1HW4
| STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE | 著者 | Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L. | 登録日 | 2001-01-09 | 公開日 | 2001-01-24 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors. J.Biol.Chem., 276, 2001
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3RRJ
| Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with P1,P5-Di(adenosine-5') pentaphosphate | 分子名称: | BIS(ADENOSINE)-5'-PENTAPHOSPHATE, Bifunctional NAD(P)H-hydrate repair enzyme Nnr, GLYCEROL, ... | 著者 | Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W. | 登録日 | 2011-04-29 | 公開日 | 2011-07-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
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1HQK
| CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS | 分子名称: | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE | 著者 | Zhang, X, Meining, W, Fischer, M, Bacher, A, Ladenstein, R. | 登録日 | 2000-12-18 | 公開日 | 2001-12-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons. J.Mol.Biol., 306, 2001
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2POC
| The crystal structure of isomerase domain of glucosamine-6-phosphate synthase from Candida albicans | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, ACETATE ION, SODIUM ION, ... | 著者 | Raczynska, J, Olchowy, J, Milewski, S, Rypniewski, W. | 登録日 | 2007-04-26 | 公開日 | 2007-09-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Crystal and Solution Studies of Glucosamine-6-phosphate Synthase from Candida albicans J.Mol.Biol., 372, 2007
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3N99
| Crystal structure of TM1086 | 分子名称: | CHLORIDE ION, uncharacterized protein TM1086 | 著者 | Chruszcz, M, Domagalski, M.J, Wang, S, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-05-28 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal structure of TM1086 To be Published
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1HYV
| HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM | 分子名称: | CHLORIDE ION, INTEGRASE, SULFATE ION, ... | 著者 | Molteni, V, Greenwald, J, Rhodes, D, Hwang, Y, Kwiatkowski, W, Bushman, F.D, Siegel, J.S, Choe, S. | 登録日 | 2001-01-22 | 公開日 | 2001-04-04 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain. Acta Crystallogr.,Sect.D, 57, 2001
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2PT9
| The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA) | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ... | 著者 | Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-08 | 公開日 | 2008-04-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J.Mol.Biol., 373, 2007
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1HYZ
| HIV INTEGRASE CORE DOMAIN COMPLEXED WITH A DERIVATIVE OF TETRAPHENYL ARSONIUM. | 分子名称: | (3,4-DIHYDROXY-PHENYL)-TRIPHENYL-ARSONIUM, CHLORIDE ION, INTEGRASE, ... | 著者 | Molteni, V, Greenwald, J, Rhodes, D, Hwang, Y, Kwiatkowski, W, Bushman, F.D, Siegel, J.S, Choe, S. | 登録日 | 2001-01-22 | 公開日 | 2001-04-04 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain. Acta Crystallogr.,Sect.D, 57, 2001
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3NGO
| Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA | 分子名称: | 5'-D(*AP*AP*AP*A)-3', CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION | 著者 | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | 登録日 | 2010-06-12 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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1OH2
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1OPK
| Structural basis for the auto-inhibition of c-Abl tyrosine kinase | 分子名称: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | 著者 | Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J. | 登録日 | 2003-03-06 | 公開日 | 2003-04-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell(Cambridge,Mass.), 112, 2003
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3ROX
| Crystal Structure of Mouse Apolipoprotein A-I Binding Protein in Complex with Theophylline | 分子名称: | Apolipoprotein A-I-binding protein, SULFATE ION, THEOPHYLLINE | 著者 | Shumilin, I.A, Jha, K.N, Cymborowski, M, Herr, J.C, Minor, W. | 登録日 | 2011-04-26 | 公開日 | 2012-07-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
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3RQ5
| Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis co-crystallized with ATP/Mg2+ and soaked with CoA | 分子名称: | ADP/ATP-dependent NAD(P)H-hydrate dehydratase, COENZYME A, GLYCEROL | 著者 | Shumilin, I.A, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-04-27 | 公開日 | 2011-07-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
