1J9C
 
 | | Crystal Structure of tissue factor-factor VIIa complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-phenylalaninamide, ... | | 著者 | Huang, M, Ruf, W, Edgington, T.S, Wilson, I.A. | | 登録日 | 2001-05-24 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Ligand Induced Conformational Transitions of Tissue Factor. Crystal Structure of the Tissue Factor:Factor VIIa Complex.
To be Published
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1JGV
 | | STRUCTURAL BASIS FOR DISFAVORED ELIMINATION REACTION IN CATALYTIC ANTIBODY 1D4 | | 分子名称: | Antibody Heavy Chain, Antibody Light Chain | | 著者 | Larsen, N.A, Heine, A, Crane, L, Cravatt, B.F, Lerner, R.A, Wilson, I.A. | | 登録日 | 2001-06-26 | | 公開日 | 2001-12-05 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for a disfavored elimination reaction in catalytic antibody 1D4.
J.Mol.Biol., 314, 2001
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1C5B
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1C5C
 | | DECARBOXYLASE CATALYTIC ANTIBODY 21D8-HAPTEN COMPLEX | | 分子名称: | 2-ACETYLAMINO-NAPTHALENE-1,5-DISULFONIC ACID, CHIMERIC DECARBOXYLASE ANTIBODY 21D8, GLYCEROL | | 著者 | Hotta, K, Wilson, I.A. | | 登録日 | 1999-11-09 | | 公開日 | 2000-10-11 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.
J.Mol.Biol., 302, 2000
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1JKX
 | | Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase | | 分子名称: | N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | | 著者 | Greasley, S.E, Marsilje, T.H, Cai, H, Baker, S, Benkovic, S.J, Boger, D.L, Wilson, I.A. | | 登録日 | 2001-07-13 | | 公開日 | 2001-11-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase.
Biochemistry, 40, 2001
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1I9E
 | | TCR DOMAIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOTOXIC TCELL VALPHA DOMAIN | | 著者 | Rudolph, M.G, Huang, M, Teyton, L, Wilson, I.A. | | 登録日 | 2001-03-19 | | 公開日 | 2001-12-05 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.
J.Mol.Biol., 314, 2001
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1JU3
 | | BACTERIAL COCAINE ESTERASE COMPLEX WITH TRANSITION STATE ANALOG | | 分子名称: | PHENYL BORONIC ACID, cocaine esterase | | 著者 | Larsen, N.A, Turner, J.M, Stevens, J, Rosser, S.J, Basran, A, Lerner, R.A, Bruce, N.C, Wilson, I.A. | | 登録日 | 2001-08-23 | | 公開日 | 2001-12-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal structure of a bacterial cocaine esterase.
Nat.Struct.Biol., 9, 2002
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1CD1
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1D5T
 | | GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM | | 分子名称: | GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, SULFATE ION | | 著者 | Peng, L, Zeng, K, Heine, A, Moyer, B, Greasley, S.E, Kuhn, P, Balch, W.E, Wilson, I.A. | | 登録日 | 1999-10-11 | | 公開日 | 2000-10-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling.
Traffic, 1, 2000
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1JCL
 | | OBSERVATION OF COVALENT INTERMEDIATES IN AN ENZYME MECHANISM AT ATOMIC RESOLUTION | | 分子名称: | 1-HYDROXY-PENTANE-3,4-DIOL-5-PHOSPHATE, DEOXYRIBOSE-PHOSPHATE ALDOLASE | | 著者 | Heine, A, DeSantis, G, Luz, J.G, Mitchell, M, Wong, C.-H, Wilson, I.A. | | 登録日 | 2001-06-09 | | 公開日 | 2001-10-31 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Observation of covalent intermediates in an enzyme mechanism at atomic resolution.
Science, 294, 2001
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1JU4
 | | BACTERIAL COCAINE ESTERASE COMPLEX WITH PRODUCT | | 分子名称: | BENZOIC ACID, cocaine esterase | | 著者 | Larsen, N.A, Turner, J.M, Stevens, J, Rosser, S.J, Basran, A, Lerner, R.A, Bruce, N.C, Wilson, I.A. | | 登録日 | 2001-08-23 | | 公開日 | 2001-12-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Crystal structure of a bacterial cocaine esterase.
Nat.Struct.Biol., 9, 2002
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1ES0
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1ED3
 | | CRYSTAL STRUCTURE OF RAT MINOR HISTOCOMPATIBILITY ANTIGEN COMPLEX RT1-AA/MTF-E. | | 分子名称: | BETA-2-MICROGLOBULIN, CLASS I MAJOR HISTOCOMPATIBILITY ANTIGEN RT1-AA, PEPTIDE MTF-E (13N3E) | | 著者 | Speir, J.A, Stevens, J, Joly, E, Butcher, G.W, Wilson, I.A. | | 登録日 | 2000-01-26 | | 公開日 | 2001-02-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa.
