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PDB: 12895 results

4AFQ
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BU of 4afq by Molmil
Human Chymase - Fynomer Complex
Descriptor: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHYMASE, CITRATE ANION, ...
Authors:Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M.
Deposit date:2012-01-23
Release date:2012-07-11
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain.
Mabs, 4, 2012
8AKE
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BU of 8ake by Molmil
Human Sirt6 in complex with ADP-ribose and fragment nicotinamide
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
3K3T
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BU of 3k3t by Molmil
E185A mutant of peptidoglycan hydrolase from Sphingomonas sp. A1
Descriptor: Peptidoglycan hydrolase FlgJ, SULFATE ION
Authors:Maruyama, Y, Ochiai, A, Itoh, T, Mikami, B, Hashimoto, W, Murata, K.
Deposit date:2009-10-04
Release date:2010-07-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mutational studies of the peptidoglycan hydrolase FlgJ of Sphingomonas sp. strain A1
J.Basic Microbiol., 50, 2010
8AK8
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BU of 8ak8 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 4-hydroxybenzamide
Descriptor: 4-HYDROXYBENZAMIDE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKG
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BU of 8akg by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 4-amino-6-chlorobenzene-1,3-disulfonamide
Descriptor: 1,2-ETHANEDIOL, 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, CHLORIDE ION, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
5B6L
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BU of 5b6l by Molmil
Structure of Deg protease HhoA from Synechocystis sp. PCC 6803
Descriptor: Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ...
Authors:Dong, W, Wang, J, Liu, L.
Deposit date:2016-05-30
Release date:2016-09-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803
Febs Lett., 590, 2016
4A60
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BU of 4a60 by Molmil
Crystal structure of human testis-specific fatty acid binding protein 9 (FABP9)
Descriptor: 1,2-ETHANEDIOL, FATTY ACID-BINDING PROTEIN 9 TESTIS LIPID-BINDING PROTEIN, TLBP, ...
Authors:Muniz, J.R.C, Kiyani, W, Shrestha, L, Froese, D.S, Krojer, T, Vollmar, M, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, von Delft, F, Yue, W.W.
Deposit date:2011-10-31
Release date:2011-11-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Crystal Structure of the Human Fabp9A
To be Published
8AMC
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BU of 8amc by Molmil
Crystal Structure of cat allergen Fel d 4
Descriptor: Allergen Fel d 4, SULFATE ION
Authors:Schooltink, L, Sagmeister, T, Gottstein, N, Pavkov-Keller, T, Keller, W.
Deposit date:2022-08-03
Release date:2023-08-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of cat allergen Fel d 4
To Be Published
4ACS
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BU of 4acs by Molmil
Crystal structure of mutant GST A2-2 with enhanced catalytic efficiency with azathioprine
Descriptor: GLUTATHIONE, GLUTATHIONE S-TRANSFERASE A2
Authors:Zhang, W, Moden, O, Tars, K, Mannervik, B.
Deposit date:2011-12-19
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine.
Chem.Biol., 19, 2012
4ARA
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BU of 4ara by Molmil
Mus musculus Acetylcholinesterase in complex with (R)-C5685 at 2.5 A resolution.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(DIMETHYLAMINO)-N-{[(2R)-1-ETHYLPYRROLIDIN-2-YL]METHYL}-2-METHOXY-5-NITROBENZAMIDE, ...
Authors:Berg, L, Niemiec, M.S, Qian, W, Andersson, C.D, WittungStafshede, P, Ekstrom, F, Linusson, A.
Deposit date:2012-04-23
Release date:2012-11-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Similar But Different: Thermodynamic and Structural Characterization of a Pair of Enantiomers Binding to Acetylcholinesterase.
Angew.Chem.Int.Ed.Engl., 51, 2012
3JZ9
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BU of 3jz9 by Molmil
Crystal structure of the GEF domain of DrrA/SidM from Legionella pneumophila
Descriptor: Uncharacterized protein DrrA
Authors:Schoebel, S, Oesterlin, L.K, Blankenfeldt, W, Goody, R.S, Itzen, A.
Deposit date:2009-09-23
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity.
Mol.Cell, 36, 2009
3CKL
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BU of 3ckl by Molmil
Crystal structure of human cytosolic sulfotransferase SULT1B1 in complex with PAP and resveratrol
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, RESVERATROL, Sulfotransferase family cytosolic 1B member 1
Authors:Pan, P.W, Tempel, W, Dong, A, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2008-03-16
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human cytosolic sulfotransferase SULT1B1 in complex with PAP and resveratrol.
