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PDB: 49 件

4ILG
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Crystal structure of Aar2p in complex with the Prp8p RNaseH and Jab1/MPN domains
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weber, G, Heroven, A.C, Santos, K.F, Wahl, M.C.
登録日2012-12-31
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for dual roles of Aar2p in U5 snRNP assembly.
Genes Dev., 27, 2013
4ILJ
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BU of 4ilj by Molmil
Crystal structure of an Prp8p RNaseH W1911A mutant protein
分子名称: Pre-mRNA-splicing factor 8
著者Weber, G, Heroven, C, Santos, K.F, Wahl, M.C.
登録日2012-12-31
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.0001 Å)
主引用文献Structural basis for dual roles of Aar2p in U5 snRNP assembly.
Genes Dev., 27, 2013
4ILI
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BU of 4ili by Molmil
Crystal structure of an Aar2p S253E phosphomimetic mutant protein
分子名称: A1 cistron-splicing factor AAR2
著者Weber, G, Heroven, C, Santos, K.F, Wahl, M.C.
登録日2012-12-31
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2046 Å)
主引用文献Structural basis for dual roles of Aar2p in U5 snRNP assembly.
Genes Dev., 27, 2013
4ILH
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BU of 4ilh by Molmil
Crystal structure of an Aar2p C-terminal deletion mutant in conplex with Prp8p RNaseH
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weber, G, Heroven, A.C, Santos, K.F, Wahl, M.C.
登録日2012-12-31
公開日2013-03-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for the Aar2p-mediated regulation of Prp8p interactions with Brr2p and U4/U6 di-snRNA
To be Published
7O4F
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BU of 7o4f by Molmil
The DYW domain of A. thaliana OTP86 in its active state
分子名称: Pentatricopeptide repeat-containing protein At3g63370, chloroplastic, ZINC ION
著者Weber, G, Palm, G.J, Takenaka, M, Barthel, T, Feiler, C, Weiss, M.S.
登録日2021-04-06
公開日2021-06-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis.
Nat Catal, 4, 2021
7O4E
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The DYW domain of A. thaliana OTP86 in its inactive state
分子名称: Pentatricopeptide repeat-containing protein At3g63370, chloroplastic, ZINC ION
著者Weber, G, Palm, G.J, Takenaka, M, Barthel, T, Feiler, C, Weiss, M.S.
登録日2021-04-06
公開日2021-06-30
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis.
Nat Catal, 4, 2021
6F4G
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'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex
分子名称: CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ...
著者Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C.
登録日2017-11-29
公開日2018-06-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4J
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Crystal structure of Drosophila melanogaster SNF/U2A' complex
分子名称: POLYETHYLENE GLYCOL (N=34), Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ...
著者Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C.
登録日2017-11-29
公開日2018-06-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4H
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Crystal structure of the Drosophila melanogaster SNF/U1-SL2 complex
分子名称: CITRATE ANION, U1 small nuclear ribonucleoprotein A, U1-SL2
著者Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C.
登録日2017-11-29
公開日2018-06-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4I
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Crystal structure of Drosophila melanogaster SNF
分子名称: U1 small nuclear ribonucleoprotein A
著者Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C.
登録日2017-11-29
公開日2018-06-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
3PGW
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BU of 3pgw by Molmil
Crystal structure of human U1 snRNP
分子名称: DNA 5'-D(*AP*GP*GP*TP*AP*AP*GP*TP*A)-3', Sm B, Sm G, ...
著者Weber, G, Trowitzsch, S, Kastner, B, Luehrmann, R, Wahl, M.C.
登録日2010-11-02
公開日2010-12-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Functional organization of the Sm core in the crystal structure of human U1 snRNP.
Embo J., 29, 2010
3SBT
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BU of 3sbt by Molmil
Crystal structure of a Aar2-Prp8 complex
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, S-1,2-PROPANEDIOL, ...
著者Weber, G, Santos, K.F, Holton, N, Wahl, M.C.
登録日2011-06-06
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Mechanism for Aar2p function as a U5 snRNP assembly factor.
Genes Dev., 25, 2011
