7VFU
 
 | | Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to ziconotide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Dong, Y, Gao, Y, Wang, Y, Zhao, Y. | | 登録日 | 2021-09-13 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Closed-state inactivation and pore-blocker modulation mechanisms of human Ca V 2.2.
Cell Rep, 37, 2021
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7VFW
 | | Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to CaV2.2-blocker1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyloxan-4-yl)pyrazole, CALCIUM ION, ... | | 著者 | Dong, Y, Gao, Y, Wang, Y, Zhao, Y. | | 登録日 | 2021-09-13 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Closed-state inactivation and pore-blocker modulation mechanisms of human Ca V 2.2.
Cell Rep, 37, 2021
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7VFS
 | | Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, apo state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Dong, Y, Gao, Y, Wang, Y, Zhao, Y. | | 登録日 | 2021-09-13 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Closed-state inactivation and pore-blocker modulation mechanisms of human Ca V 2.2.
Cell Rep, 37, 2021
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1YT3
 | | Crystal Structure of Escherichia coli RNase D, an exoribonuclease involved in structured RNA processing | | 分子名称: | Ribonuclease D, SULFATE ION, ZINC ION | | 著者 | Zuo, Y, Wang, Y, Malhotra, A. | | 登録日 | 2005-02-09 | | 公開日 | 2005-08-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of Escherichia coli RNase D, an Exoribonuclease Involved in Structured RNA Processing
Structure, 13, 2005
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5EZK
 | | RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex. | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Darbari, V.C, Yang, Y, Lu, D, Zhang, N, Glyde, R, Wang, Y, Murakami, K.S, Buck, M, Zhang, X. | | 登録日 | 2015-11-26 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (8.5 Å) | | 主引用文献 | TRANSCRIPTION. Structures of the RNA polymerase- Sigma 54 reveal new and conserved regulatory strategies.
Science, 349, 2015
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2QDW
 | | Structure of Cu(I) form of the M51A mutant of amicyanin | | 分子名称: | Amicyanin, COPPER (I) ION, PHOSPHATE ION | | 著者 | Ma, J.K, Wang, Y, Carrell, C.J, Mathews, F.S, Davidson, V.L. | | 登録日 | 2007-06-21 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | | 主引用文献 | A single methionine residue dictates the kinetic mechanism of interprotein electron transfer from methylamine dehydrogenase to amicyanin.
Biochemistry, 46, 2007
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6NOC
 | | Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y) in complex with 8-nt RNA | | 分子名称: | Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3') | | 著者 | McCann, K, Wang, Y, Qiu, C, Hall, T.M.T. | | 登録日 | 2019-01-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.849 Å) | | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
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1SVK
 | | Structure of the K180P mutant of Gi alpha subunit bound to AlF4 and GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | | 著者 | Thomas, C.J, Du, X, Li, P, Wang, Y, Ross, E.M, Sprang, S.R. | | 登録日 | 2004-03-29 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit.
Proc.Natl.Acad.Sci.USA, 101, 2004
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6NNG
 | | Tubulin-RB3_SLD-TTL in complex with compound DJ95 | | 分子名称: | 2-(1H-indol-6-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | | 登録日 | 2019-01-15 | | 公開日 | 2019-07-10 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | | 主引用文献 | Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy.
Mol.Pharmacol., 96, 2019
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1TCS
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1QJL
 | | METALLOTHIONEIN MTA FROM SEA URCHIN (BETA DOMAIN) | | 分子名称: | CADMIUM ION, METALLOTHIONEIN | | 著者 | Riek, R, Precheur, B, Wang, Y, Mackay, E.A, Wider, G, Guntert, P, Liu, A, Kaegi, J.H.R, Wuthrich, K. | | 登録日 | 1999-06-24 | | 公開日 | 1999-08-31 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA.
J. Mol. Biol., 291, 1999
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1QJK
 | | Metallothionein MTA from sea urchin (alpha domain) | | 分子名称: | CADMIUM ION, METALLOTHIONEIN | | 著者 | Riek, R, Precheur, B, Wang, Y, Mackay, E.A, Wider, G, Guntert, P, Liu, A, Kaegi, J.H.R, Wuthrich, K. | | 登録日 | 1999-06-24 | | 公開日 | 1999-08-31 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA.
