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PDB: 86 results

1JKM
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BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE
Descriptor: BREFELDIN A ESTERASE
Authors:Wei, Y, Contreras, A.J, Sheffield, P, Osterlund, T, Derewenda, U, Matern, U.O, Derewenda, Z.S.
Deposit date:1998-02-04
Release date:1999-02-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase.
Nat.Struct.Biol., 6, 1999
8WFK
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human glycine transporter 1 in complex with SSR504734 in outward facing conformation
Descriptor: CHLORIDE ION, SODIUM ION, SSR504734, ...
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFI
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BU of 8wfi by Molmil
human glycine transporter 1 in complex with glycine in occluded conformation
Descriptor: CHLORIDE ION, GLYCINE, Isoform GlyT-1B of Sodium- and chloride-dependent glycine transporter 1, ...
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFL
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human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
Descriptor: PF-3463275, Sodium- and chloride-dependent glycine transporter 1
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFJ
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human glycine transporter 1 in complex with ALX-5407 in inward facing conformation
Descriptor: ALX5407, Sodium- and chloride-dependent glycine transporter 1
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
1ESC
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BU of 1esc by Molmil
THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
Descriptor: ESTERASE
Authors:Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S.
Deposit date:1994-10-07
Release date:1995-10-15
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
1F1J
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BU of 1f1j by Molmil
CRYSTAL STRUCTURE OF CASPASE-7 IN COMPLEX WITH ACETYL-ASP-GLU-VAL-ASP-CHO
Descriptor: ACE-ASP-GLU-VAL-ASP-CHO, CASPASE-7 PROTEASE, SULFATE ION
Authors:Wei, Y, Charifson, P.S.
Deposit date:2000-05-19
Release date:2001-05-23
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity.
Chem.Biol., 7, 2000
1ESD
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BU of 1esd by Molmil
THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
Descriptor: ESTERASE, METHYLPHOSPHONIC ACID ESTER GROUP
Authors:Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S.
Deposit date:1994-10-07
Release date:1995-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
1ESE
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BU of 1ese by Molmil
THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES
Descriptor: DIETHYL PHOSPHONATE, ESTERASE
Authors:Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S.
Deposit date:1994-10-07
Release date:1995-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
5I8J
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BU of 5i8j by Molmil
Crystal structure of Dmd from phage RB69
Descriptor: Dmd discriminator of mRNA degradation
Authors:Wei, Y, Zhang, H, Gao, Z.Q, Dong, Y.H.
Deposit date:2016-02-19
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural characterizations of phage antitoxin Dmd and its interactions with bacterial toxin RnlA
Biochem. Biophys. Res. Commun., 472, 2016
1FTN
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BU of 1ftn by Molmil
CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12)
Authors:Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S.
Deposit date:1997-03-13
Release date:1998-03-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
6E24
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BU of 6e24 by Molmil
Ternary structure of c-Myc-TBP-TAF1
Descriptor: Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein
Authors:Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2018-07-10
Release date:2019-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
6E16
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BU of 6e16 by Molmil
Ternary structure of c-Myc-TBP-TAF1
Descriptor: Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein
Authors:Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2018-07-09
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
6P6B
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BU of 6p6b by Molmil
CS-Rosetta Model of PEA-15 Death Effector Domain
Descriptor: Astrocytic phosphoprotein PEA-15
Authors:Wei, Y, Crespo Flores, S, Cabezas, A, Hassan, S.
Deposit date:2019-06-03
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PEA-15 C-Terminal Tail Allosterically Modulates Death-Effector Domain Conformation and Facilitates Protein-Protein Interactions.
Int J Mol Sci, 20, 2019
6P6C
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BU of 6p6c by Molmil
CS-Rosetta Model of PEA-15 Death Effector Domain in the Complex with ERK2
Descriptor: Astrocytic phosphoprotein PEA-15
Authors:Wei, Y, Crespo Flores, S, Cabezas, A, Hassan, S.
Deposit date:2019-06-03
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PEA-15 C-Terminal Tail Allosterically Modulates Death-Effector Domain Conformation and Facilitates Protein-Protein Interactions.
Int J Mol Sci, 20, 2019
4I8O
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BU of 4i8o by Molmil
Crystal structure of the toxin RnlA from Escherichia coli
Descriptor: TOXIN RNLA
Authors:Wei, Y, Gao, Z.Q, Zhang, H, Dong, Y.H.
Deposit date:2012-12-04
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Structure-function studies of Escherichia coli RnlA reveal a novel toxin structure involved in bacteriophage resistance.
Mol.Microbiol., 90, 2013
1JFR
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BU of 1jfr by Molmil
CRYSTAL STRUCTURE OF THE STREPTOMYCES EXFOLIATUS LIPASE AT 1.9A RESOLUTION: A MODEL FOR A FAMILY OF PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES
Descriptor: LIPASE
Authors:Wei, Y, Derewenda, Z.S.
Deposit date:1997-07-11
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution.
Structure, 6, 1998
6E8N
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BU of 6e8n by Molmil
Crystal structure of glycosylated human EPDR1
Descriptor: Mammalian ependymin-related protein 1, NONAETHYLENE GLYCOL
Authors:Wei, Y, Prive, G.G.
Deposit date:2018-07-30
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.
Commun Biol, 2, 2019
6E7O
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BU of 6e7o by Molmil
Crystal structure of deglycosylated human EPDR1
Descriptor: Mammalian ependymin-related protein 1
Authors:Wei, Y, Prive, G.G.
Deposit date:2018-07-27
Release date:2019-01-23
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters.
Commun Biol, 2, 2019
4EFE
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BU of 4efe by Molmil
crystal structure of DNA ligase
Descriptor: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, SULFATE ION, ...
Authors:Wei, Y, Wang, T, Charifson, P, Xu, W.
Deposit date:2012-03-29
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:crystal structure of DNA ligase
To be Published
4EFB
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BU of 4efb by Molmil
Crystal structure of DNA ligase
Descriptor: 4-amino-2-(cyclopentyloxy)-6-{[(1R,2S)-2-hydroxycyclopentyl]oxy}pyrimidine-5-carboxamide, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, ...
Authors:Wei, Y, Wang, T, Charifson, P, Xu, W.
Deposit date:2012-03-29
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of DNA ligase
To be Published
1P68
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BU of 1p68 by Molmil
Solution structure of S-824, a de novo designed four helix bundle
Descriptor: De novo designed protein S-824
Authors:Wei, Y, Kim, S, Fela, D, Baum, J, Hecht, M.H.
Deposit date:2003-04-29
Release date:2003-11-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a de novo protein from a designed combinatorial library.
Proc.Natl.Acad.Sci.Usa, 100, 2003
1S16
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BU of 1s16 by Molmil
Crystal Structure of E. coli Topoisomerase IV ParE 43kDa subunit complexed with ADPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ...
Authors:Wei, Y, Gross, C.H.
Deposit date:2004-01-05
Release date:2004-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyrase.
Antimicrob.Agents Chemother., 48, 2004
1S14
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BU of 1s14 by Molmil
Crystal structure of Escherichia coli Topoisomerase IV ParE 24kDa subunit
Descriptor: NOVOBIOCIN, Topoisomerase IV subunit B
Authors:Wei, Y, Gross, C.H.
Deposit date:2004-01-05
Release date:2004-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyrase.
Antimicrob.Agents Chemother., 48, 2004
1B62
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BU of 1b62 by Molmil
MUTL COMPLEXED WITH ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (MUTL)
Authors:Wei, Y.
Deposit date:1999-01-11
Release date:1999-04-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair.
Cell(Cambridge,Mass.), 97, 1999

 

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