To be Published
5AYC
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BU of 5ayc by Molmil
Crystal structure of Ruminococcus albus 4-O-beta-D-mannosyl-D-glucose phosphorylase (RaMP1) in complexes with sulfate and 4-O-beta-D-mannosyl-D-glucose
Descriptor: 4-O-beta-D-mannosyl-D-glucose phosphorylase, SULFATE ION, beta-D-mannopyranose-(1-4)-beta-D-glucopyranose
Authors:Ye, Y, Saburi, W, Kato, K, Yao, M.
Deposit date:2015-08-13
Release date:2016-03-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the difference in substrate recognition of two mannoside phosphorylases from two GH130 subfamilies.
Febs Lett., 590, 2016
4ANQ
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BU of 4anq by Molmil
Structure of G1269A Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib
Descriptor: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, ALK TYROSINE KINASE RECEPTOR
Authors:McTigue, M, Deng, Y, Liu, W, Brooun, A.
Deposit date:2012-03-21
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib.
J.Med.Chem., 57, 2014
1P1E
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BU of 1p1e by Molmil
Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
Descriptor: Glutamate receptor interacting protein
Authors:Feng, W, Shi, Y, Li, M, Zhang, M.
Deposit date:2003-04-12
Release date:2003-11-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Nat.Struct.Biol., 10, 2003
3CXL
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BU of 3cxl by Molmil
Crystal structure of human chimerin 1 (CHN1)
Descriptor: N-chimerin, UNKNOWN ATOM OR ION, ZINC ION
Authors:Shen, L, Buck, M, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-04-24
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human chimerin 1 (CHN1).
To be Published
1OWH
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BU of 1owh by Molmil
Substituted 2-Naphthamidine Inhibitors of Urokinase
Descriptor: 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator
Authors:Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L.
Deposit date:2003-03-28
Release date:2003-09-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution.
J.Med.Chem., 47, 2004
3K8V
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BU of 3k8v by Molmil
Crysatl structure of a bacterial cell-surface flagellin N20C20
Descriptor: Flagellin homolog
Authors:Maruyama, Y, Momma, M, Hashimoto, W, Murata, K.
Deposit date:2009-10-15
Release date:2010-10-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of N- and C-terminal regions of flagellin
To be Published
3K9A
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BU of 3k9a by Molmil
Crystal Structure of HIV gp41 with MPER
Descriptor: HIV glycoprotein gp41
Authors:Shi, W, Han, D, Habte, H, Cho, M, Chance, M.R.
Deposit date:2009-10-15
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of HIV gp41 with the membrane-proximal external region
J.Biol.Chem., 285, 2010
1P8J
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BU of 1p8j by Molmil
CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ...
Authors:Henrich, S, Cameron, A, Bourenkov, G.P, Kiefersauer, R, Huber, R, Lindberg, I, Bode, W, Than, M.E.
Deposit date:2003-05-07
Release date:2003-07-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity
Nat.Struct.Biol., 10, 2003
5AIW
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BU of 5aiw by Molmil
NMR solution structure of the putative transfer protein TraH from Gram-positive conjugative plasmid pIP501
Descriptor: TRAH
Authors:Meyer, N.H, Fercher, C, Zangger, K, Keller, W.
Deposit date:2015-02-18
Release date:2016-03-09
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Virb8-Like Protein Trah is Crucial for DNA Transfer in Enterococcus Faecalis.
Sci.Rep., 6, 2016
8AZG
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BU of 8azg by Molmil
Crystal structure of MreB from Geobacillus stearothermophilus ATCC7953 in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell shape-determining protein MreB, GLYCEROL
Authors:Li de la Sierra-Gallay, I, Mao, W.
Deposit date:2022-09-06
Release date:2023-09-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:On the role of nucleotides and lipids in the polymerization of the actin homolog MreB from a Gram-positive bacterium.
Elife, 12, 2023
3JUI
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BU of 3jui by Molmil
Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
Descriptor: GLYCEROL, Translation initiation factor eIF-2B subunit epsilon
Authors:Wei, J, Xu, H, Zhang, C, Wang, M, Gao, F, Gong, W.
Deposit date:2009-09-15
Release date:2009-10-06
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
To be published
3K8W
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BU of 3k8w by Molmil
Crysatl structure of a bacterial cell-surface flagellin N20C45
Descriptor: Flagellin homolog
Authors:Maruyama, Y, Momma, M, Hashimoto, W, Murata, K.
Deposit date:2009-10-15
Release date:2010-10-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of N- and C-terminal regions of flagellin
To be Published
2FN5
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BU of 2fn5 by Molmil
NMR Structure of the Neurabin PDZ domain (502-594)
Descriptor: Neurabin-1
Authors:Dancheck, B, Peti, W.
Deposit date:2006-01-10
Release date:2007-01-09
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry, 46, 2007

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