5RKK
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![BU of 5rkk by Molmil](/molmil-images/mine/5rkk) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z275181224 | Descriptor: | N-[(1-ethyl-1H-pyrazol-4-yl)methyl]pyridine-3-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RJT
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![BU of 5rjt by Molmil](/molmil-images/mine/5rjt) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z404993336 | Descriptor: | 5-methyl-N-(1-methyl-1H-pyrazol-4-yl)-1,2-oxazole-3-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.169 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RK8
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![BU of 5rk8 by Molmil](/molmil-images/mine/5rk8) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z53116498 | Descriptor: | 3-(2-methyl-1H-benzimidazol-1-yl)propanamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.272 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKJ
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![BU of 5rkj by Molmil](/molmil-images/mine/5rkj) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z373768898 | Descriptor: | N-(1-ethyl-1H-pyrazol-4-yl)cyclopentanecarboxamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RJR
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![BU of 5rjr by Molmil](/molmil-images/mine/5rjr) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z45705015 | Descriptor: | PH-interacting protein, ~{N}-[2-(4-fluorophenyl)ethyl]methanesulfonamide | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RK7
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![BU of 5rk7 by Molmil](/molmil-images/mine/5rk7) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z31721097 | Descriptor: | PH-interacting protein, ethyl morpholine-4-carboxylate | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.304 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKP
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![BU of 5rkp by Molmil](/molmil-images/mine/5rkp) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1079512010 | Descriptor: | 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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1G1B
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![BU of 1g1b by Molmil](/molmil-images/mine/1g1b) | CHORISMATE LYASE (WILD-TYPE) WITH BOUND PRODUCT | Descriptor: | CHORISMATE LYASE, P-HYDROXYBENZOIC ACID | Authors: | Gallagher, D.T, Mayhew, M, Holden, M.J, Kim, K.J, Howard, A, Vilker, V.L. | Deposit date: | 2000-10-11 | Release date: | 2001-04-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The crystal structure of chorismate lyase shows a new fold and a tightly retained product. Proteins, 44, 2001
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5RJU
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![BU of 5rju by Molmil](/molmil-images/mine/5rju) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z57261895 | Descriptor: | 2-cyclohexyl-N-(4H-1,2,4-triazol-4-yl)acetamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKA
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![BU of 5rka by Molmil](/molmil-images/mine/5rka) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z126932614 | Descriptor: | 2-[(methylsulfonyl)methyl]-1H-benzimidazole, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKO
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![BU of 5rko by Molmil](/molmil-images/mine/5rko) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z30620520 | Descriptor: | PH-interacting protein, cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKY
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![BU of 5rky by Molmil](/molmil-images/mine/5rky) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1796014543 | Descriptor: | 1-[(2-fluorophenyl)methyl]-N-methylcyclopropane-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RJZ
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![BU of 5rjz by Molmil](/molmil-images/mine/5rjz) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z755044716 | Descriptor: | N-ethyl-1H-1,2,3-triazole-4-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.275 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKF
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![BU of 5rkf by Molmil](/molmil-images/mine/5rkf) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1674937530 | Descriptor: | 2-(1-ethyl-1H-pyrazol-4-yl)ethan-1-ol, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.264 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKV
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![BU of 5rkv by Molmil](/molmil-images/mine/5rkv) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z56877838 | Descriptor: | 2-(4-ethoxyphenyl)ethanoic acid, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.277 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RJN
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![BU of 5rjn by Molmil](/molmil-images/mine/5rjn) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00024673 | Descriptor: | 4-bromo-1-(2-methoxyethyl)-1H-pyrazole, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.435 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RK4
