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PDB: 1358 件

6LYW
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BU of 6lyw by Molmil
Structural insight into the biological functions of Arabidopsis thaliana ACHT1
分子名称: GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ...
著者Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M.
登録日2020-02-16
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
8HQN
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BU of 8hqn by Molmil
Activation mechanism of GPR132 by 9(S)-HODE
分子名称: (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
登録日2022-12-13
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
8HQE
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BU of 8hqe by Molmil
Cryo-EM structure of the apo-GPR132-Gi
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
登録日2022-12-13
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
8HQM
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BU of 8hqm by Molmil
Activation mechanism of GPR132 by NPGLY
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
登録日2022-12-13
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
8HVI
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BU of 8hvi by Molmil
Activation mechanism of GPR132 by compound NOX-6-7
分子名称: 3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
登録日2022-12-26
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
8IGA
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BU of 8iga by Molmil
Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Wang, J, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
6UZ6
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BU of 6uz6 by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and glutamate
分子名称: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
著者Wang, J.X, Furukawa, H.
登録日2019-11-14
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6UZX
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BU of 6uzx by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and UBP791
分子名称: (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCEROL, GLYCINE, ...
著者Wang, J.X, Furukawa, H.
登録日2019-11-15
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6UZG
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BU of 6uzg by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and homoquinolinic acid
分子名称: 3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
著者Wang, J.X, Furukawa, H.
登録日2019-11-15
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6UZR
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BU of 6uzr by Molmil
Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and homoquinolinic acid
分子名称: 3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCEROL, GLYCINE, ...
著者Wang, J.X, Furukawa, H.
登録日2019-11-15
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
6UZW
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BU of 6uzw by Molmil
Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and UBP791
分子名称: (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
著者Wang, J.X, Furukawa, H.
登録日2019-11-15
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
7K3J
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BU of 7k3j by Molmil
Crystal structure of dLC8 in complex with Panoramix TQT+TQ peptide
分子名称: Dynein light chain 1, cytoplasmic, Protein panoramix, ...
著者Wang, J, Patel, D.J.
登録日2020-09-11
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
8HW2
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BU of 8hw2 by Molmil
Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs
分子名称: ATP-binding cassette sub-family C member 3, Estradiol-17beta-glucuronide
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-28
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
8HW4
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BU of 8hw4 by Molmil
Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs
分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ATP-binding cassette sub-family C member 3
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-28
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
8HVH
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BU of 8hvh by Molmil
Cryo-EM structure of ABC transporter ABCC3
分子名称: ATP-binding cassette sub-family C member 3
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-26
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
6LYX
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BU of 6lyx by Molmil
Crystal structure of oxidized ACHT1
分子名称: GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ...
著者Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M.
登録日2020-02-16
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
7SJR
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BU of 7sjr by Molmil
Cryo-EM structure of AdnA-AdnB(W325A) in complex with DNA and AMPPNP
分子名称: DNA (70-MER), DNA helicase, IRON/SULFUR CLUSTER, ...
著者Wang, J, Warren, G.M, Shuman, S, Patel, D.J.
登録日2021-10-18
公開日2021-12-22
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB.
Nucleic Acids Res., 50, 2022
4NXB
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BU of 4nxb by Molmil
Crystal structure of iLOV-I486(2LT) at pH 7.0
分子名称: FLAVIN MONONUCLEOTIDE, Phototropin-2
著者Wang, J, Li, J, Liu, X.
登録日2013-12-09
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.561 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
7K3K
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BU of 7k3k by Molmil
Crystal structure of dLC8 in complex with Panoramix TQT peptide
分子名称: Dynein light chain 1, cytoplasmic, Protein panoramix
著者Wang, J, Patel, D.J.
登録日2020-09-11
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.415 Å)
主引用文献Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
7K3L
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BU of 7k3l by Molmil
Crystal structure of dLC8 in complex with Panoramix TQ peptide
分子名称: 1,2-ETHANEDIOL, Dynein light chain 1, cytoplasmic, ...
著者Wang, J, Patel, D.J.
登録日2020-09-11
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
6KP6
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BU of 6kp6 by Molmil
The structural study of mutation induced inactivation of Human muscarinic receptor M4
分子名称: Muscarinic acetylcholine receptor M4,GlgA glycogen synthase,Muscarinic acetylcholine receptor M4
著者Wang, J.J, Wu, M, Wu, L.J, Liu, Z.J, Hua, T.
登録日2019-08-14
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structural study of mutation-induced inactivation of human muscarinic receptor M4
Iucrj, 7, 2020
8HFS
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BU of 8hfs by Molmil
The structure of LcnA, LciA, and the man-PTS of Lactococcus lactis
分子名称: Bacteriocin lactococcin-A, Lactococcin-A immunity protein, Mannose-specific PTS system, ...
著者Wang, J.W.
登録日2022-11-12
公開日2023-02-08
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural Basis of the Mechanisms of Action and Immunity of Lactococcin A, a Class IId Bacteriocin.
Appl.Environ.Microbiol., 89, 2023
7MKK
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BU of 7mkk by Molmil
Crystal structure of Drosophila Panoramix in complex with Sov NTD
分子名称: Protein panoramix, Small ovary, isoform A
著者Wang, J, Patel, D.J.
登録日2021-04-24
公開日2022-02-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery.
Nat.Struct.Mol.Biol., 29, 2022
1LRN
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BU of 1lrn by Molmil
Aquifex aeolicus KDO8P synthase H185G mutant in complex with Cadmium
分子名称: CADMIUM ION, KDO-8-phosphate synthetase, PHOSPHATE ION
著者Wang, J, Duewel, H.S, Stuckey, J.A, Woodard, R.W, Gatti, D.L.
登録日2002-05-15
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Function of His185 in Aquifex aeolicus 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase
J.Mol.Biol., 324, 2002
1LRO
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BU of 1lro by Molmil
Aquifex aeolicus KDO8P synthase H185G mutant in complex with PEP and Cadmium
分子名称: CADMIUM ION, KDO-8-phosphate synthetase, PHOSPHATE ION, ...
著者Wang, J, Duewel, H.S, Stuckey, J.A, Woodard, R.W, Gatti, D.L.
登録日2002-05-15
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Function of His185 in Aquifex aeolicus 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase
J.Mol.Biol., 324, 2002

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件を2024-05-22に公開中

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