6LYW
| Structural insight into the biological functions of Arabidopsis thaliana ACHT1 | 分子名称: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | 著者 | Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M. | 登録日 | 2020-02-16 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
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8HQN
| Activation mechanism of GPR132 by 9(S)-HODE | 分子名称: | (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | 登録日 | 2022-12-13 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
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8HQE
| Cryo-EM structure of the apo-GPR132-Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | 登録日 | 2022-12-13 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
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8HQM
| Activation mechanism of GPR132 by NPGLY | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | 登録日 | 2022-12-13 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
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8HVI
| Activation mechanism of GPR132 by compound NOX-6-7 | 分子名称: | 3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | 登録日 | 2022-12-26 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
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8IGA
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6UZ6
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6UZX
| Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and UBP791 | 分子名称: | (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCEROL, GLYCINE, ... | 著者 | Wang, J.X, Furukawa, H. | 登録日 | 2019-11-15 | 公開日 | 2020-01-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nat Commun, 11, 2020
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6UZG
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6UZR
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6UZW
| Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and UBP791 | 分子名称: | (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ... | 著者 | Wang, J.X, Furukawa, H. | 登録日 | 2019-11-15 | 公開日 | 2020-01-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nat Commun, 11, 2020
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7K3J
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8HW2
| Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs | 分子名称: | ATP-binding cassette sub-family C member 3, Estradiol-17beta-glucuronide | 著者 | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | 登録日 | 2022-12-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket. Embo J., 42, 2023
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8HW4
| Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs | 分子名称: | 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ATP-binding cassette sub-family C member 3 | 著者 | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | 登録日 | 2022-12-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket. Embo J., 42, 2023
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8HVH
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6LYX
| Crystal structure of oxidized ACHT1 | 分子名称: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | 著者 | Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M. | 登録日 | 2020-02-16 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
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7SJR
| Cryo-EM structure of AdnA-AdnB(W325A) in complex with DNA and AMPPNP | 分子名称: | DNA (70-MER), DNA helicase, IRON/SULFUR CLUSTER, ... | 著者 | Wang, J, Warren, G.M, Shuman, S, Patel, D.J. | 登録日 | 2021-10-18 | 公開日 | 2021-12-22 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB. Nucleic Acids Res., 50, 2022
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4NXB
| Crystal structure of iLOV-I486(2LT) at pH 7.0 | 分子名称: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | 著者 | Wang, J, Li, J, Liu, X. | 登録日 | 2013-12-09 | 公開日 | 2014-09-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.561 Å) | 主引用文献 | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers. J.Am.Chem.Soc., 136, 2014
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7K3K
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7K3L
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6KP6
| The structural study of mutation induced inactivation of Human muscarinic receptor M4 | 分子名称: | Muscarinic acetylcholine receptor M4,GlgA glycogen synthase,Muscarinic acetylcholine receptor M4 | 著者 | Wang, J.J, Wu, M, Wu, L.J, Liu, Z.J, Hua, T. | 登録日 | 2019-08-14 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structural study of mutation-induced inactivation of human muscarinic receptor M4 Iucrj, 7, 2020
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8HFS
| The structure of LcnA, LciA, and the man-PTS of Lactococcus lactis | 分子名称: | Bacteriocin lactococcin-A, Lactococcin-A immunity protein, Mannose-specific PTS system, ... | 著者 | Wang, J.W. | 登録日 | 2022-11-12 | 公開日 | 2023-02-08 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural Basis of the Mechanisms of Action and Immunity of Lactococcin A, a Class IId Bacteriocin. Appl.Environ.Microbiol., 89, 2023
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7MKK
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1LRN
| Aquifex aeolicus KDO8P synthase H185G mutant in complex with Cadmium | 分子名称: | CADMIUM ION, KDO-8-phosphate synthetase, PHOSPHATE ION | 著者 | Wang, J, Duewel, H.S, Stuckey, J.A, Woodard, R.W, Gatti, D.L. | 登録日 | 2002-05-15 | 公開日 | 2002-11-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Function of His185 in Aquifex aeolicus 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase J.Mol.Biol., 324, 2002
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1LRO
| Aquifex aeolicus KDO8P synthase H185G mutant in complex with PEP and Cadmium | 分子名称: | CADMIUM ION, KDO-8-phosphate synthetase, PHOSPHATE ION, ... | 著者 | Wang, J, Duewel, H.S, Stuckey, J.A, Woodard, R.W, Gatti, D.L. | 登録日 | 2002-05-15 | 公開日 | 2002-11-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Function of His185 in Aquifex aeolicus 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase J.Mol.Biol., 324, 2002
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