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PDB: 1116 件

3HYM
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Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26-APC6 structure
分子名称: Anaphase-promoting complex subunit CDC26, Cell division cycle protein 16 homolog
著者Wang, J, Dye, B.T, Rajashankar, K.R, Kurinov, I, Schulman, B.A.
登録日2009-06-22
公開日2009-08-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure.
Nat.Struct.Mol.Biol., 16, 2009
7X45
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Grass carp interferon gamma related
分子名称: Interferon gamma
著者Wang, J, Zou, J, Zhu, X.
登録日2022-03-02
公開日2022-09-14
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Novel Dimeric Architecture of an IFN-gamma-Related Cytokine Provides Insights into Subfunctionalization of Type II IFNs in Teleost Fish.
J Immunol., 209, 2022
5ZCJ
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Crystal structure of complex
分子名称: TP53-binding protein 1, Tudor-interacting repair regulator protein
著者Wang, J, Yuan, Z, Cui, Y, Xie, R, Wang, M, Ma, Y, Yu, X, Liu, X.
登録日2018-02-17
公開日2018-06-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Crystal structure of complex
To Be Published
5YYS
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Cryo-EM structure of L-fucokinase, GDP-fucose pyrophosphorylase (FKP)in Bacteroides fragilis
分子名称: L-fucokinase, L-fucose-1-P guanylyltransferase
著者Wang, J, Hu, H, Liu, Y, Zhou, Q, Wu, P, Yan, N, Wang, H.W, Wu, J.W, Sun, L.
登録日2017-12-11
公開日2018-12-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of L-fucokinase/GDP-fucose pyrophosphorylase (FKP) in Bacteroides fragilis.
Protein Cell, 10, 2019
7DPM
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BU of 7dpm by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-12-20
公開日2021-02-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.304 Å)
主引用文献Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV.
Mabs, 13, 2021
7DQA
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BU of 7dqa by Molmil
Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ...
著者Wang, J, Lan, J, Wang, X.Q, Wang, H.W.
登録日2020-12-22
公開日2021-12-29
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM
Biophys Rep, 7, 2022
6J5S
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BU of 6j5s by Molmil
Crystal structure of human HINT1 mutant complexing with AP5A
分子名称: BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ETHANESULFONIC ACID, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2019-01-11
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
6J53
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Crystal structure of human HINT1 complexing with ATP
分子名称: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2019-01-10
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
6J58
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Crystal structure of human HINT1 complexing with AP4A
分子名称: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2019-01-10
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.521 Å)
主引用文献Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
6J64
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Crystal structure of human HINT1 mutant complexing with AP4A
分子名称: 2-AMINOETHANESULFONIC ACID, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2019-01-14
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
6J5Z
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Crystal structure of human HINT1 mutant complexing with AP3A
分子名称: ADENOSINE, ETHANESULFONIC ACID, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2019-01-12
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
6J65
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Crystal structure of human HINT1 mutant complexing with AP4A II
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2019-01-14
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10, 2019
4EQG
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Crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from human complexed with Ala-AMS
分子名称: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2012-04-18
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Side chain independent recognition of aminoacyl adenylates by the hint1 transcription suppressor.
J.Phys.Chem.B, 116, 2012
4EQE
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Crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from human complexed with Lys-AMS
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2012-04-18
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Side chain independent recognition of aminoacyl adenylates by the hint1 transcription suppressor.
J.Phys.Chem.B, 116, 2012
4EQH
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BU of 4eqh by Molmil
Crystal structure of histidine triad nucleotide-binding protein 1 (HINT1) from human complexed with Trp-AMS
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(L-TRYPTOPHYLAMINO)SULFONYL]ADENOSINE, Histidine triad nucleotide-binding protein 1
著者Wang, J, Fang, P, Guo, M.
登録日2012-04-18
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.668 Å)
主引用文献Side chain independent recognition of aminoacyl adenylates by the hint1 transcription suppressor.
