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PDB: 901 件

7JMO
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Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-04
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-04 heavy chain, COVA2-04 light chain, ...
著者Wu, N.C, Yuan, M, Liu, H, Zhu, X, Wilson, I.A.
登録日2020-08-02
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.359 Å)
主引用文献An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain.
Cell Rep, 33, 2020
3O2W
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Crystal structure of the 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe Fab in complex with a 39A11 transition state analog
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, Chimeric antibody Fab 1E9, ...
著者Verdino, P, Wilson, I.A.
登録日2010-07-22
公開日2011-07-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe Fab in complex with a 39A11 transition state analog
To be Published
3OB0
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A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity
分子名称: 7-deoxy-L-glycero-alpha-D-manno-heptopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, Fab 2G12, heavy chain, ...
著者Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G.
登録日2010-08-06
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3QQB
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Crystal structure of HA2 R106H mutant of H2 hemagglutinin, neutral pH form
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xu, R, Wilson, I.A.
登録日2011-02-15
公開日2011-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin.
J.Virol., 85, 2011
3RG1
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Crystal structure of the RP105/MD-1 complex
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CD180 molecule, LY86 protein, ...
著者Yoon, S.I, Hong, M, Wilson, I.A.
登録日2011-04-07
公開日2011-08-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1.
Nat.Struct.Mol.Biol., 18, 2011
3QL3
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Re-refined coordinates for PDB entry 1RX2
分子名称: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ...
著者Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
登録日2011-02-02
公開日2011-04-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
3QG6
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Structural Basis for Ligand Recognition and Discrimination of a Quorum Quenching Antibody
分子名称: AP4-24H11 Heavy Chain, AP4-24H11 Light Chain, Agr autoinducing peptide, ...
著者Kirchdoerfer, R.N, Janda, J.D, Kaufmann, G.F, Wilson, I.A.
登録日2011-01-24
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
3R06
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Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment
分子名称: anti-mouse CD3epsilon antibody 2C11 Fab heavy chain, anti-mouse CD3epsilon antibody 2C11 Fab light chain
著者Shore, D.A, Zhu, X, Wilson, I.A.
登録日2011-03-07
公開日2012-01-25
最終更新日2013-09-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
J.Biol.Chem., 287, 2012
7KN3
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BU of 7kn3 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, S-B8 Fab heavy chain, ...
著者Liu, H, Zhu, X, Wilson, I.A.
登録日2020-11-04
公開日2021-09-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
7KN4
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Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-E6 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S-E6 Fab heavy chain, S-E6 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2020-11-04
公開日2021-09-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
3Q1S
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HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ...
著者Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A.
登録日2010-12-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope.
J.Mol.Biol., 414, 2011
3QG7
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Structural Basis for Ligand Recognition and Discrimination of a Quorum Quenching Antibody
分子名称: AP4-24H11 Antibody Heavy Chain, AP4-24H11 Antibody Light Chain, HEXAETHYLENE GLYCOL, ...
著者Kirchdoerfer, R.K, Kaufmann, G.F, Janda, J.D, Wilson, I.A.
登録日2011-01-24
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
7KKZ
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BU of 7kkz by Molmil
Crystal structure of mouse anti-HIV potent neutralizing antibody M4H2K1
分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Heavy chain of Fab fragment of mouse monoclonal antibody M4H2K1, ...
著者Kumar, S, Wilson, I.A.
登録日2020-10-28
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KMD
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BU of 7kmd by Molmil
Crystal structure of a HIV-1 clade C isolate Du172.17 HR1.R4.664 Env trimer in complex with human Fabs PGT124 and 35O22
分子名称: 124 Heavy chain, 124 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kumar, S, Wilson, I.A.
登録日2020-11-02
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.39228582 Å)
主引用文献Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KLC
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BU of 7klc by Molmil
Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab
分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kumar, S, Wilson, I.A.
登録日2020-10-29
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
3QHF
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BU of 3qhf by Molmil
Crystal Structure of Fab del2D1, a deletion variant of anti-influenza antibody 2D1
分子名称: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
著者Ekiert, D.C, Wilson, I.A.
登録日2011-01-25
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.655 Å)
主引用文献An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3QHZ
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Crystal Structure of human anti-influenza Fab 2D1
分子名称: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
著者Ekiert, D.C, Wilson, I.A.
登録日2011-01-26
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
7KN6
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BU of 7kn6 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
著者Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
登録日2020-11-04
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
7KN7
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BU of 7kn7 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH W and antibody Fab CC12.3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ...
著者Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
登録日2020-11-04
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.
Science, 371, 2021
3R08
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BU of 3r08 by Molmil
Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab
分子名称: Mouse anti-mouse CD3epsilon antibody 2C11 heavy chain, Mouse anti-mouse CD3epsilon antibody 2C11 light chain, T-cell surface glycoprotein CD3 epsilon chain
著者Shore, D.A, Zhu, X, Wilson, I.A.
登録日2011-03-07
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
J.Biol.Chem., 287, 2012
3R2X
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BU of 3r2x by Molmil
Crystal structure of the de novo designed binding protein HB36.3 in complex the the 1918 influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HB36.3, designed hemagglutinin binding protein, ...
著者Ekiert, D.C, Wilson, I.A.
登録日2011-03-14
公開日2011-05-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.
Science, 332, 2011
7LOP
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BU of 7lop by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV05-163 and CR3022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 Fab heavy chain, CR3022 Fab light chain, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2021-02-10
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.246 Å)
主引用文献Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.
Science, 373, 2021
3QL0
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BU of 3ql0 by Molmil
Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
登録日2011-02-02
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
3QQE
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BU of 3qqe by Molmil
Crystal structure of HA2 R106H mutant of H2 hemagglutinin, re-neutralized form
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xu, R, Wilson, I.A.
登録日2011-02-15
公開日2011-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin.
J.Virol., 85, 2011
3QQI
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Crystal structure of the HA1 receptor binding domain of H2 hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemagglutinin
著者Xu, R, Wilson, I.A.
登録日2011-02-15
公開日2011-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin.
J.Virol., 85, 2011

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