1P6M
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![BU of 1p6m by Molmil](/molmil-images/mine/1p6m) | Bovine endothelial NOS heme domain with (4S)-N-(4-amino-5-[aminoethyl]aminopentyl)-N'-nitroguanidine bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | 著者 | Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | 登録日 | 2003-04-29 | 公開日 | 2004-01-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11, 2004
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2ZBU
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![BU of 2zbu by Molmil](/molmil-images/mine/2zbu) | Crystal structure of uncharacterized conserved protein from Thermotoga maritima | 分子名称: | ADENOSINE, Uncharacterized conserved protein | 著者 | Ebihara, A, Fujimoto, Y, Kagawa, W, Fujikawa, N, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-10-30 | 公開日 | 2007-11-13 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of uncharacterized conserved protein from Thermotoga maritima To be Published
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6EMT
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![BU of 6emt by Molmil](/molmil-images/mine/6emt) | |
6EMV
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4WQ5
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![BU of 4wq5 by Molmil](/molmil-images/mine/4wq5) | YgjD(V85E)-YeaZ heterodimer in complex with ATP | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ... | 著者 | Zhang, W. | 登録日 | 2014-10-21 | 公開日 | 2015-01-28 | 最終更新日 | 2015-02-25 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli. Nucleic Acids Res., 43, 2015
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1ONC
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![BU of 1onc by Molmil](/molmil-images/mine/1onc) | THE REFINED 1.7 ANGSTROMS X-RAY CRYSTALLOGRAPHIC STRUCTURE OF P-30, AN AMPHIBIAN RIBONUCLEASE WITH ANTI-TUMOR ACTIVITY | 分子名称: | P-30 PROTEIN, SULFATE ION | 著者 | Mosimann, S.C, Ardelt, W, James, M.N.G. | 登録日 | 1993-08-30 | 公開日 | 1994-01-31 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Refined 1.7 A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity. J.Mol.Biol., 236, 1994
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6EPC
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![BU of 6epc by Molmil](/molmil-images/mine/6epc) | Ground state 26S proteasome (GS2) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (12.3 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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1P58
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![BU of 1p58 by Molmil](/molmil-images/mine/1p58) | Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction | 分子名称: | Envelope protein M, Major envelope protein E | 著者 | Zhang, W, Chipman, P.R, Corver, J, Johnson, P.R, Zhang, Y, Mukhopadhyay, S, Baker, T.S, Strauss, J.H, Rossmann, M.G, Kuhn, R.J. | 登録日 | 2003-04-25 | 公開日 | 2003-11-04 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Visualization of membrane protein domains by cryo-electron microscopy of dengue virus Nat.Struct.Biol., 10, 2003
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2ZM3
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![BU of 2zm3 by Molmil](/molmil-images/mine/2zm3) | Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor | 分子名称: | (4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione, Insulin-like growth factor 1 receptor | 著者 | Xu, W, Mayer, S.C, Boschelli, F, Johnson, M, Dwyer, B. | 登録日 | 2008-04-10 | 公開日 | 2008-06-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment Bioorg.Med.Chem.Lett., 18, 2008
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4WRR
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![BU of 4wrr by Molmil](/molmil-images/mine/4wrr) | A putative diacylglycerol kinase from Bacillus anthracis str. Sterne | 分子名称: | MAGNESIUM ION, putative diacylglycerol kinase | 著者 | Hou, J, Zheng, H, Cooper, D.R, Zimmerman, M.D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-10-24 | 公開日 | 2014-11-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne to be published
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6OEM
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![BU of 6oem by Molmil](/molmil-images/mine/6oem) | Cryo-EM structure of mouse RAG1/2 PRC complex (DNA0) | 分子名称: | DNA (46-MER), DNA (57-MER), High mobility group protein B1, ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2020-02-26 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
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2ZUY
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![BU of 2zuy by Molmil](/molmil-images/mine/2zuy) | Crystal structure of exotype rhamnogalacturonan lyase YesX | 分子名称: | CALCIUM ION, YesX protein | 著者 | Ochiai, A, Itoh, T, Mikami, B, Hashimoto, W, Murata, K. | 登録日 | 2008-10-28 | 公開日 | 2009-02-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural determinants responsible for substrate recognition and mode of action in family 11 polysaccharide lyases J.Biol.Chem., 284, 2009
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4X0O