J.Phys.Chem.B, 116, 2012
5TMF
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BU of 5tmf by Molmil
Re-refinement of thermus thermophilus RNA polymerase
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Wang, J.
登録日2016-10-12
公開日2016-11-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献On the validation of crystallographic symmetry and the quality of structures.
Protein Sci., 24, 2015
4L52
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Crystal Structure of 1-(4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}piperidin-1-yl)ethan-1-one bound to TAK1-TAB1
分子名称: 1-(4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}piperidin-1-yl)ethanone, Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera
著者Wang, J, Hornberger, K.R, Crew, A.P, Jestel, A, Maskos, K, Moertl, M.
登録日2013-06-10
公開日2013-07-03
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1.
Bioorg.Med.Chem.Lett., 23, 2013
4L3P
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BU of 4l3p by Molmil
Crystal Structure of 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine bound to TAK1-TAB1
分子名称: 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine, Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera
著者Wang, J, Hornberger, K.R, Crew, A.P, Steinbacher, S, Maskos, K, Moertl, M.
登録日2013-06-06
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1.
Bioorg.Med.Chem.Lett., 23, 2013
1JOR
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Ensemble structures for unligated Staphylococcal nuclease-H124L
分子名称: staphylococcal nuclease
著者Wang, J, Truckses, D.M, Abildgaard, F, Dzakula, Z, Zolnai, Z, Markley, J.L.
登録日2001-07-30
公開日2001-08-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of staphylococcal nuclease from multidimensional, multinuclear NMR: nuclease-H124L and its ternary complex with Ca2+ and thymidine-3',5'-bisphosphate.
J.Biomol.NMR, 10, 1997
7WVZ
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BU of 7wvz by Molmil
CalA3_modular PKS_KS-AT-DH-KR
分子名称: Beta-ketoacyl-acyl-carrier-protein synthase I
著者Wang, J, Wang, Z.
登録日2022-02-12
公開日2023-02-22
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献C-N bond formation by a polyketide synthase.
Nat Commun, 14, 2023
7XVK
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Modularity of Phytophthora effectors enables host mimicry of a principal phosphatase
分子名称: 1,2-ETHANEDIOL, RxLR effector protein PSR2, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
著者Wang, J, Wang, Y.
登録日2022-05-24
公開日2023-07-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Pathogen protein modularity enables elaborate mimicry of a host phosphatase.
Cell, 186, 2023
7XVI
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pathogen effectors which are essential to cause plant disease by manipulating cellular processes in the host
分子名称: 1,2-ETHANEDIOL, CADMIUM ION, PITG_15142
著者Wang, J, Wang, Y.
登録日2022-05-23
公開日2023-07-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Pathogen protein modularity enables elaborate mimicry of a host phosphatase.
Cell, 186, 2023
4LR3
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Crystal structure of E. coli YfbU at 2.5 A resolution
分子名称: MAGNESIUM ION, PHOSPHATE ION, protein YfbU
著者Wang, J, Wing, R.A.
登録日2013-07-19
公開日2014-04-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Diamonds in the rough: a strong case for the inclusion of weak-intensity X-ray diffraction data.
Acta Crystallogr.,Sect.D, 70, 2014
4L53
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Crystal Structure of (1R,4R)-4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-chlorofuro[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}cyclohexan-1-ol bound to TAK1-TAB1
分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, ...
著者Wang, J, Hornberger, K.R, Crew, A.P, Jestel, A, Maskos, K, Moertl, M.
登録日2013-06-10
公開日2013-07-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics.
Bioorg.Med.Chem.Lett., 23, 2013
1K0L
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Pseudomonas aeruginosa phbh R220Q free of p-OHB
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, SULFATE ION, ...
著者Wang, J, Ortiz-Maldonado, M, Entsch, B, Ballou, D, Gatti, D.L.
登録日2001-09-19
公開日2002-02-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase.
Proc.Natl.Acad.Sci.USA, 99, 2002

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