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![BU of 5rk4 by Molmil](/molmil-images/mine/5rk4) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z56791867 | Descriptor: | N,N-diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.284 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKH
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![BU of 5rkh by Molmil](/molmil-images/mine/5rkh) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z31432917 | Descriptor: | 2-(4-methylphenoxy)-1-(4-methylpiperazin-4-ium-1-yl)ethanone, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.252 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5RKX
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![BU of 5rkx by Molmil](/molmil-images/mine/5rkx) | PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1324080698 | Descriptor: | 3-fluoro-5-methylbenzene-1-sulfonamide, PH-interacting protein | Authors: | Grosjean, H, Aimon, A, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Biggin, P.C. | Deposit date: | 2020-06-02 | Release date: | 2020-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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5TB6
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![BU of 5tb6 by Molmil](/molmil-images/mine/5tb6) | Structure of bromodomain of CREBBP with a pyrazolo[4,3-c]pyridin fragment | Descriptor: | 1,2-ETHANEDIOL, 1-(3-phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl)propan-1-one, CREB-binding protein | Authors: | Filippakopoulos, P, Picaud, S, Knapp, S, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Structural Genomics Consortium (SGC) | Deposit date: | 2016-09-11 | Release date: | 2016-10-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening. ACS Med Chem Lett, 7, 2016
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2A72
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![BU of 2a72 by Molmil](/molmil-images/mine/2a72) | Structure of the regulator of G-protein signaling domain of RGS7 | Descriptor: | CHLORIDE ION, Regulator of G-protein signalling 7 | Authors: | Schoch, G.A, Johansson, C, Phillips, C, Debreczeni, J, Smee, C, Elkins, J.M, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Gileadi, O, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2005-07-04 | Release date: | 2005-07-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1MXF
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![BU of 1mxf by Molmil](/molmil-images/mine/1mxf) | Crystal Structure of Inhibitor Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi | Descriptor: | METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE 2 | Authors: | Schormann, N, Pal, B, Senkovich, O, Carson, M, Howard, A, Smith, C, Delucas, L, Chattopadhyay, D. | Deposit date: | 2002-10-02 | Release date: | 2003-10-14 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor. J.Struct.Biol., 152, 2005
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2WZS
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![BU of 2wzs by Molmil](/molmil-images/mine/2wzs) | Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with Mannoimidazole | Descriptor: | (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Zhu, Y, Suits, M.D.L, Thompson, A, Chavan, S, Dinev, Z, Dumon, C, Smith, N, Moremen, K.W, Xiang, Y, Siriwardena, A, Williams, S.J, Gilbert, H.J, Davies, G.J. | Deposit date: | 2009-12-02 | Release date: | 2009-12-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont. Nat.Chem.Biol., 6, 2010
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2W2J
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![BU of 2w2j by Molmil](/molmil-images/mine/2w2j) | Crystal structure of the human carbonic anhydrase related protein VIII | Descriptor: | CARBONIC ANHYDRASE-RELATED PROTEIN, CHLORIDE ION, GLYCEROL, ... | Authors: | Kramm, A, Muniz, J.R.C, Picaud, S.S, von Delft, F, Pilka, E.S, Yue, W.W, King, O.N.F, Kochan, G, Pike, A.C.W, Filippakopoulos, P, Arrowsmith, C, Wikstrom, M, Edwards, A, Bountra, C, Oppermann, U. | Deposit date: | 2008-10-31 | Release date: | 2009-02-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Human Carbonic Anhydrase-Related Protein Viii Reveals the Basis for Catalytic Silencing. Proteins, 76, 2009
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1MWQ
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![BU of 1mwq by Molmil](/molmil-images/mine/1mwq) | Structure of HI0828, a Hypothetical Protein from Haemophilus influenzae with a Putative Active-Site Phosphohistidine | Descriptor: | CACODYLATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Willis, M.A, Krajewski, W, Chalamasetty, V.R, Reddy, P, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | Deposit date: | 2002-09-30 | Release date: | 2003-11-25 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | Structure of YciI from Haemophilus influenzae (HI0828) reveals a ferredoxin-like alpha/beta-fold with a histidine/aspartate centered catalytic site Proteins, 59, 2005
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