A resolution of Argininosuccinate lyase from E. coli | | 分子名称: | Argininosuccinate lyase, GLYCEROL, PHOSPHATE ION | | 著者 | Bhaumik, P, Koski, M.K, Bergman, U, Wierenga, R.K. | | 登録日 | 2004-06-03 | | 公開日 | 2004-10-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli.
Acta Crystallogr.,Sect.D, 60, 2004
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2FJ9
 | | High resolution crystal structure of the unliganded human ACBP | | 分子名称: | Acyl-CoA-binding protein, CHLORIDE ION, LEAD (II) ION, ... | | 著者 | Taskinen, J.P, van Aalten, D.M, Knudsen, J, Wierenga, R.K. | | 登録日 | 2006-01-02 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High resolution crystal structures of unliganded and liganded human liver ACBP reveal a new mode of binding for the acyl-CoA ligand.
Proteins, 66, 2006
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1IIG
 | | STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE | | 分子名称: | 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J. | | 登録日 | 2001-04-23 | | 公開日 | 2001-05-11 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
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1TTI
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1PXT
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4BI9
 | | Crystal structure of wild-type SCP2 thiolase from Trypanosoma brucei. | | 分子名称: | 3-KETOACYL-COA THIOLASE, PUTATIVE | | 著者 | Harijan, R.K, Kiema, T.-R, Weiss, M.S, Michels, P.A.M, Wierenga, R.K. | | 登録日 | 2013-04-10 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal Structures of Scp2-Thiolases of Trypanosomatidae, Human Pathogens Causing Widespread Tropical Diseases: The Importance for Catalysis of the Cysteine of the Unique Hdcf Loop.
Biochem.J., 455, 2013
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4BIA
 | | Crystal structure of SCP2 thiolase from Trypanosoma brucei: The C337A mutant. | | 分子名称: | 3-KETOACYL-COA THIOLASE, PUTATIVE | | 著者 | Harijan, R.K, Kiema, T.-R, Weiss, M.S, Michels, P.A.M, Wierenga, R.K. | | 登録日 | 2013-04-10 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structures of Scp2-Thiolases of Trypanosomatidae, Human Pathogens Causing Widespread Tropical Diseases: The Importance for Catalysis of the Cysteine of the Unique Hdcf Loop.
Biochem.J., 455, 2013
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1PJH
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4CQM
 | | Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CARBONYL REDUCTASE FAMILY MEMBER 4, ... | | 著者 | Venkatesan, R, SahTeli, S.K, Awoniyi, L.O, Jiang, G, Prus, P, Kastoniotis, A.J, Hiltunen, J.K, Wierenga, R.K, Chen, Z. | | 登録日 | 2014-02-19 | | 公開日 | 2014-09-10 | | 最終更新日 | 2014-09-17 | | 実験手法 | X-RAY DIFFRACTION (2.339 Å) | | 主引用文献 | Insights Into Mitochondrial Fatty Acid Synthesis from the Structure of Heterotetrameric 3-Ketoacyl-Acp Reductase/3R-Hydroxyacyl-Coa Dehydrogenase.
Nat.Commun., 5, 2014
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4CQL
 | | Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD | | 分子名称: | CARBONYL REDUCTASE FAMILY MEMBER 4, ESTRADIOL 17-BETA-DEHYDROGENASE 8, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Venkatesan, R, Sah-Teli, S.K, Awoniyi, L.O, Jiang, G, Prus, P, Kastaniotis, A.J, Hiltunen, J.K, Wierenga, R.K, Chen, Z. | | 登録日 | 2014-02-19 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Insights Into Mitochondrial Fatty Acid Synthesis from the Structure of Heterotetrameric 3-Ketoacyl-Acp Reductase/3R-Hydroxyacyl-Coa Dehydrogenase.
Nat.Commun., 5, 2014
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2VEM
 | | Structure-based enzyme engineering efforts with an inactive monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties | | 分子名称: | (3-bromo-2-oxo-propoxy)phosphonic acid, GLYCOSOMAL TRIOSEPHOSPHATE ISOMERASE, TERTIARY-BUTYL ALCOHOL | | 著者 | Alahuhta, M, Salin, M, Casteleijn, M.G, Kemmer, C, El-Sayed, I, Augustyns, K, Neubauer, P, Wierenga, R.K. | | 登録日 | 2007-10-25 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-Based Protein Engineering Efforts with a Monomeric Tim Variant: The Importance of a Single Point Mutation for Generating an Active Site with Suitable Binding Properties.
Protein Eng.Des.Sel., 21, 2008
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2VU1
 | | Biosynthetic thiolase from Z. ramigera. Complex of with O-pantheteine- 11-pivalate. | | 分子名称: | ACETYL-COA ACETYLTRANSFERASE, PANTOTHENYL-AMINOETHANOL-11-PIVALIC ACID, SODIUM ION, ... | | 著者 | Kursula, P, Schmitz, W, Wierenga, R.K. | | 登録日 | 2008-05-19 | | 公開日 | 2008-10-28 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme.
FEBS J., 275, 2008
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