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PDB: 74 件
1VYB
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BU of 1vyb by Molmil
Endonuclease domain of human LINE1 ORF2p
分子名称: GLYCEROL, ORF2 CONTAINS A REVERSE TRANSCRIPTASE DOMAIN, SULFATE ION, ...
著者Weichenrieder, O, Repanas, K, Perrakis, A.
登録日2004-04-25
公開日2004-06-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon.
Structure, 12, 2004
1E8S
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BU of 1e8s by Molmil
Alu domain of the mammalian SRP (potential Alu retroposition intermediate)
分子名称: 7SL RNA, 88-MER, EUROPIUM (III) ION, ...
著者Weichenrieder, O, Wild, K, Strub, K, Cusack, S.
登録日2000-09-29
公開日2000-11-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle
Nature, 408, 2000
1E8O
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BU of 1e8o by Molmil
Core of the Alu domain of the mammalian SRP
分子名称: 7SL RNA, SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN, SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN, ...
著者Weichenrieder, O, Wild, K, Strub, K, Cusack, S.
登録日2000-09-28
公開日2000-11-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle
Nature, 408, 2000
5ABY
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BU of 5aby by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli
分子名称: 4E-BINDING PROTEIN MEXTLI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-3, GLYCEROL, ...
著者Peter, D, Weichenrieder, O.
登録日2015-08-09
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
4GMJ
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BU of 4gmj by Molmil
Structure of human NOT1 MIF4G domain co-crystallized with CAF1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ...
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
5ABX
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BU of 5abx by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli and cap analog
分子名称: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Peter, D, Weichenrieder, O.
登録日2015-08-09
公開日2015-09-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
4GML
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BU of 4gml by Molmil
Crystal structure of human NOT1 MIF4G domain
分子名称: CCR4-NOT transcription complex subunit 1
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
5LSW
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BU of 5lsw by Molmil
A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell differentiation protein RCD1 homolog, LD12033p, ...
著者Sgromo, A, Raisch, T, Bawankar, P, Bhandari, D, Chen, Y, Kuzuoglu-Ozturk, D, Weichenrieder, O, Izaurralde, E.
登録日2016-09-05
公開日2017-02-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
Nat Commun, 8, 2017
7AX1
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BU of 7ax1 by Molmil
Crystal structure of the human CCR4-CAF1 complex
分子名称: CCR4-NOT transcription complex subunit 6, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION
著者Chen, Y, Khazina, E, Weichenrieder, O.
登録日2020-11-09
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex.
Nucleic Acids Res., 49, 2021
4WBQ
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BU of 4wbq by Molmil
Crystal structure of the exonuclease domain of QIP (QDE-2 interacting protein) solved by native-SAD phasing.
分子名称: CALCIUM ION, QDE-2-interacting protein
著者Boland, A, Weinert, T, Weichenrieder, O, Wang, M.
登録日2014-09-03
公開日2014-12-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.693 Å)
主引用文献Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
2CKL
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BU of 2ckl by Molmil
Ring1b-Bmi1 E3 catalytic domain structure
分子名称: IODIDE ION, POLYCOMB GROUP RING FINGER PROTEIN 4, UBIQUITIN LIGASE PROTEIN RING2, ...
著者Buchwald, G, van der Stoop, P, Weichenrieder, O, Perrakis, A, van Lohuizen, M, Sixma, T.K.
登録日2006-04-20
公開日2006-05-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B.
Embo J., 25, 2006
6FIA
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BU of 6fia by Molmil
Structure of the human LINE-1 ORF1p coiled coil domain
分子名称: CHLORIDE ION, LINE-1 retrotransposable element ORF1 protein
著者Khazina, E, Weichenrieder, O.
登録日2018-01-17
公開日2018-03-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p.
Elife, 7, 2018
4UE9
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BU of 4ue9 by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein 4E-T
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEC
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BU of 4uec by Molmil
Complex of D. melanogaster eIF4E with eIF4G and cap analog
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, ...
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UED
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BU of 4ued by Molmil
Complex of human eIF4E with the 4E binding protein 4E-BP1
分子名称: EUKARYOTIC TRANSLATION FACTOR 4E-BINDING PROTEIN 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UE8
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BU of 4ue8 by Molmil
Complex of D. melanogaster eIF4E with the 4E binding protein Thor
分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 4E-BINDING PROTEIN THOR, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, ...
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEA
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BU of 4uea by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form I)
分子名称: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
6HOM
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BU of 6hom by Molmil
Drosophila NOT4 CBM peptide bound to human CAF40
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CCR4-NOT transcription complex subunit 4, isoform L, ...
著者Raisch, T, Izaurralde, E, Weichenrieder, O.
登録日2018-09-17
公開日2019-02-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Genes Dev., 33, 2019
6HON
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BU of 6hon by Molmil
Drosophila NOT4 CBM peptide bound to human CAF40
分子名称: CCR4-NOT transcription complex subunit 4, isoform L, CCR4-NOT transcription complex subunit 9, ...
著者Raisch, T, Izaurralde, E, Weichenrieder, O.
登録日2018-09-17
公開日2019-02-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Genes Dev., 33, 2019
6H3Z
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BU of 6h3z by Molmil
Crystal structure of a C-terminal MIF4G domain in NOT1
分子名称: CCR4-not transcription complex subunit 1, SODIUM ION
著者Raisch, T, Sandmeir, F, Weichenrieder, O, Valkov, E, Izaurralde, E.
登録日2018-07-19
公開日2018-11-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex.
J. Struct. Biol., 204, 2018
5FU6
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BU of 5fu6 by Molmil
NOT module of the human CCR4-NOT complex (Crystallization mutant)
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
著者Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
登録日2016-01-21
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
1D4R
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BU of 1d4r by Molmil
29-mer fragment of human srp rna helix 6
分子名称: 29-MER OF MODIFIED SRP RNA HELIX 6, MAGNESIUM ION
著者Wild, K, Weichenrieder, O, Leonard, G.A, Cusack, S.
登録日1999-10-05
公開日1999-12-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2 A structure of helix 6 of the human signal recognition particle RNA
Structure Fold.Des., 7, 1999
5FU7
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BU of 5fu7 by Molmil
drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ...
著者Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
登録日2016-01-21
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
5ONA
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BU of 5ona by Molmil
Drosophila Bag-of-marbles CBM peptide bound to human CAF40-CNOT1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 9, CHLORIDE ION, ...
著者Raisch, T, Sgromo, A, Backhaus, C, Izaurralde, E, Weichenrieder, O.
登録日2017-08-03
公開日2017-12-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
RNA, 24, 2018
5J3T
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BU of 5j3t by Molmil
Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex
分子名称: Edc1, FORMIC ACID, MAGNESIUM ION, ...
著者Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2016-03-31
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016

 

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