7F5D
 
 | | Crystal structure of BPTF-BRD with ligand DC-BPi-03 bound | | 分子名称: | 6-(1H-indol-5-yl)-N-methyl-2-methylsulfonyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | | 登録日 | 2021-06-21 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.57150865 Å) | | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins
To Be Published
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7F5E
 | | Crystal structure of BPTF-BRD with ligand DC-BPi-11 bound | | 分子名称: | N,N-dimethyl-3-[5-(2-methylsulfonyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)indol-1-yl]propan-1-amine, Nucleosome-remodeling factor subunit BPTF | | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | | 登録日 | 2021-06-21 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.20017123 Å) | | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins
To Be Published
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7F5C
 | | Crystal structure of BPTF-BRD with ligand DC-BPi-07 bound | | 分子名称: | 6-[1-[3-(dimethylamino)propyl]indol-5-yl]-2-methylsulfonyl-N-propyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | | 登録日 | 2021-06-21 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65004492 Å) | | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins
To Be Published
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3S7X
 | | Unassembled Washington University Polyomavirus VP1 Pentamer R198K Mutant | | 分子名称: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1, ... | | 著者 | Neu, U, Wang, J, Stehle, T. | | 登録日 | 2011-05-27 | | 公開日 | 2011-06-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the major capsid proteins of the human KI and WU polyomaviruses.
J.Virol., 85, 2011
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3RWU
 | | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Difluorotoluene Nucleoside | | 分子名称: | 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*GP*(DFT)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Xia, S, Konigsberg, W.H, Wang, J. | | 登録日 | 2011-05-09 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Hydrogen-Bonding Capability of a Templating Difluorotoluene Nucleotide Residue in an RB69 DNA Polymerase Ternary Complex.
J.Am.Chem.Soc., 133, 2011
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3S0Z
 | | Crystal structure of New Delhi Metallo-beta-lactamase (NDM-1) | | 分子名称: | Metallo-beta-lactamase, ZINC ION | | 著者 | Guo, Y, Wang, J, Niu, G.J, Shui, W.Q, Sun, Y.N, Lou, Z.Y, Rao, Z.H. | | 登録日 | 2011-05-13 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A structural view of the antibiotic degradation enzyme NDM-1 from a superbug.
Protein Cell, 2011
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3QEW
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3QES
 | | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dGTP Opposite Difluorotoluene Nucleoside | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | | 著者 | Xia, S, Konigsberg, W.H, Wang, J. | | 登録日 | 2011-01-20 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue.
Biochemistry, 51, 2012
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3QET
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3SIP
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3RZC
 | | Structure of the self-antigen iGb3 bound to mouse CD1d and in complex with the iNKT TCR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ... | | 著者 | Yu, E.D, Girardi, E, Wang, J, Zajonc, D.M. | | 登録日 | 2011-05-11 | | 公開日 | 2011-08-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Cutting Edge: Structural Basis for the Recognition of {beta}-Linked Glycolipid Antigens by Invariant NKT Cells.
J.Immunol., 187, 2011
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3RC8
 | | Human Mitochondrial Helicase Suv3 in Complex with Short RNA Fragment | | 分子名称: | ATP-dependent RNA helicase SUPV3L1, mitochondrial, RNA fragment | | 著者 | Dauter, Z, Jedrzejczak, R, Dauter, M, Wang, J, Szczesny, R, Stepien, P. | | 登録日 | 2011-03-30 | | 公開日 | 2011-05-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Human Suv3 protein reveals unique features among SF2 helicases.
Acta Crystallogr.,Sect.D, 67, 2011
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2KQT
 | | Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine | | 分子名称: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, M2 protein | | 著者 | Cady, S.D, Schmidt-Rohr, K, Wang, J, Soto, C.S, DeGrado, W.F, Hong, M. | | 登録日 | 2009-11-18 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
Nature, 463, 2010
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2PZY
 | | Structure of MK2 Complexed with Compound 76 | | 分子名称: | (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE, MAP kinase-activated protein kinase 2, STAUROSPORINE | | 著者 | White, A, Wu, J.P, Wang, J, Abeywardane, A, Andersen, D, Emmanuel, M, Gautschi, E, Goldberg, D.R, Kashem, M.A, Lukas, S, Mao, W, Martin, L, Morwick, T, Moss, N, Pargellis, C, Patel, U.R, Patnaude, L, Peet, G.W, Skow, D, Snow, R.J, Ward, Y, Werneburg, B. | | 登録日 | 2007-05-18 | | 公開日 | 2007-07-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The discovery of carboline analogs as potent MAPKAP-K2 inhibitors
Bioorg.Med.Chem.Lett., 17, 2007
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3UJ3
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3UIQ
 | | RB69 DNA Polymerase Ternary Complex containing dUpNpp | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*GP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ... | | 著者 | Xia, S, Konigsberg, W.H, Wang, J. | | 登録日 | 2011-11-05 | | 公開日 | 2012-04-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.879 Å) | | 主引用文献 | Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase.
Protein Sci., 21, 2012
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7DZE
 | | Fabp ground state captured by XFELs | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZH
 | | intermediate of FABP with a delay time of 100 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZF
 | | Intermediate of FABP with a delay time of 10 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZG
 | | Intermediate of FABP with a delay time of 30 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZI
 | | intermediate of FABP with a delay time of 300 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZJ
 | | Fabp protein before hv | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZK
 | | Fabp protein after hv | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZL
 | | A69C-M71L mutant of Fabp protein | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7Y62
 | | Crystal structure of human TFEB HLHLZ domain | | 分子名称: | Transcription factor EB | | 著者 | Yang, G, Li, P, Lin, Y, Liu, Z, Sun, H, Zhao, Z, Fang, P, Wang, J. | | 登録日 | 2022-06-18 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Proc.Natl.Acad.Sci.USA, 120, 2023
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