J. Mol. Biol., 291, 1999
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6NOF
 | | Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y, Q367S) in complex with 8-nt RNA | | 分子名称: | 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3') | | 著者 | McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T. | | 登録日 | 2019-01-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
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1RE5
 | | Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-carboxy-cis,cis-muconate cycloisomerase, CITRIC ACID | | 著者 | Yang, J, Wang, Y, Woolridge, E.M, Petsko, G.A, Kozarich, J.W, Ringe, D. | | 登録日 | 2003-11-06 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of 3-Carboxy-cis,cis-muconate Lactonizing Enzyme from Pseudomonas putida, a Fumarase Class II Type Cycloisomerase: Enzyme Evolution in Parallel Pathways.
Biochemistry, 43, 2004
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8GRX
 | | APOE4 receptor in complex with APOE4 NTD | | 分子名称: | Apolipoprotein E, Leukocyte immunoglobulin-like receptor subfamily A member 6 | | 著者 | Zhou, J, Wang, Y, Huang, G, Shi, Y. | | 登録日 | 2022-09-02 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | LilrB3 is a putative cell surface receptor of APOE4.
Cell Res., 33, 2023
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1RXT
 | | Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase. | | 分子名称: | COBALT (II) ION, Glycylpeptide N-tetradecanoyltransferase 1, SULFATE ION | | 著者 | Yang, J, Wang, Y, Frey, G, Abeles, R.H, Petsko, G.A, Ringe, D. | | 登録日 | 2003-12-18 | | 公開日 | 2005-04-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase
To be Published
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6NOH
 | | Crystal structure of FBF-2 repeat 5 mutant (C363S, R364Y, Q367S) in complex with 8-nt RNA | | 分子名称: | 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3') | | 著者 | McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T. | | 登録日 | 2019-01-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
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1S8K
 | | Solution Structure of BmKK4, A Novel Potassium Channel Blocker from Scorpion Buthus martensii Karsch, 25 structures | | 分子名称: | Toxin BmKK4 | | 著者 | Zhang, N, Chen, X, Li, M, Cao, C, Wang, Y, Hu, G, Wu, H. | | 登録日 | 2004-02-02 | | 公開日 | 2005-02-08 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of BmKK4, the first member of subfamily alpha-KTx 17 of scorpion toxins
Biochemistry, 43, 2004
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6P7H
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1T3X
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1T3Y
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1RD6
 | | Crystal Structure of S. Marcescens Chitinase A Mutant W167A | | 分子名称: | Chitinase A | | 著者 | Aronson, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L. | | 登録日 | 2003-11-05 | | 公開日 | 2004-12-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Mutation of a conserved tryptophan in the chitin-binding cleft of Serratia marcescens chitinase A enhances transglycosylation.
Biosci.Biotechnol.Biochem., 70, 2006
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2QTU
 | | Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand | | 分子名称: | (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol, Estrogen receptor beta | | 著者 | Richardson, T.I, Dodge, J.A, Wang, Y, Durbin, J.D, Krishnan, V, Norman, B.H. | | 登録日 | 2007-08-02 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies.
Bioorg.Med.Chem.Lett., 17, 2007
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2QDV
 | | Structure of the Cu(II) form of the M51A mutant of amicyanin | | 分子名称: | Amicyanin, COPPER (II) ION, PHOSPHATE ION | | 著者 | Carrell, C.J, Ma, J.K, Wang, Y, Davidson, V.L, Mathews, F.S. | | 登録日 | 2007-06-21 | | 公開日 | 2007-12-11 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | | 主引用文献 | A single methionine residue dictates the kinetic mechanism of interprotein electron transfer from methylamine dehydrogenase to amicyanin.
Biochemistry, 46, 2007
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2QE4
 | | Estrogen receptor alpha ligand-binding domain in complex with a benzopyran agonist | | 分子名称: | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, Estrogen receptor | | 著者 | Norman, B.H, Richardson, T.I, Dodge, J.A, Pfeifer, L.A, Durst, G.L, Wang, Y, Durbin, J.D, Krishnan, V, Dinn, S.R, Liu, S.Q, Reilly, J.E, Ryter, K.T. | | 登録日 | 2007-06-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring.
Bioorg.Med.Chem.Lett., 17, 2007
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