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PDB: 659 件
2ON9
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Structure of an amyloid forming peptide VQIVYK from the repeat region of Tau
分子名称: VQIVYK peptide corresponding to residues 306-311 in the tau protein
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-23
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
7LUZ
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BU of 7luz by Molmil
GQTVTK segment from the Nucleoprotein of SARS-CoV-2, residues 243-248
分子名称: Nucleoprotein GQTVTK
著者Balbirnie, M, Sawaya, M.R, Eisenberg, D.S, Cascio, D.
登録日2021-02-23
公開日2021-03-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.101 Å)
主引用文献Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Biorxiv, 2021
5K7O
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BU of 5k7o by Molmil
MicroED structure of lysozyme at 1.8 A resolution
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
登録日2016-05-26
公開日2017-04-05
最終更新日2018-08-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.8 Å)
主引用文献Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
2OLX
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BU of 2olx by Molmil
Structure of NNQQ Peptide from Yeast Prion SUP35
分子名称: NNQQ peptide derived from Yeast Prion Sup35
著者Nelson, R, Sawaya, M.R, Eisenberg, D.
登録日2007-01-19
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2ONA
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BU of 2ona by Molmil
MVGGVV peptide derived from Alzheimer's A-beta, residues 35-40
分子名称: MVGGVV peptide derived from Alzheimer's A-beta, residues 35-40
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-23
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2OL9
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BU of 2ol9 by Molmil
Peptide corresponding to residues 170-175 of human prion
分子名称: peptide from human prion
著者Apostol, M.A, Sawaya, M.R, Eisenberg, D.
登録日2007-01-18
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2OMP
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BU of 2omp by Molmil
LYQLEN peptide derived from human insulin chain A, residues 13-18
分子名称: LYQLEN peptide derived from human insulin chain A, residues 13-18
著者Ivanova, M.I, Sawaya, M.R, Eisenberg, D.
登録日2007-01-22
公開日2007-01-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
5K7R
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BU of 5k7r by Molmil
MicroED structure of trypsin at 1.7 A resolution
分子名称: CALCIUM ION, Cationic trypsin
著者de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
登録日2016-05-26
公開日2017-04-05
最終更新日2024-10-09
実験手法ELECTRON CRYSTALLOGRAPHY (1.7 Å)
主引用文献Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
2ONV
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BU of 2onv by Molmil
Crystal Structure of the amyloid-fibril forming peptide GGVVIA derived from the Alzheimer's amyloid Abeta (Abeta37-42).
分子名称: amyloid-fibril forming peptide GGVVIA derived from the Alzheimer's amyloid Abeta
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-24
公開日2007-02-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
2ONW
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BU of 2onw by Molmil
Structure of SSTSSA, a fibril forming peptide from Bovine Pancreatic Ribonuclease (RNase A, residues 15-20)
分子名称: fibril forming peptide from Bovine Pancreatic Ribonuclease (RNase A)
著者Sambashivan, S, Sawaya, M.R, Eisenberg, D.
登録日2007-01-24
公開日2007-02-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
3BQ7
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BU of 3bq7 by Molmil
SAM domain of Diacylglycerol Kinase delta1 (E35G)
分子名称: Diacylglycerol kinase delta
著者Knight, M.J, Bowie, J.U, Sawaya, M.R.
登録日2007-12-19
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Regulation of Enzyme Localization by Polymerization: Polymer Formation by the SAM Domain of Diacylglycerol Kinase delta1
Structure, 16, 2008
2G38
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BU of 2g38 by Molmil
A PE/PPE Protein Complex from Mycobacterium tuberculosis
分子名称: MANGANESE (II) ION, PE FAMILY PROTEIN, PPE FAMILY PROTEIN
著者Strong, M, Sawaya, M.R, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2006-02-17
公開日2006-03-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.Usa, 103, 2006
7ICF
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BU of 7icf by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CDCL2 (0.1 MILLIMOLAR) (FOUR-DAY SOAK)
分子名称: CADMIUM ION, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ...
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
7ICP
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BU of 7icp by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF ZNCL2 (0.01 MILLIMOLAR)
分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ...
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta.
Biochemistry, 35, 1996
7ICL
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BU of 7icl by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (0.1 MILLIMOLAR)
分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ...
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta.
Biochemistry, 35, 1996
7ICV
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BU of 7icv by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (0.1 MILLIMOLAR) AND IN THE ABSENCE OF NACL
分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ...
著者Pelletier, H, Sawaya, M.R.
登録日1996-10-24
公開日1996-11-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta.
Biochemistry, 35, 1996
7ICU
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BU of 7icu by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CDCL2 (0.1 MILLIMOLAR)
分子名称: CADMIUM ION, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ...
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta.
Biochemistry, 35, 1996
7K3C
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BU of 7k3c by Molmil
SGMGGIT segment 58-64 from Keratin-8
分子名称: ETHANOL, SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, TRIETHYLENE GLYCOL
著者Murray, K.A, Sawaya, M.R, Eisenberg, D.S.
登録日2020-09-11
公開日2021-11-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Nat.Struct.Mol.Biol., 29, 2022
7K3Y
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BU of 7k3y by Molmil
GGYAGAS segment 52-58 from Keratin-8
分子名称: GGYAGAS segment 52-58 from the low complexity domain of Keratin-8
著者Murray, K.A, Sawaya, M.R, Eisenberg, D.S.
登録日2020-09-14
公開日2021-11-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Nat.Struct.Mol.Biol., 29, 2022
7K3X
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BU of 7k3x by Molmil
SGMGCIT segment 58-64 from Keratin-8 with G62C mutation
分子名称: ISOPROPYL ALCOHOL, SGMGCIT segment 58-64 from Keratin-8 with G62C mutation
著者Murray, K.A, Sawaya, M.R, Eisenberg, D.S.
登録日2020-09-14
公開日2021-11-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.705 Å)
主引用文献Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Nat.Struct.Mol.Biol., 29, 2022
3MLI
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BU of 3mli by Molmil
2ouf-ds, a disulfide-linked dimer of Helicobacter pylori protein HP0242
分子名称: CALCIUM ION, Putative uncharacterized protein
著者King, N.P, Sawaya, M.R, Jacobitz, A.W, Yeates, T.O.
登録日2010-04-16
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and folding of a designed knotted protein.
Proc.Natl.Acad.Sci.USA, 107, 2010
6VW2
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BU of 6vw2 by Molmil
Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils
分子名称: Islet amyloid polypeptide (SUMO-tagged)
著者Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
登録日2020-02-18
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils.
Nat.Struct.Mol.Biol., 27, 2020
5V5C
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BU of 5v5c by Molmil
VQIINK, Structure of the amyloid-spine from microtubule associated protein tau Repeat 2
分子名称: Microtubule-associated protein tau
著者Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R.
登録日2017-03-14
公開日2018-02-07
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.25 Å)
主引用文献Structure-based inhibitors of tau aggregation.
Nat Chem, 10, 2018
7ICJ
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BU of 7icj by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CUCL2 (0.1 MILLIMOLAR)
分子名称: COPPER (II) ION, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*G)-3'), ...
著者Pelletier, H, Sawaya, M.R.
登録日1996-04-19
公開日1996-11-15
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
6C88
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BU of 6c88 by Molmil
STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
分子名称: GLYCEROL, VAL-ALA-VAL-HIS-VAL-PHE
著者Saelices, L, Sawaya, M.R, Eisenberg, D.S.
登録日2018-01-24
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018

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件を2024-10-09に公開中

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