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3RQH
| Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis in complex with P1,P6-Di(adenosine-5') hexaphosphate | 分子名称: | ADP/ATP-DEPENDENT NAD(P)H-HYDRATE DEHYDRATASE, MAGNESIUM ION, P1,P6-Di(adenosine-5') hexaphosphate | 著者 | Shumilin, I.A, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-04-28 | 公開日 | 2011-07-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
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1HJD
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3RQR
| Crystal structure of the RYR domain of the rabbit ryanodine receptor | 分子名称: | (UNK)(UNK)(UNK)(UNK), Ryanodine receptor 1 | 著者 | Nair, U.B, Li, W, Dong, A, Walker, J.R, Gramolini, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-04-28 | 公開日 | 2011-06-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Structural determination of the phosphorylation domain of the ryanodine receptor. Febs J., 279, 2012
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2PXX
| Human putative methyltransferase MGC2408 | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION, Uncharacterized protein MGC2408 | 著者 | Tempel, W, Wu, H, Dombrovsky, L, Zeng, H, Zhu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-14 | 公開日 | 2007-05-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene. Proteins, 74, 2009
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3R90
| Crystal structure of Malignant T cell-amplified sequence 1 protein | 分子名称: | GLYCEROL, Malignant T cell-amplified sequence 1, SULFATE ION, ... | 著者 | Hong, B, Dimov, S, Tempel, W, Tong, Y, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2011-03-24 | 公開日 | 2011-04-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of Malignant T cell-amplified sequence 1 protein to be published
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1NN7
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3RAO
| Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus ATCC 10987. | 分子名称: | Putative Luciferase-like Monooxygenase, SULFATE ION | 著者 | Domagalski, M.J, Chruszcz, M, Xu, X, Cui, H, Chin, S, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-03-28 | 公開日 | 2011-05-11 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus ATCC 10987. To be Published
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2PYP
| PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | 著者 | Genick, U.K, Borgstahl, G.E.O, Ng, K, Ren, Z, Pradervand, C, Burke, P, Srajer, V, Teng, T, Schildkamp, W, Mcree, D.E, Moffat, K, Getzoff, E.D. | 登録日 | 1997-02-03 | 公開日 | 1998-04-29 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of a protein photocycle intermediate by millisecond time-resolved crystallography. Science, 275, 1997
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3NKU
| Crystal structure of the N-terminal domain of DrrA/SidM from Legionella pneumophila | 分子名称: | DI(HYDROXYETHYL)ETHER, DrrA, TRIETHYLENE GLYCOL | 著者 | Mueller, M.P, Peters, H, Blankenfeldt, W, Goody, R.S, Itzen, A. | 登録日 | 2010-06-21 | 公開日 | 2010-08-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science, 329, 2010
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1F07
| STRUCTURE OF COENZYME F420 DEPENDENT TETRAHYDROMETHANOPTERIN REDUCTASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | 著者 | Shima, S, Warkentin, E, Grabarse, W, Thauer, R.K, Ermler, U. | 登録日 | 2000-05-15 | 公開日 | 2000-09-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of coenzyme F(420) dependent methylenetetrahydromethanopterin reductase from two methanogenic archaea. J.Mol.Biol., 300, 2000
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1NNX
| Structure of the hypothetical protein ygiW from E. coli. | 分子名称: | Protein ygiW, SULFATE ION | 著者 | Lehmann, C, Galkin, A, Pullalarevu, S, Sarikaya, E, Krajewski, W, Lim, K, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | 登録日 | 2003-01-14 | 公開日 | 2004-03-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of the hypothetical protein ygiW from E. coli. To be Published
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3RSY
| Cellobiose phosphorylase from Cellulomonas uda in complex with sulfate and glycerol | 分子名称: | Cellobiose phosphorylase, GLYCEROL, SULFATE ION | 著者 | Van Hoorebeke, A, Stout, J, Soetaert, W, Van Beeumen, J, Desmet, T, Savvides, S. | 登録日 | 2011-05-02 | 公開日 | 2012-06-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Cellobiose phosphorylase: reconstructing the structural itinerary along the catalytic pathway To be Published
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