1W0G
 
 | | Crystal structure of human cytochrome P450 3A4 | | Descriptor: | CYTOCHROME P450 3A4, METYRAPONE, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Williams, P.A, Cosme, J, Vinkovic, D.M, Ward, A, Angove, H.C, Day, P.J, Vonrhein, C, Tickle, I.J, Jhoti, H. | | Deposit date: | 2004-06-03 | | Release date: | 2004-07-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone
Science, 305, 2004
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1W0F
 | | Crystal structure of human cytochrome P450 3A4 | | Descriptor: | CYTOCHROME P450 3A4, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Williams, P.A, Cosme, J, Vinkovic, D.M, Ward, A, Angove, H.C, Day, P.J, Vonrhein, C, Tickle, I.J, Jhoti, H. | | Deposit date: | 2004-06-03 | | Release date: | 2004-07-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone
Science, 305, 2004
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8TP5
 | | H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1E04 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ... | | Authors: | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | | Deposit date: | 2023-08-04 | | Release date: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination.
Biorxiv, 2023
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8T4A
 | | MD65 N332-GT5 SOSIP in complex with RM_N332_36 Fab and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2023-06-08 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
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8T4K
 | | MD64 N332-GT5 SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD64 N332-GT5 SOSIP gp120, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2023-06-09 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
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8T4L
 | | MD65 N332-GT5 SOSIP in complex with RM_N332_07 Fab and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2023-06-09 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
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7TQU
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7TQS
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7TQT
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8SW7
 | | BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 Boost 2 gp120, BG505 Boost 2 gp41, ... | | Authors: | Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B. | | Deposit date: | 2023-05-17 | | Release date: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Focusing antibody responses to the fusion peptide in rhesus macaques.
Biorxiv, 2023
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8SWV
 | | BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody IF1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IF1 Heavy Chain, ... | | Authors: | Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B. | | Deposit date: | 2023-05-19 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Focusing antibody responses to the fusion peptide in rhesus macaques
To Be Published
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8T4D
 | | MD65 N332-GT5 SOSIP in complex with RM_N332_08 Fab and RM20A3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MD65 N332-GT5 SOSIP gp120, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2023-06-09 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Science, 384, 2024
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8U1S
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8U1C
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8U1Q
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7N5D
 | | Composite Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN | | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | | Deposit date: | 2021-06-05 | | Release date: | 2022-02-16 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
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7N5E
 | | Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN | | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | | Deposit date: | 2021-06-05 | | Release date: | 2022-02-16 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
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8SWW
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8T57
 | | Structure of mechanically activated ion channel OSCA2.3 in peptidiscs | | Descriptor: | CHOLESTEROL, CSC1-like protein HYP1, PALMITIC ACID | | Authors: | Jojoa-Cruz, S, Burendei, B, Lee, W.H, Ward, A.B. | | Deposit date: | 2023-06-12 | | Release date: | 2023-12-27 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain.
Structure, 32, 2024
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8T56
 | | Structure of mechanically activated ion channel OSCA1.2 in peptidiscs | | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Burendei, B, Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | | Deposit date: | 2023-06-12 | | Release date: | 2023-12-27 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain.
Structure, 32, 2024
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7N5G
 | | Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Up' conformation in GDN | | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | | Deposit date: | 2021-06-05 | | Release date: | 2022-02-16 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
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7N5F
 | | Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Down' conformation in GDN | | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | | Deposit date: | 2021-06-05 | | Release date: | 2022-02-16 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
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8SWX
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1OG5
 | | Structure of human cytochrome P450 CYP2C9 | | Descriptor: | CYTOCHROME P450 2C9, HEME C, S-WARFARIN | | Authors: | Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. | | Deposit date: | 2003-04-24 | | Release date: | 2003-07-17 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin
Nature, 424, 2003
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1OG2
 | | Structure of human cytochrome P450 CYP2C9 | | Descriptor: | CYTOCHROME P450 2C9, HEME C | | Authors: | Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. | | Deposit date: | 2003-04-23 | | Release date: | 2003-07-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin
Nature, 424, 2003
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