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PDB: 74 results

5T46
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Crystal structure of the human eIF4E-eIF4G complex
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5J3Q
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Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex
Descriptor: Edc1, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5ABV
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BU of 5abv by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GH11071P
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5AOX
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Human Alu RNA retrotransposition complex in the ribosome-stalling conformation
Descriptor: ACETATE ION, ALU JO CONSENSUS RNA, DI(HYDROXYETHYL)ETHER, ...
Authors:Ahl, V, Weichenrieder, O.
Deposit date:2015-09-12
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Retrotransposition and Crystal Structure of an Alu Rnp in the Ribosome-Stalling Conformation.
Mol.Cell, 60, 2015
5J3Y
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BU of 5j3y by Molmil
Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex
Descriptor: mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.288 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5ABU
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Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog
Descriptor: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, CHLORIDE ION, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ONB
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BU of 5onb by Molmil
Drosophila Bag-of-marbles CBM peptide bound to human CAF40
Descriptor: CCR4-NOT transcription complex subunit 9, GLYCEROL, Protein bag-of-marbles
Authors:Raisch, T, Sgromo, A, Backhaus, C, Izaurralde, E, Weichenrieder, O.
Deposit date:2017-08-03
Release date:2017-12-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
RNA, 24, 2018
5T47
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Crystal structure of the D. melanogaster eIF4E-eIF4G complex
Descriptor: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T48
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Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
4UEB
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Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form II)
Descriptor: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4C0G
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BU of 4c0g by Molmil
Structure of the NOT-box domain of human CNOT3
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
Authors:Boland, A, Chen, Y, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O.
Deposit date:2013-08-01
Release date:2013-10-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
3ZHE
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BU of 3zhe by Molmil
Structure of the C. elegans SMG5-SMG7 complex
Descriptor: NONSENSE-MEDIATED MRNA DECAY PROTEIN, PROTEIN SMG-7
Authors:Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2012-12-21
Release date:2013-02-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:An Unusual Arrangement of Two 14-3-3-Like Domains in the Smg5-Smg7 Heterodimer is Required for Efficient Nonsense-Mediated Mrna Decay.
Genes Dev., 27, 2013
4C0E
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BU of 4c0e by Molmil
Structure of the NOT1 superfamily homology domain from Chaetomium thermophilum
Descriptor: NOT1
Authors:Chen, Y, Boland, A, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O.
Deposit date:2013-08-01
Release date:2013-10-09
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
2YLC
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BU of 2ylc by Molmil
Structure of Salmonella typhimurium Hfq in complex with U6 RNA
Descriptor: PROTEIN HFQ, THIOCYANATE ION, URIDINE-5'-MONOPHOSPHATE
Authors:Sauer, E, Weichenrieder, O.
Deposit date:2011-06-01
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Basis for RNA 3' End Recognition by Hfq
Proc.Natl.Acad.Sci.USA, 108, 2011
2YLB
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BU of 2ylb by Molmil
Structure of Salmonella typhimurium Hfq at 1.15 A
Descriptor: PROTEIN HFQ
Authors:Sauer, E, Weichenrieder, O.
Deposit date:2011-06-01
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural Basis for RNA 3' End Recognition by Hfq
Proc.Natl.Acad.Sci.USA, 108, 2011
2YKO
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BU of 2yko by Molmil
Structure of the human LINE-1 ORF1p trimer
Descriptor: CHLORIDE ION, LINE-1 ORF1P
Authors:Khazina, E, Weichenrieder, O.
Deposit date:2011-05-28
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Trimeric Structure and Flexibility of the L1Orf1P Protein in Human L1 Retrotransposition
Nat.Struct.Mol.Biol., 18, 2011
2YKP
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BU of 2ykp by Molmil
Structure of the human LINE-1 ORF1p trimer
Descriptor: CHLORIDE ION, LINE-1 ORF1P
Authors:Khazina, E, Weichenrieder, O.
Deposit date:2011-05-28
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Trimeric Structure and Flexibility of the L1Orf1P Protein in Human L1 Retrotransposition
Nat.Struct.Mol.Biol., 18, 2011
2YKQ
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BU of 2ykq by Molmil
Structure of the human LINE-1 ORF1p trimer
Descriptor: CHLORIDE ION, LINE-1 ORF1P
Authors:Khazina, E, Weichenrieder, O.
Deposit date:2011-05-28
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Trimeric Structure and Flexibility of the L1Orf1P Protein in Human L1 Retrotransposition
Nat.Struct.Mol.Biol., 18, 2011
2WAX
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BU of 2wax by Molmil
Structure of the human DDX6 C-terminal domain in complex with an EDC3- FDF peptide
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ATP-DEPENDENT RNA HELICASE DDX6, ENHANCER OF MRNA-DECAPPING PROTEIN 3, ...
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2009-02-18
Release date:2009-03-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.
Mol.Cell, 33, 2009
2YHB
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BU of 2yhb by Molmil
Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains
Descriptor: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION
Authors:Boland, A, Weichenrieder, O.
Deposit date:2011-04-27
Release date:2011-06-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein
Proc.Natl.Acad.Sci.USA, 108, 2011
2WX4
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BU of 2wx4 by Molmil
Asymmetric trimer of the Drosophila melanogaster DCP1 C-terminal domain
Descriptor: DECAPPING PROTEIN 1, SULFATE ION
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2009-11-01
Release date:2009-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dcp1 Forms Asymmetric Trimers to Assemble Into Active Mrna Decapping Complexes in Metazoa.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WX3
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BU of 2wx3 by Molmil
Asymmetric trimer of the human DCP1a C-terminal domain
Descriptor: MRNA-DECAPPING ENZYME 1A
Authors:Tritschler, F, Motz, C, Weichenrieder, O.
Deposit date:2009-11-01
Release date:2009-12-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Dcp1 Forms Asymmetric Trimers to Assemble Into Active Mrna Decapping Complexes in Metazoa.
Proc.Natl.Acad.Sci.USA, 106, 2009
2XES
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BU of 2xes by Molmil
Human PatL1 C-terminal domain (loop variant)
Descriptor: POTASSIUM ION, PROTEIN PAT1 HOMOLOG 1, THIOCYANATE ION
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2010-05-17
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010
2XEQ
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BU of 2xeq by Molmil
Human PatL1 C-terminal domain
Descriptor: PAT1 HOMOLOG 1,
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2010-05-17
Release date:2010-06-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010
2VC8
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BU of 2vc8 by Molmil
Crystal structure of the LSm domain of human EDC3 (enhancer of decapping 3)
Descriptor: ENHANCER OF MRNA-DECAPPING PROTEIN 3
Authors:Tritschler, F, Hartmann, M.D, Weichenrieder, O.
Deposit date:2007-09-19
Release date:2007-10-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:A Divergent Sm Fold in Edc3 Proteins Mediates Dcp1 Binding and P-Body Targeting.
Mol.Cell.Biol., 27, 2007

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