8ODW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8odw by Molmil](/molmil-images/mine/8odw) | Crystal structure of LbmA Ox-ACP didomain in complex with NADP and ethyl glycinate from the lobatamide PKS (Gynuella sunshinyii) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Francois, R.M.M, Fraley, A.E, Piel, J, Weissman, K.J, Gruez, A. | Deposit date: | 2023-03-09 | Release date: | 2023-05-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Modular Oxime Formation by a trans-AT Polyketide Synthase. Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
4CA3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ca3 by Molmil](/molmil-images/mine/4ca3) | SOLUTION STRUCTURE OF STREPTOMYCES VIRGINIAE VIRA ACP5B | Descriptor: | HYBRID POLYKETIDE SYNTHASE-NON RIBOSOMAL PEPTIDE SYNTHETASE | Authors: | Davison, J, Dorival, J, Rabeharindranto, M.H, Chagot, B, Gruez, A, Weissman, K.J. | Deposit date: | 2013-10-05 | Release date: | 2014-06-04 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Insights Into the Function of Trans-Acyl Transferase Polyketide Synthases from the Saxs Structure of a Complete Module. Chem.Sci., 2014
|
|
8A7Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a7z by Molmil](/molmil-images/mine/8a7z) | NMR structure of holo-acp | Descriptor: | 4'-PHOSPHOPANTETHEINE, Hybrid polyketide synthase-non ribosomal peptide synthetase | Authors: | Collin, S, Weissman, K.J, Chagot, B, Gruez, A. | Deposit date: | 2022-06-21 | Release date: | 2023-03-22 | Last modified: | 2023-03-29 | Method: | SOLUTION NMR | Cite: | Decrypting the programming of beta-methylation in virginiamycin M biosynthesis. Nat Commun, 14, 2023
|
|
8AIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8aig by Molmil](/molmil-images/mine/8aig) | NMR structure of holo-acp | Descriptor: | 4'-PHOSPHOPANTETHEINE, Hybrid non ribosomal peptide synthetase-polyketide synthase | Authors: | Collin, S, Weissman, K.J, Chagot, B, Gruez, A. | Deposit date: | 2022-07-26 | Release date: | 2023-03-22 | Last modified: | 2023-03-29 | Method: | SOLUTION NMR | Cite: | Decrypting the programming of beta-methylation in virginiamycin M biosynthesis. Nat Commun, 14, 2023
|
|
8ALL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8all by Molmil](/molmil-images/mine/8all) | NMR structure of holo-acp | Descriptor: | 4'-PHOSPHOPANTETHEINE, Hybrid non ribosomal peptide synthetase-polyketide synthase | Authors: | Collin, S, Weissman, K.J, Chagot, B, Gruez, A. | Deposit date: | 2022-08-01 | Release date: | 2023-03-22 | Last modified: | 2023-03-29 | Method: | SOLUTION NMR | Cite: | Decrypting the programming of beta-methylation in virginiamycin M biosynthesis. Nat Commun, 14, 2023
|
|
8RAJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8raj by Molmil](/molmil-images/mine/8raj) | NMR structure of PKS docking domains | Descriptor: | Beta-ketoacyl synthase, Trimethylamine monooxygenase | Authors: | Scat, S, Weissman, K.J, Chagot, B. | Deposit date: | 2023-12-01 | Release date: | 2024-06-05 | Last modified: | 2024-07-17 | Method: | SOLUTION NMR | Cite: | Insights into docking in megasynthases from the investigation of the toblerol trans -AT polyketide synthase: many alpha-helical means to an end. Rsc Chem Biol, 5, 2024
|
|
2JUG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jug by Molmil](/molmil-images/mine/2jug) | |
1PZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pzr by Molmil](/molmil-images/mine/1pzr) | Structure of fused docking domains from the erythromycin polyketide synthase (DEBS), a model for the interaction between DEBS2 and DEBS3: the B domain | Descriptor: | Erythronolide synthase | Authors: | Broadhurst, R.W, Nietlispach, D, Wheatcroft, M.P, Leadlay, P.F, Weissman, K.J. | Deposit date: | 2003-07-14 | Release date: | 2004-02-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of docking domains in modular polyketide synthases. Chem.Biol., 10, 2003