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![BU of 4x0o by Molmil](/molmil-images/mine/4x0o) | Beta-ketoacyl-(acyl carrier protein) synthase III-2 (FabH2) from Vibrio cholerae soaked with Acetyl-CoA | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2, COENZYME A, MALONATE ION, ... | 著者 | Hou, J, Chruszcz, M, Zheng, H, Cooper, D.R, Chordia, M.D, Zimmerman, M.D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-11-21 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and enzymatic studies of beta-ketoacyl-(acyl carrier protein) synthase III (FabH) from Vibrio cholerae to be published
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2Z38
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2Z37
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2Z4R
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![BU of 2z4r by Molmil](/molmil-images/mine/2z4r) | Crystal structure of domain III from the Thermotoga maritima replication initiation protein DnaA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromosomal replication initiator protein dnaA, MAGNESIUM ION | 著者 | Fujikawa, N, Ozaki, S, Kagawa, W, Park, S.-Y, Katayama, T, Kurumizaka, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-06-25 | 公開日 | 2008-02-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | A Common Mechanism for the ATP-DnaA-dependent Formation of Open Complexes at the Replication Origin J.Biol.Chem., 283, 2008
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2Z6H
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![BU of 2z6h by Molmil](/molmil-images/mine/2z6h) | Crystal Structure of Beta-Catenin Armadillo Repeat Region and Its C-Terminal domain | 分子名称: | Catenin beta-1 | 著者 | Xing, Y, Takemaru, K, Liu, J, Zheng, J, Moon, R, Xu, W. | 登録日 | 2007-08-01 | 公開日 | 2008-02-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of a Full-Length beta-Catenin Structure, 16, 2008
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4X8B
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![BU of 4x8b by Molmil](/molmil-images/mine/4x8b) | Ergothioneine-biosynthetic sulfoxide synthase EgtB, apo form | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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4WKT
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![BU of 4wkt by Molmil](/molmil-images/mine/4wkt) | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ | 分子名称: | 1-BUTANE BORONIC ACID, Acyl-homoserine lactone acylase PvdQ, GLYCEROL | 著者 | Wu, R, Clevenger, K.D, Fast, W, Liu, D. | 登録日 | 2014-10-03 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.782 Å) | 主引用文献 | n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ. Biochemistry, 53, 2014
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6ENZ
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![BU of 6enz by Molmil](/molmil-images/mine/6enz) | Crystal structure of mouse GADL1 | 分子名称: | Acidic amino acid decarboxylase GADL1, PYRIDOXAL-5'-PHOSPHATE | 著者 | Raasakka, A, Mahootchi, E, Winge, I, Luan, W, Kursula, P, Haavik, J. | 登録日 | 2017-10-07 | 公開日 | 2018-01-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the mouse acidic amino acid decarboxylase GADL1. Acta Crystallogr F Struct Biol Commun, 74, 2018
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1OS5
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![BU of 1os5 by Molmil](/molmil-images/mine/1os5) | Crystal structure of HCV NS5B RNA polymerase complexed with a novel non-competitive inhibitor. | 分子名称: | 3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE, Hepatitis C virus NS5B RNA polymerase | 著者 | Love, R.A, Parge, H.E, Yu, X, Hickey, M.J, Diehl, W, Gao, J, Wriggers, H, Ekker, A, Wang, L, Thomson, J.A, Dragovich, P.S, Fuhrman, S.A. | 登録日 | 2003-03-18 | 公開日 | 2004-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme. J.Virol., 77, 2003
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3F5O
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![BU of 3f5o by Molmil](/molmil-images/mine/3f5o) | Crystal Structure of hTHEM2(undecan-2-one-CoA) complex | 分子名称: | CHLORIDE ION, COENZYME A, HEXAETHYLENE GLYCOL, ... | 著者 | Xu, H, Gong, W. | 登録日 | 2008-11-04 | 公開日 | 2009-08-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis Biochemistry, 48, 2009
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380D
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![BU of 380d by Molmil](/molmil-images/mine/380d) | BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES | 分子名称: | 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*CP*GP*(G49)P*(CBR)P*CP*G)-3') | 著者 | Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J. | 登録日 | 1998-02-18 | 公開日 | 1998-07-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26, 1998
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6OEP
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![BU of 6oep by Molmil](/molmil-images/mine/6oep) | Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
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1P6H
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![BU of 1p6h by Molmil](/molmil-images/mine/1p6h) | Rat neuronal NOS heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE, ... | 著者 | Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | 登録日 | 2003-04-29 | 公開日 | 2004-01-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11, 2004
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