7E2G
 
 | | Cryo-EM structure of hDisp1NNN-3C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1,Protein dispatched homolog 1 | | Authors: | Li, W, Wang, L, Gong, X. | | Deposit date: | 2021-02-05 | | Release date: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
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2MY9
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4OHE
 | | LEOPARD Syndrome-Associated SHP2/G464A mutant | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11 | | Authors: | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | Deposit date: | 2014-01-17 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.506 Å) | | Cite: | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
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4OHD
 | | LEOPARD Syndrome-Associated SHP2/A461T mutant | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11 | | Authors: | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | Deposit date: | 2014-01-17 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
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4OHI
 | | LEOPARD Syndrome-Associated SHP2/Q510E mutant | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11 | | Authors: | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | Deposit date: | 2014-01-17 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
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4OHL
 | | LEOPARD Syndrome-Associated SHP2/T468M mutant | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11 | | Authors: | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | Deposit date: | 2014-01-17 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
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4OHH
 | | LEOPARD Syndrome-Associated SHP2/Q506P mutant | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11 | | Authors: | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | Deposit date: | 2014-01-17 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
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7XC6
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2G9F
 | | Crystal structure of intein-tagged mouse PNGase C-terminal domain | | Descriptor: | CHLORIDE ION, GLYCEROL, peptide N-glycanase | | Authors: | Zhou, X, Zhao, G, Wang, L, Li, G, Lennarz, W.J, Schindelin, H. | | Deposit date: | 2006-03-06 | | Release date: | 2006-10-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2H53
 | | Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26 | | Descriptor: | small heat shock protein Hsp26 | | Authors: | White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R. | | Deposit date: | 2006-05-25 | | Release date: | 2006-08-01 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (11.5 Å) | | Cite: | Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
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2H50
 | | Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26 | | Descriptor: | small heat shock protein Hsp26 | | Authors: | White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R. | | Deposit date: | 2006-05-25 | | Release date: | 2006-08-01 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (10.8 Å) | | Cite: | Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
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2HPL
 | | Crystal structure of the mouse p97/PNGase complex | | Descriptor: | C-terminal of mouse p97/VCP, PNGase | | Authors: | Zhao, G, Zhou, X, Wang, L, Li, G, Lennarz, W, Schindelin, H. | | Deposit date: | 2006-07-17 | | Release date: | 2007-05-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2HPJ
 | | Crystal structure of the PUB domain of mouse PNGase | | Descriptor: | GLYCEROL, PNGase | | Authors: | Zhao, G, Zhou, X, Wang, L, Li, G, Lennarz, W, Schindelin, H. | | Deposit date: | 2006-07-17 | | Release date: | 2007-05-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2I74
 | | Crystal structure of mouse Peptide N-Glycanase C-terminal domain in complex with mannopentaose | | Descriptor: | ACETATE ION, GLYCEROL, PNGase, ... | | Authors: | Zhou, X, Zhao, G, Wang, L, Li, G, Lennarz, W.J, Schindelin, H. | | Deposit date: | 2006-08-30 | | Release date: | 2006-10-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2IBJ
 | | Structure of House Fly Cytochrome B5 | | Descriptor: | Cytochrome b5, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L. | | Deposit date: | 2006-09-11 | | Release date: | 2007-02-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Comparison of cytochromes b(5) from insects and vertebrates.
Proteins, 67, 2007
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2I89
 | | Structure of septuple mutant of Rat Outer Mitochondrial Membrane Cytochrome B5 | | Descriptor: | Cytochrome b5 type B, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L, Sun, N. | | Deposit date: | 2006-09-01 | | Release date: | 2006-10-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A histidine/tryptophan pi-stacking interaction stabilizes the heme-independent folding core of microsomal apocytochrome b5 relative to that of mitochondrial apocytochrome b5.
Biochemistry, 45, 2006
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2J9I
 | | Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re- engineering for a tissue-specific role in the vertebrate eye lens. | | Descriptor: | GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1 | | Authors: | Wyatt, K, White, H.E, Wang, L, Bateman, O.A, Slingsby, C, Orlova, E.V, Wistow, G. | | Deposit date: | 2006-11-09 | | Release date: | 2006-12-13 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (17 Å) | | Cite: | Lengsin is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-Engineered by Evolution for a Role in the Vertebrate Lens.
Structure, 14, 2006
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2JAS
 | | Structure of deoxyadenosine kinase from M.mycoides with bound dATP | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DEOXYGUANOSINE KINASE, MAGNESIUM ION | | Authors: | Welin, M, Wang, L, Eriksson, S, Eklund, H. | | Deposit date: | 2006-11-30 | | Release date: | 2007-01-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity.
J.Mol.Biol., 366, 2007
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2JA1
 | | Thymidine kinase from B. cereus with TTP bound as phosphate donor. | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H. | | Deposit date: | 2006-11-17 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
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2J9R
 | | Thymidine kinase from B. anthracis in complex with dT. | | Descriptor: | PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ... | | Authors: | Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H. | | Deposit date: | 2006-11-15 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
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2JAT
 | | Structure of deoxyadenosine kinase from M.mycoides with products dcmp and a flexible dcdp bound | | Descriptor: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, DEOXYGUANOSINE KINASE, MAGNESIUM ION, ... | | Authors: | Welin, M, Wang, L, Eriksson, S, Eklund, H. | | Deposit date: | 2006-11-30 | | Release date: | 2007-01-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity.
J.Mol.Biol., 366, 2007
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2JAQ
 | | Structure of deoxyadenosine kinase from M. mycoides with bound dCTP | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DEOXYGUANOSINE KINASE | | Authors: | Welin, M, Wang, L, Eriksson, S, Eklund, H. | | Deposit date: | 2006-11-30 | | Release date: | 2007-01-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity.
J.Mol.Biol., 366, 2007
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2MI2
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2M5N
 | | Atomic-resolution structure of a cross-beta protofilament | | Descriptor: | Transthyretin | | Authors: | Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M. | | Deposit date: | 2013-02-27 | | Release date: | 2013-07-17 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Atomic structure and hierarchical assembly of a cross-{beta} amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2M5M
 | | Atomic-resolution structure of a triplet cross-beta amyloid fibril | | Descriptor: | Transthyretin | | Authors: | Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M. | | Deposit date: | 2013-02-27 | | Release date: | 2013-12-04 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (12.2 Å), SOLID-STATE NMR | | Cite: | Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
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