3SBS
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BU of 3sbs by Molmil
Crystal structure of Aar2 protein
分子名称: A1 cistron-splicing factor AAR2
著者Weber, G, Santos, K.F, Holton, N, Wahl, M.C.
登録日2011-06-06
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism for Aar2p function as a U5 snRNP assembly factor.
Genes Dev., 25, 2011
3SBG
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BU of 3sbg by Molmil
Crystal structure of a Prp8 C-terminal fragment
分子名称: Pre-mRNA-splicing factor 8
著者Weber, G, Santos, K, Holton, N, Wahl, M.C.
登録日2011-06-04
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Mechanism for Aar2p function as a U5 snRNP assembly factor.
Genes Dev., 25, 2011
2IOV
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BU of 2iov by Molmil
Bright-state structure of the reversibly switchable fluorescent protein Dronpa
分子名称: Fluorescent protein Dronpa
著者Stiel, A.C, Trowitzsch, S, Weber, G, Andresen, M, Eggeling, C, Hell, S.W, Jakobs, S, Wahl, M.C.
登録日2006-10-11
公開日2006-12-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants
Biochem.J., 402, 2007
3ELS
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BU of 3els by Molmil
Crystal Structure of Yeast Pml1p, Residues 51-204
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Trowitzsch, S, Weber, G, Luehrmann, R, Wahl, M.C.
登録日2008-09-23
公開日2009-02-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
J.Mol.Biol., 385, 2009
3ELV
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BU of 3elv by Molmil
Crystal Structure of Full-Length Yeast Pml1p
分子名称: Pre-mRNA leakage protein 1, SULFATE ION
著者Trowitzsch, S, Weber, G, L hrmann, R, Wahl, M.C.
登録日2008-09-23
公開日2009-02-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
J.Mol.Biol., 385, 2009
7OS2
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BU of 7os2 by Molmil
Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78
分子名称: Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Bergfort, A, Hilal, T, Weber, G, Wahl, M.C.
登録日2021-06-07
公開日2022-02-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
7OS1
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BU of 7os1 by Molmil
Cryo-EM structure of Brr2 in complex with Fbp21
分子名称: U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4
著者Bergfort, A, Hilal, T, Weber, G, Wahl, M.C.
登録日2021-06-07
公開日2022-02-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
7PJH
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BU of 7pjh by Molmil
Crystal structure of the human spliceosomal maturation factor AAR2 bound to the RNAse H domain of PRPF8
分子名称: Pre-mRNA-processing-splicing factor 8, Protein AAR2 homolog
著者Preussner, M, Santos, K, Heroven, A.C, Alles, J, Heyd, F, Wahl, M.C, Weber, G.
登録日2021-08-24
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8.
Acta Crystallogr D Struct Biol, 78, 2022
4RZ9
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BU of 4rz9 by Molmil
Pre-mRNA-splicing factor 38A AS 1-179
分子名称: Pre-mRNA-splicing factor 38A
著者Schuetze, T, Weber, G, Wahl, M.C.
登録日2014-12-19
公開日2015-12-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome
To be Published
5LM7
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BU of 5lm7 by Molmil
Crystal structure of the lambda N-Nus factor complex
分子名称: 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ...
著者Said, N, Santos, K, Weber, G, Wahl, M.C.
登録日2016-07-29
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
3LSA
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BU of 3lsa by Molmil
Padron0.9-OFF (non-fluorescent state)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ...
著者Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S.
登録日2010-02-12
公開日2010-03-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron.
J.Biol.Chem., 285, 2010
3LS3
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Padron0.9-ON (fluorescent state)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ...
著者Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S.
登録日2010-02-12
公開日2010-03-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron.
J.Biol.Chem., 285, 2010
6QG9
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Crystal structure of Ideonella sakaiensis MHETase
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Palm, G.J, Reisky, L, Boettcher, D, Mueller, H, Michels, E.A.P, Walczak, C, Berndt, L, Weiss, M.S, Bornscheuer, U.T, Weber, G.
登録日2019-01-10
公開日2019-04-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate.
Nat Commun, 10, 2019

 

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