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PDB: 74 results
4UEB
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BU of 4ueb by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form II)
Descriptor: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
5ABY
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BU of 5aby by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli
Descriptor: 4E-BINDING PROTEIN MEXTLI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-3, GLYCEROL, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
4UE9
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BU of 4ue9 by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein 4E-T
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEC
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BU of 4uec by Molmil
Complex of D. melanogaster eIF4E with eIF4G and cap analog
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UED
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BU of 4ued by Molmil
Complex of human eIF4E with the 4E binding protein 4E-BP1
Descriptor: EUKARYOTIC TRANSLATION FACTOR 4E-BINDING PROTEIN 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UE8
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BU of 4ue8 by Molmil
Complex of D. melanogaster eIF4E with the 4E binding protein Thor
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 4E-BINDING PROTEIN THOR, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
5AOX
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BU of 5aox by Molmil
Human Alu RNA retrotransposition complex in the ribosome-stalling conformation
Descriptor: ACETATE ION, ALU JO CONSENSUS RNA, DI(HYDROXYETHYL)ETHER, ...
Authors:Ahl, V, Weichenrieder, O.
Deposit date:2015-09-12
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Retrotransposition and Crystal Structure of an Alu Rnp in the Ribosome-Stalling Conformation.
Mol.Cell, 60, 2015
5ABV
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BU of 5abv by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GH11071P
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ABX
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BU of 5abx by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli and cap analog
Descriptor: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ABU
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BU of 5abu by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog
Descriptor: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, CHLORIDE ION, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
4UEA
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BU of 4uea by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form I)
Descriptor: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
2WAX
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BU of 2wax by Molmil
Structure of the human DDX6 C-terminal domain in complex with an EDC3- FDF peptide
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ATP-DEPENDENT RNA HELICASE DDX6, ENHANCER OF MRNA-DECAPPING PROTEIN 3, ...
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2009-02-18
Release date:2009-03-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.
Mol.Cell, 33, 2009
2VC8
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BU of 2vc8 by Molmil
Crystal structure of the LSm domain of human EDC3 (enhancer of decapping 3)
Descriptor: ENHANCER OF MRNA-DECAPPING PROTEIN 3
Authors:Tritschler, F, Hartmann, M.D, Weichenrieder, O.
Deposit date:2007-09-19
Release date:2007-10-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:A Divergent Sm Fold in Edc3 Proteins Mediates Dcp1 Binding and P-Body Targeting.
Mol.Cell.Biol., 27, 2007
2V0S
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BU of 2v0s by Molmil
crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease
Descriptor: GLYCEROL, LR1, MANGANESE (II) ION, ...
Authors:Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
Deposit date:2007-05-17
Release date:2007-07-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease.
Nucleic Acids Res., 35, 2007
2WAY
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BU of 2way by Molmil
Structure of the human DDX6 C-terminal domain in complex with an EDC3- FDF peptide
Descriptor: ATP-DEPENDENT RNA HELICASE DDX6, ENHANCER OF MRNA-DECAPPING PROTEIN 3, GLYCEROL
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2009-02-18
Release date:2009-03-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.
Mol.Cell, 33, 2009
2W7A
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BU of 2w7a by Molmil
Structure of the human LINE-1 ORF1p central domain
Descriptor: LINE-1 ORF1P, MALONATE ION
Authors:Khazina, E, Weichenrieder, O.
Deposit date:2008-12-22
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Non-Ltr Retrotransposons Encode Noncanonical Rrm Domains in Their First Open Reading Frame.
Proc.Natl.Acad.Sci.USA, 106, 2009
2V0R
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BU of 2v0r by Molmil
crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease
Descriptor: LTX, SULFATE ION
Authors:Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
Deposit date:2007-05-17
Release date:2007-07-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease
Nucleic Acids Res., 35, 2007
2WX3
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BU of 2wx3 by Molmil
Asymmetric trimer of the human DCP1a C-terminal domain
Descriptor: MRNA-DECAPPING ENZYME 1A
Authors:Tritschler, F, Motz, C, Weichenrieder, O.
Deposit date:2009-11-01
Release date:2009-12-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Dcp1 Forms Asymmetric Trimers to Assemble Into Active Mrna Decapping Complexes in Metazoa.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WX4
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BU of 2wx4 by Molmil
Asymmetric trimer of the Drosophila melanogaster DCP1 C-terminal domain
Descriptor: DECAPPING PROTEIN 1, SULFATE ION
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2009-11-01
Release date:2009-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dcp1 Forms Asymmetric Trimers to Assemble Into Active Mrna Decapping Complexes in Metazoa.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WBR
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BU of 2wbr by Molmil
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
Descriptor: GW182
Authors:Eulalio, A, Tritschler, F, Buettner, R, Weichenrieder, O, Izaurralde, E, Truffault, V.
Deposit date:2009-03-03
Release date:2009-03-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Rrm Domain in Gw182 Proteins Contributes to Mirna-Mediated Gene Silencing.
Nucleic Acids Res., 37, 2009
2YLC
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BU of 2ylc by Molmil
Structure of Salmonella typhimurium Hfq in complex with U6 RNA
Descriptor: PROTEIN HFQ, THIOCYANATE ION, URIDINE-5'-MONOPHOSPHATE
Authors:Sauer, E, Weichenrieder, O.
Deposit date:2011-06-01
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Basis for RNA 3' End Recognition by Hfq
Proc.Natl.Acad.Sci.USA, 108, 2011
2YLB
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BU of 2ylb by Molmil
Structure of Salmonella typhimurium Hfq at 1.15 A
Descriptor: PROTEIN HFQ
Authors:Sauer, E, Weichenrieder, O.
Deposit date:2011-06-01
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural Basis for RNA 3' End Recognition by Hfq
Proc.Natl.Acad.Sci.USA, 108, 2011
2XEQ
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BU of 2xeq by Molmil
Human PatL1 C-terminal domain
Descriptor: PAT1 HOMOLOG 1,
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2010-05-17
Release date:2010-06-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010
2YKO
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BU of 2yko by Molmil
Structure of the human LINE-1 ORF1p trimer
Descriptor: CHLORIDE ION, LINE-1 ORF1P
Authors:Khazina, E, Weichenrieder, O.
Deposit date:2011-05-28
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Trimeric Structure and Flexibility of the L1Orf1P Protein in Human L1 Retrotransposition
Nat.Struct.Mol.Biol., 18, 2011
2XER
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BU of 2xer by Molmil
Human PatL1 C-terminal domain (loop variant with sulfates)
Descriptor: PAT1 HOMOLOG 1, SULFATE ION
Authors:Tritschler, F, Weichenrieder, O.
Deposit date:2010-05-17
Release date:2010-06-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010

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