1U9U
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![BU of 1u9u by Molmil](/molmil-images/mine/1u9u) | Crystal structure of F58Y mutant of cytochrome b5 | Descriptor: | Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Shan, L, Lu, J.-X, Gan, J.-H, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X. | Deposit date: | 2004-08-11 | Release date: | 2005-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure of the F58W mutant of cytochrome b5: the mutation leads to multiple conformations and weakens stacking interactions. Acta Crystallogr.,Sect.D, 61, 2005
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2P4Q
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![BU of 2p4q by Molmil](/molmil-images/mine/2p4q) | Crystal Structure Analysis of Gnd1 in Saccharomyces cerevisiae | Descriptor: | 6-phosphogluconate dehydrogenase, decarboxylating 1, CITRATE ANION | Authors: | He, W, Wang, Y, Liu, W, Zhou, C.Z. | Deposit date: | 2007-03-12 | Release date: | 2007-07-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1 Bmc Struct.Biol., 7, 2007
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2DD4
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![BU of 2dd4 by Molmil](/molmil-images/mine/2dd4) | Thiocyanate hydrolase (SCNase) from Thiobacillus thioparus recombinant apo-enzyme | Descriptor: | L(+)-TARTARIC ACID, Thiocyanate hydrolase alpha subunit, Thiocyanate hydrolase beta subunit, ... | Authors: | Arakawa, T, Kawano, Y, Kataoka, S, Katayama, Y, Kamiya, N, Yohda, M, Odaka, M. | Deposit date: | 2006-01-19 | Release date: | 2007-01-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structure of thiocyanate hydrolase: a new nitrile hydratase family protein with a novel five-coordinate cobalt(III) center. J.Mol.Biol., 366, 2007
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2DD5
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![BU of 2dd5 by Molmil](/molmil-images/mine/2dd5) | Thiocyanate hydrolase (SCNase) from Thiobacillus thioparus native holo-enzyme | Descriptor: | COBALT (III) ION, SULFATE ION, Thiocyanate hydrolase alpha subunit, ... | Authors: | Arakawa, T, Kawano, Y, Kataoka, S, Katayama, Y, Kamiya, N, Yohda, M, Odaka, M. | Deposit date: | 2006-01-19 | Release date: | 2007-01-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of thiocyanate hydrolase: a new nitrile hydratase family protein with a novel five-coordinate cobalt(III) center. J.Mol.Biol., 366, 2007
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6LY6
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![BU of 6ly6 by Molmil](/molmil-images/mine/6ly6) | PylRS C-terminus domain mutant bound with 3-(1-Naphthyl)-L-alanine and AMPNP | Descriptor: | MAGNESIUM ION, NAPHTHALEN-2-YL-3-ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Weng, J.H, Tsai, M.D, Wang, Y.S. | Deposit date: | 2020-02-13 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5001328 Å) | Cite: | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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2DXB
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![BU of 2dxb by Molmil](/molmil-images/mine/2dxb) | Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers | Descriptor: | COBALT (III) ION, PHOSPHATE ION, Thiocyanate hydrolase subunit alpha, ... | Authors: | Arakawa, T, Kawano, Y, Katayama, Y, Yohda, M, Odaka, M. | Deposit date: | 2006-08-25 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification J.Am.Chem.Soc., 131, 2009
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6LY3
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![BU of 6ly3 by Molmil](/molmil-images/mine/6ly3) | PylRS C-terminus domain mutant bound with 3-Benzothienyl-L-alanine and AMPNP | Descriptor: | 3-(1-benzothiophen-3-yl)-L-alanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Weng, J.H, Tsai, M.D, Wang, Y.S. | Deposit date: | 2020-02-13 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.89590144 Å) | Cite: | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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7DDC
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![BU of 7ddc by Molmil](/molmil-images/mine/7ddc) | Crystal structure of SARS-CoV-2 main protease in complex with Tafenoquine | Descriptor: | 3C-like proteinase, Tafenoquine | Authors: | Chen, Y, Wang, Y.C, Yang, C.S, Hung, M.C. | Deposit date: | 2020-10-28 | Release date: | 2021-11-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.175 Å) | Cite: | Tafenoquine and its derivatives as inhibitors for the severe acute respiratory syndrome coronavirus 2. J.Biol.Chem., 298, 2022
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7CZ5
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![BU of 7cz5 by Molmil](/molmil-images/mine/7cz5) | Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex | Descriptor: | CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2020-09-07 | Release date: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for activation of the growth hormone-releasing hormone receptor. Nat Commun, 11, 2020
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4WHG
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![BU of 4whg by Molmil](/molmil-images/mine/4whg) | Crystal Structure of TR3 LBD in complex with Molecule 3 | Descriptor: | 1-(3,4,5-trihydroxyphenyl)octan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 | Authors: | Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Wang, Y, Hou, P.P, Wu, Q, Lin, T.W. | Deposit date: | 2014-09-22 | Release date: | 2015-09-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22, 2015
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6LTU
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![BU of 6ltu by Molmil](/molmil-images/mine/6ltu) | Crystal structure of Cas12i2 ternary complex with double Mg2+ bound in catalytic pocket | Descriptor: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-23 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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4WHF
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![BU of 4whf by Molmil](/molmil-images/mine/4whf) | Crystal Structure of TR3 LBD in complex with 1-(3,4,5-trihydroxyphenyl)decan-1-one | Descriptor: | 1-(3,4,5-trihydroxyphenyl)decan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 | Authors: | Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Wang, Y, Hou, P.P, Wu, Q, Lin, T.W. | Deposit date: | 2014-09-22 | Release date: | 2015-09-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22, 2015
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7DHJ
