6Z1G
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![BU of 6z1g by Molmil](/molmil-images/mine/6z1g) | CryoEM structure of the interaction between Rubisco Activase small-subunit-like (SSUL) domain with Rubisco from Nostoc sp. (strain PCC7120) | Descriptor: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain, Ribulose bisphosphate carboxylase/oxygenase activase | Authors: | Wang, H, Bracher, A, Flecken, M, Popilka, L, Hartl, F.U, Hayer-Hartl, M. | Deposit date: | 2020-05-13 | Release date: | 2020-09-23 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes. Cell, 183, 2020
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1VFJ
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![BU of 1vfj by Molmil](/molmil-images/mine/1vfj) | Crystal structure of TT1020 from Thermus thermophilus HB8 | Descriptor: | nitrogen regulatory protein p-II | Authors: | Wang, H, Sakai, H, Takemoto-Hori, C, Kaminishi, T, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-04-15 | Release date: | 2005-01-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of the signal transducing protein GlnK from Thermus thermophilus HB8 J.STRUCT.BIOL., 149, 2005
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5VJ6
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![BU of 5vj6 by Molmil](/molmil-images/mine/5vj6) | |
5W2I
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![BU of 5w2i by Molmil](/molmil-images/mine/5w2i) | Crystal structure of the core catalytic domain of human inositol phosphate multikinase soaked with C4-analogue of PtdIns(4,5)P2 and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase, ... | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2017-06-06 | Release date: | 2017-09-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural features of human inositol phosphate multikinase rationalize its inositol phosphate kinase and phosphoinositide 3-kinase activities. J. Biol. Chem., 292, 2017
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3HBT
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![BU of 3hbt by Molmil](/molmil-images/mine/3hbt) | The structure of native G-actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ... | Authors: | Wang, H, Robinson, R.C, Burtnick, L.D. | Deposit date: | 2009-05-05 | Release date: | 2010-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of native G-actin Cytoskeleton (Hoboken), 67, 2010
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3USG
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![BU of 3usg by Molmil](/molmil-images/mine/3usg) | Crystal structure of LeuT bound to L-leucine in space group C2 from lipid bicelles | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, LEUCINE, ... | Authors: | Wang, H, Elferich, J, Gouaux, E. | Deposit date: | 2011-11-23 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
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3USJ
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![BU of 3usj by Molmil](/molmil-images/mine/3usj) | |
3USK
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3USL
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![BU of 3usl by Molmil](/molmil-images/mine/3usl) | Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles | Descriptor: | ACETATE ION, IODIDE ION, PHOSPHOCHOLINE, ... | Authors: | Wang, H, Elferich, J, Gouaux, E. | Deposit date: | 2011-11-23 | Release date: | 2012-01-11 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
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4O4B
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4NZN
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![BU of 4nzn by Molmil](/molmil-images/mine/4nzn) | Crystal structure of the catalytic domain of PPIP5K2 in complex with AMPPNP and 2-O-BN-5-PA-INSP4 | Descriptor: | (2-{[(1s,2R,3R,4r,5S,6S)-4-(benzyloxy)-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl]oxy}-2-oxoethyl)phosphonic acid, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, MAGNESIUM ION, ... | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2013-12-12 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery. Chem.Biol., 21, 2014
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4O4E
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![BU of 4o4e by Molmil](/molmil-images/mine/4o4e) | Crystal Structure of an Inositol hexakisphosphate kinase EhIP6KA in complexed with ATP and Ins(1,3,4,5,6)P5 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Inositol hexakisphosphate kinase, MAGNESIUM ION, ... | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2013-12-18 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | IP6K structure and the molecular determinants of catalytic specificity in an inositol phosphate kinase family. Nat Commun, 5, 2014
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5DGI
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![BU of 5dgi by Molmil](/molmil-images/mine/5dgi) | Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and 3,5-(PCP)2-IP4 | Descriptor: | 1,2-ETHANEDIOL, 3,5-di-methylenebisphosphonate inositol tetrakisphosphate, ACETATE ION, ... | Authors: | Wang, H, Shears, S.B. | Deposit date: | 2015-08-27 | Release date: | 2016-08-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues. Chemistry, 22, 2016
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8BZN
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![BU of 8bzn by Molmil](/molmil-images/mine/8bzn) | SARS-CoV-2 non-structural protein 10 (nsp10) variant T102I | Descriptor: | CHLORIDE ION, DIMETHYL SULFOXIDE, Replicase polyprotein 1ab, ... | Authors: | Wang, H, Rizvi, S.R.A, Dong, D, Lou, J, Wang, Q, Sopipong, W, Najar, F, Agarwal, P.K, Kozielski, F, Haider, S. | Deposit date: | 2022-12-15 | Release date: | 2023-12-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16. Elife, 12, 2023
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6T9J
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![BU of 6t9j by Molmil](/molmil-images/mine/6t9j) | SAGA Tra1 module | Descriptor: | Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1 | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T9I
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![BU of 6t9i by Molmil](/molmil-images/mine/6t9i) | cryo-EM structure of transcription coactivator SAGA | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T9K
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![BU of 6t9k by Molmil](/molmil-images/mine/6t9k) | SAGA Core module | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T9L
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7XYD
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![BU of 7xyd by Molmil](/molmil-images/mine/7xyd) | Crystal structure of TMPRSS2 in complex with Nafamostat | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | Authors: | Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H. | Deposit date: | 2022-06-01 | Release date: | 2023-12-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
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7Y0F
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![BU of 7y0f by Molmil](/molmil-images/mine/7y0f) | Crystal structure of TMPRSS2 in complex with UK-371804 | Descriptor: | 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H. | Deposit date: | 2022-06-04 | Release date: | 2023-12-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
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7Y0E
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![BU of 7y0e by Molmil](/molmil-images/mine/7y0e) | Crystal structure of TMPRSS2 in complex with Camostat | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | Authors: | Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H. | Deposit date: | 2022-06-04 | Release date: | 2023-12-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
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6S01
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![BU of 6s01 by Molmil](/molmil-images/mine/6s01) | Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Wang, H, Farnung, L, Dienemann, C, Cramer, P. | Deposit date: | 2019-06-13 | Release date: | 2019-12-18 | Last modified: | 2020-01-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nat.Struct.Mol.Biol., 27, 2020
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8EAV
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![BU of 8eav by Molmil](/molmil-images/mine/8eav) | YAR027W and YAR028W in complex with c subunits from yeast VO complex | Descriptor: | YAR027W or YAR028W, subunit from the c ring of yeast VO complex | Authors: | Wang, H, Bueler, S.A, Rubinstein, J.L. | Deposit date: | 2022-08-29 | Release date: | 2022-11-02 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EAT
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![BU of 8eat by Molmil](/molmil-images/mine/8eat) | Yeast VO missing subunits a, e, and f in complex with Vma12-22p | Descriptor: | V-type proton ATPase subunit F, V-type proton ATPase subunit c, V-type proton ATPase subunit c', ... | Authors: | Wang, H, Bueler, S.A, Rubinstein, J.L. | Deposit date: | 2022-08-29 | Release date: | 2022-11-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EAS
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![BU of 8eas by Molmil](/molmil-images/mine/8eas) | Yeast VO in complex with Vma12-22p | Descriptor: | V-type proton ATPase assembly factor Vma12p, V-type proton ATPase subunit F, V-type proton ATPase subunit a, ... | Authors: | Wang, H, Bueler, S.A, Rubinstein, J.L. | Deposit date: | 2022-08-29 | Release date: | 2022-11-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p. Proc.Natl.Acad.Sci.USA, 120, 2023
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