|
|
1PZQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pzq by Molmil](/molmil-images/mine/1pzq) | Structure of fused docking domains from the erythromycin polyketide synthase (DEBS), a model for the interaction between DEBS 2 and DEBS 3: The A domain | Descriptor: | Erythronolide synthase | Authors: | Broadhurst, R.W, Nietlispach, D, Wheatcroft, M.P, Leadlay, P.F, Weissman, K.J. | Deposit date: | 2003-07-14 | Release date: | 2004-02-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of docking domains in modular polyketide synthases. Chem.Biol., 10, 2003
|
|
2MF4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mf4 by Molmil](/molmil-images/mine/2mf4) | 1H, 13C, 15N chemical shift assignments of Streptomyces virginiae VirA acp5a | Descriptor: | Hybrid polyketide synthase-non ribosomal peptide synthetase | Authors: | Davison, J, Dorival, J, Rabeharindranto, M.H, Mazon, H, Chagot, B, Gruez, A, Weissman, K.J. | Deposit date: | 2013-10-05 | Release date: | 2014-06-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR assignements of ACP5a To be Published
|
|
2N5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n5d by Molmil](/molmil-images/mine/2n5d) | NMR structure of PKS domains | Descriptor: | fusion protein of two PKS domains | Authors: | Dorival, J, Annaval, T, Risser, F, Collin, S, Roblin, P, Jacob, C, Gruez, A, Chagot, B, Weissman, K.J. | Deposit date: | 2015-07-14 | Release date: | 2016-03-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase. J.Am.Chem.Soc., 138, 2016
|
|
6F7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f7l by Molmil](/molmil-images/mine/6f7l) | Crystal structure of LkcE R326Q mutant in complex with its substrate | Descriptor: | ACETATE ION, Amine oxidase LkcE, CALCIUM ION, ... | Authors: | Dorival, J, Risser, F, Jacob, C, Collin, S, Drager, G, Kirschning, A, Paris, C, Chagot, B, Gruez, A, Weissman, K.J. | Deposit date: | 2017-12-11 | Release date: | 2018-09-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis. Nat Commun, 9, 2018
|
|
6FJH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fjh by Molmil](/molmil-images/mine/6fjh) | Crystal structure of the seleniated LkcE from Streptomyces rochei | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LkcE, OXYGEN MOLECULE, ... | Authors: | Dorival, J, Risser, F, Jacob, C, Collin, S, Drager, G, Kirschning, A, Paris, C, Chagot, B, Gruez, A, Weissman, K.J. | Deposit date: | 2018-01-22 | Release date: | 2018-09-19 | Last modified: | 2018-10-10 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis. Nat Commun, 9, 2018
|
|
6F7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f7v by Molmil](/molmil-images/mine/6f7v) | Crystal structure of LkcE E64Q mutant in complex with LC-KA05 | Descriptor: | CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Dorival, J, Risser, F, Jacob, C, Collin, S, Drager, G, Kirschning, A, Paris, C, Chagot, B, Gruez, A, Weissman, K.J. | Deposit date: | 2017-12-12 | Release date: | 2018-09-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis. Nat Commun, 9, 2018
|
|
6F32
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f32 by Molmil](/molmil-images/mine/6f32) | Crystal structure of a dual function amine oxidase/cyclase in complex with substrate analogues | Descriptor: | (2~{R},3~{R})-2,3-bis(oxidanyl)-~{N},~{N}'-dipropyl-butanediamide, ACETATE ION, Amine oxidase LkcE, ... | Authors: | Dorival, J, Risser, F, Jacob, C, Collin, S, Drager, G, Kirschning, A, Paris, C, Chagot, B, Gruez, A, Weissman, K.J. | Deposit date: | 2017-11-27 | Release date: | 2018-09-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis. Nat Commun, 9, 2018
|
|