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![BU of 7dhj by Molmil](/molmil-images/mine/7dhj) | The co-crystal structure of SARS-CoV-2 main protease with the peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)pent-4-ynamide | Descriptor: | (2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pent-4-ynamide, 3C-like proteinase | Authors: | Shang, L.Q, Wang, H, Deng, W.L, Xing, S, Wang, Y.X. | Deposit date: | 2020-11-15 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.962 Å) | Cite: | The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022
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5X3P
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5X4L
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![BU of 5x4l by Molmil](/molmil-images/mine/5x4l) | Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain | Descriptor: | Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7 | Authors: | Jiang, T, Li, Z, Wang, Y, Xu, M. | Deposit date: | 2017-02-13 | Release date: | 2017-03-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase Biochem. Biophys. Res. Commun., 486, 2017
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2P01
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![BU of 2p01 by Molmil](/molmil-images/mine/2p01) | The structure of receptor-associated protein(RAP) | Descriptor: | Alpha-2-macroglobulin receptor-associated protein | Authors: | Lee, D, Walsh, J.D, Migliorini, M, Yu, P, Cai, T, Schwieters, C.D, Krueger, S, Strickland, D.K, Wang, Y.X. | Deposit date: | 2007-02-28 | Release date: | 2007-08-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of receptor-associated protein (RAP). Protein Sci., 16, 2007
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6E6S
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![BU of 6e6s by Molmil](/molmil-images/mine/6e6s) | 1.45 A resolution structure of the C-terminally truncated [2Fe-2S] ferredoxin (Bfd) R26E/K46Y mutant from Pseudomonas aeruginosa | Descriptor: | Bacterioferritin-associated ferredoxin, FE2/S2 (INORGANIC) CLUSTER | Authors: | Lovell, S, Wijerathne, H, Battaile, K.P, Yao, H, Wang, Y, Rivera, M. | Deposit date: | 2018-07-25 | Release date: | 2018-09-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site. Biochemistry, 57, 2018
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2P03
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![BU of 2p03 by Molmil](/molmil-images/mine/2p03) | The structure of receptor-associated protein(RAP) | Descriptor: | Alpha-2-macroglobulin receptor-associated protein | Authors: | Lee, D, Walsh, J.D, Migliorini, M, Yu, P, Cai, T, Schwieters, C.D, Krueger, S, Strickland, D.K, Wang, Y.X. | Deposit date: | 2007-02-28 | Release date: | 2007-08-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of receptor-associated protein (RAP). Protein Sci., 16, 2007
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5B0H
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![BU of 5b0h by Molmil](/molmil-images/mine/5b0h) | CRYSTAL STRUCTURE OF HUMAN LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 | Descriptor: | Leukocyte cell-derived chemotaxin-2, SULFATE ION, ZINC ION | Authors: | Zheng, H, Miyakawa, T, Sawano, Y, Tanokura, M. | Deposit date: | 2015-10-29 | Release date: | 2016-07-06 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal Structure of Human Leukocyte Cell-derived Chemotaxin 2 (LECT2) Reveals a Mechanistic Basis of Functional Evolution in a Mammalian Protein with an M23 Metalloendopeptidase Fold J.Biol.Chem., 291, 2016
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6E6Q
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![BU of 6e6q by Molmil](/molmil-images/mine/6e6q) | 1.20 A resolution structure of the C-terminally truncated [2Fe-2S] ferredoxin (Bfd) from Pseudomonas aeruginosa | Descriptor: | Bacterioferritin-associated ferredoxin, FE2/S2 (INORGANIC) CLUSTER | Authors: | Lovell, S, Wijerathne, H, Battaile, K.P, Yao, H, Wang, Y, Rivera, M. | Deposit date: | 2018-07-25 | Release date: | 2018-09-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Bfd, a New Class of [2Fe-2S] Protein That Functions in Bacterial Iron Homeostasis, Requires a Structural Anion Binding Site. Biochemistry, 57, 2018
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2EJX
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![BU of 2ejx by Molmil](/molmil-images/mine/2ejx) | Crystal structure of the hypothetical protein STK_08120 from Sulfolobus tokodaii | Descriptor: | STK_08120 | Authors: | Miyakawa, T, Miyazono, K, Sawano, Y, Hatano, K, Nagata, K, Tanokura, M. | Deposit date: | 2007-03-21 | Release date: | 2008-03-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | A thermoacidophile-specific protein family, DUF3211, functions as a fatty acid carrier with novel binding mode J.Bacteriol., 195, 2013
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6I59
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![BU of 6i59 by Molmil](/molmil-images/mine/6i59) | Long wavelength native-SAD phasing of Sen1 helicase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M. | Deposit date: | 2018-11-13 | Release date: | 2019-03-13 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Long-wavelength native-SAD phasing: opportunities and challenges. Iucrj, 6, 2019
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3ZIF
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![BU of 3zif by Molmil](/molmil-images/mine/3zif) | Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly | Descriptor: | HEXON PROTEIN, PENTON PROTEIN, PIX, ... | Authors: | Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P. | Deposit date: | 2013-01-09 | Release date: | 2014-01-22 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates Virology, 450, 2014
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7D4U
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![BU of 7d4u by Molmil](/molmil-images/mine/7d4u) | ATP complex with double mutant cyclic trinucleotide synthase CdnD | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase | Authors: | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | Deposit date: | 2020-09-24 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
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7D4S
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![BU of 7d4s by Molmil](/molmil-images/mine/7d4s) | apo-form cyclic trinucleotide synthase CdnD | Descriptor: | Cyclic AMP-AMP-GMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION | Authors: | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | Deposit date: | 2020-09-24 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
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