Immunity, 14, 2001
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1KBG
 | | MHC Class I H-2KB Presented Glycopeptide RGY8-6H-GAL2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (BETA-2-MICROGLOBULIN), ... | | 著者 | Speir, J.A, Abdel-Motal, U.M, Jondal, M, Wilson, I.A. | | 登録日 | 1998-08-28 | | 公開日 | 1999-02-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL.
Immunity, 10, 1999
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1JGU
 | | STRUCTURAL BASIS FOR DISFAVORED ELIMINATION REACTION IN CATALYTIC ANTIBODY 1D4 | | 分子名称: | (2-AMINO-3-PHENYL-BICYCLO[2.2.1]HEPT-2-YL)-PHENYL-METHANONE, Antibody Heavy Chain, Antibody Light Chain, ... | | 著者 | Larsen, N.A, Heine, A, Crane, L, Cravatt, B.F, Lerner, R.A, Wilson, I.A. | | 登録日 | 2001-06-26 | | 公開日 | 2001-12-05 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for a disfavored elimination reaction in catalytic antibody 1D4.
J.Mol.Biol., 314, 2001
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1I7Z
 | | ANTIBODY GNC92H2 BOUND TO LIGAND | | 分子名称: | CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION, COCAINE | | 著者 | Larsen, N.A, Wilson, I.A. | | 登録日 | 2001-03-12 | | 公開日 | 2001-08-08 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of a cocaine-binding antibody.
J.Mol.Biol., 311, 2001
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1C16
 | | CRYSTAL STRUCTURE ANALYSIS OF THE GAMMA/DELTA T CELL LIGAND T22 | | 分子名称: | MHC-LIKE PROTEIN T22, PROTEIN (BETA-2-MICROGLOBULIN) | | 著者 | Wingren, C, Crowley, M.P, Degano, M, Chien, Y, Wilson, I.A. | | 登録日 | 1999-07-20 | | 公開日 | 2000-01-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of a gammadelta T cell receptor ligand T22: a truncated MHC-like fold.
Science, 287, 2000
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1HQ8
 | | CRYSTAL STRUCTURE OF THE MURINE NK CELL-ACTIVATING RECEPTOR NKG2D AT 1.95 A | | 分子名称: | NKG2-D | | 著者 | Wolan, D.W, Teyton, L, Rudolph, M.G, Villmow, B, Bauer, S, Busch, D.H, Wilson, I.A. | | 登録日 | 2000-12-14 | | 公開日 | 2001-03-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A.
Nat.Immunol., 2, 2001
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1L2H
 | | Crystal structure of Interleukin 1-beta F42W/W120F mutant | | 分子名称: | Interleukin 1-beta | | 著者 | Rudolph, M.G, Kelker, M.S, Schneider, T.R, Yeates, T.O, Oseroff, V, Heidary, D.K, Jennings, P.A, Wilson, I.A. | | 登録日 | 2002-02-21 | | 公開日 | 2003-02-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.
Acta Crystallogr.,Sect.D, 59, 2003
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1EBP
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1FGN
 | | MONOCLONAL MURINE ANTIBODY 5G9-ANTI-HUMAN TISSUE FACTOR | | 分子名称: | IMMUNOGLOBULIN FAB 5G9 | | 著者 | Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A. | | 登録日 | 1997-04-10 | | 公開日 | 1998-02-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.5G9 complex.
J.Mol.Biol., 275, 1998
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1FIG
 | | ROUTES TO CATALYSIS: STRUCTURE OF A CATALYTIC ANTIBODY AND COMPARISON WITH ITS NATURAL COUNTERPART | | 分子名称: | 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, IGG1-KAPPA 1F7 FAB (HEAVY CHAIN), IGG1-KAPPA 1F7 FAB (LIGHT CHAIN) | | 著者 | Haynes, M.R, Stura, E.A, Hilvert, D, Wilson, I.A. | | 登録日 | 1994-01-07 | | 公開日 | 1994-05-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart.
Science, 263, 1994
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1F6B
 | | CRYSTAL STRUCTURE OF SAR1-GDP COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SAR1, ... | | 著者 | Huang, M, Wilson, I.A, Balch, W.E. | | 登録日 | 2000-06-21 | | 公開日 | 2002-01-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of Sar1-GDP at 1.7 A resolution and the role of the NH2 terminus in ER export.
J.Cell Biol., 155, 2001
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1LK2
 | | 1.35A crystal structure of H-2Kb complexed with the GNYSFYAL peptide | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Luz, J.G, Rudolph, M.G, Wilson, I.A, Eisen, H. | | 登録日 | 2002-04-23 | | 公開日 | 2003-11-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects.
J.Immunol., 172, 2004
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1FZM
 | | MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A. | | 登録日 | 2000-10-03 | | 公開日 | 2001-03-28 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
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