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PDB: 120 件

7O1H
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Hybrid-2R quadruplex-duplex with (-p-p-l) topology and 3 syn residues
分子名称: DNA (31-MER)
著者Mohr, S, Vianney, Y.M, Weisz, K.
登録日2021-03-29
公開日2021-05-19
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Expanding the Topological Landscape by a G-Column Flip of a Parallel G-Quadruplex.
Chemistry, 27, 2021
6ZL9
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Structure of a parallel c-Myc modified with 5' duplex stem-loop overhang
分子名称: DNA (35-MER)
著者Vianney, Y.M, Weisz, K.
登録日2020-06-30
公開日2020-10-07
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
8A8U
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Mycobacterium tuberculosis ClpC1 hexamer structure
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
著者Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
登録日2022-06-24
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8A8V
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Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
著者Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
登録日2022-06-24
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8A8W
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Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
著者Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
登録日2022-06-24
公開日2022-10-26
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
6ZTE
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Structure of a parallel c-myc modified with 5' duplex stem-loop and 3' diagonal snap-back loop
分子名称: DNA (36-MER)
著者Vianney, Y.M, Weisz, K.
登録日2020-07-20
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
1E4Q
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Solution structure of the human defensin hBD-2
分子名称: BETA-DEFENSIN 2
著者Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H.
登録日2000-07-12
公開日2001-07-12
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure Determination of Human and Murine Beta-Defensins Reveals Structural Conservation in the Absence of Significant Sequence Similarity
Protein Sci., 10, 2001
1E4T
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Solution structure of the mouse defensin mBD-7
分子名称: Beta-defensin 7
著者Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H.
登録日2000-07-12
公開日2001-07-12
最終更新日2018-06-20
実験手法SOLUTION NMR
主引用文献Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
Protein Sci., 10, 2001
1E4R
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Solution structure of the mouse defensin mBD-8
分子名称: Beta-defensin 8
著者Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H.
登録日2000-07-12
公開日2001-07-12
最終更新日2018-06-20
実験手法SOLUTION NMR
主引用文献Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
Protein Sci., 10, 2001
7PNE
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Parallel Q-D hybrid with 3' duplex stem-loop as a lateral snapback loop
分子名称: TTAMycdup-3sbl
著者Vianney, Y.M, Weisz, K.
登録日2021-09-06
公開日2021-12-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
7PNG
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Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid
分子名称: DNA (37-MER), ~{N}-(5~{H}-indolo[3,2-b]quinolin-11-yl)-~{N}',~{N}'-dimethyl-propane-1,3-diamine
著者Vianney, Y.M, Weisz, K.
登録日2021-09-06
公開日2021-12-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
8QKX
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Solution structure of a bimolecular quadruplex-duplex hybrid containing a V-shaped loop
分子名称: DNA (5'-D(*CP*TP*CP*CP*AP*GP*CP*TP*GP*GP*GP*TP*GP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*GP*CP*TP*GP*GP*AP*GP*TP*T)-3')
著者Vianney, Y.M, Weisz, K.
登録日2023-09-18
公開日2024-02-07
実験手法SOLUTION NMR
主引用文献Structural Aspects of Split G-Quadruplexes in Quadruplex-Duplex Hybrid Systems
Chemistryselect, 2024
8R6D
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BU of 8r6d by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology
分子名称: DNA (31-MER)
著者Vianney, Y.M, Weisz, K.
登録日2023-11-22
公開日2024-03-06
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
8R6G
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A quadruplex-duplex hybrid with a three-layered chair G-quadruplex topology
分子名称: DNA (33-MER)
著者Vianney, Y.M, Weisz, K.
登録日2023-11-22
公開日2024-03-13
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
8R6H
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BU of 8r6h by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology complexed with Phen-DC3
分子名称: DNA (34-MER), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
著者Vianney, Y.M, Weisz, K.
登録日2023-11-22
公開日2024-03-06
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
8R4E
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BU of 8r4e by Molmil
Hybrid-1R G-quadruplex with a +(lpp) loop progression
分子名称: DNA (27-MER)
著者Jana, J, Vianney, Y.M, Weisz, K.
登録日2023-11-13
公開日2023-12-27
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
Chem.Commun.(Camb.), 60, 2024
8R4W
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(3+1) hybrid-2 G-quadruplex with a -(llp) loop progression
分子名称: DNA (25-MER)
著者Jana, J, Vianney, Y.M, Weisz, K.
登録日2023-11-14
公開日2023-12-27
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
Chem.Commun.(Camb.), 60, 2024
8TCE
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BU of 8tce by Molmil
Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3353871
分子名称: (2S)-3-phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic acid, Apolipoprotein(a)
著者Hendle, J, Weichert, K, Sauder, J.M.
登録日2023-06-30
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024
8S1W
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BU of 8s1w by Molmil
Structure of a quadruplex-duplex hybrid with a (-pd+l) loop progression
分子名称: DNA (33-MER)
著者Vianney, Y.M, Jana, J, Weisz, K.
登録日2024-02-16
公開日2024-03-27
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
8RW2
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Structure of a chair-type antiparallel quadruplex-duplex hybrid at pH 6
分子名称: DNA (33-MER)
著者Vianney, Y.M, Weisz, K.
登録日2024-02-02
公開日2024-03-27
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
8PSI
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BU of 8psi by Molmil
G-quadruplex with a 1-nt V-shaped loop from a G-rich sequence with five G-runs
分子名称: DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Schroeder, N, Jana, J, Weisz, K.
登録日2023-07-13
公開日2023-09-27
最終更新日2023-10-18
実験手法SOLUTION NMR
主引用文献Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8PSC
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Three-layered basket-type G-quadruplex from a G-rich sequence with five G-runs
分子名称: DNA (5'-D(*AP*GP*(BG)P*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Schroeder, N, Jana, J, Weisz, K.
登録日2023-07-13
公開日2023-09-27
最終更新日2023-10-18
実験手法SOLUTION NMR
主引用文献Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8PSB
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BU of 8psb by Molmil
Three-layered parallel G-quadruplex with snapback loop from a G-rich sequence with five G-runs
分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*AP*CP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Schroeder, N, Jana, J, Chojetzki, G, Weisz, K.
登録日2023-07-13
公開日2023-09-27
最終更新日2023-10-25
実験手法SOLUTION NMR
主引用文献Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8V9B
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Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732
分子名称: (2S,2'S)-3,3'-[carbonylbis(azanediyl-3,1-phenylene)]bis{2-[(3R)-pyrrolidin-1-ium-3-yl]propanoate}, Apolipoprotein(a), MAGNESIUM ION, ...
著者Hendle, J, Weichert, K, Sauder, J.M.
登録日2023-12-07
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024
8V8Z
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Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3473329
分子名称: Apolipoprotein(a), muvalaplin
著者Hendle, J, Weichert, K, Sauder, J.M.
登録日2023-12-06
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024

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