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PDB: 34877 results

1OJ4
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Ternary complex of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Descriptor: 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLORIDE ION, ...
Authors:Miallau, L, Alphey, M.S, Hunter, W.N.
Deposit date:2003-06-30
Release date:2003-07-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase
Proc.Natl.Acad.Sci.USA, 100, 2003
8SW1
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Puromycin-sensitive aminopeptidase with bound peptide
Descriptor: Polyglutamine peptide, Puromycin-sensitive aminopeptidase, ZINC ION
Authors:Rodgers, D.W, Madabushi, S.
Deposit date:2023-05-17
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structure of puromycin-sensitive aminopeptidase and polyglutamine binding.
Plos One, 18, 2023
3VIJ
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BU of 3vij by Molmil
Crystal structure of beta-glucosidase from termite Neotermes koshunensis in complex with glucose
Descriptor: Beta-glucosidase, CHLORIDE ION, GLYCEROL, ...
Authors:Jeng, W.Y, Liu, C.I, Wang, A.H.J.
Deposit date:2011-10-03
Release date:2012-07-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:High-resolution structures of Neotermes koshunensis beta-glucosidase mutants provide insights into the catalytic mechanism and the synthesis of glucoconjugates
Acta Crystallogr.,Sect.D, 68, 2012
3VJ8
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BU of 3vj8 by Molmil
Crystal structure of the human squalene synthase
Descriptor: Squalene synthase
Authors:Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
Deposit date:2011-10-14
Release date:2012-04-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
4A6N
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BU of 4a6n by Molmil
STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH TIGECYCLINE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TETX2 PROTEIN, ...
Authors:Volkers, G, Palm, G.J, Weiss, M.S, Hinrichs, W.
Deposit date:2011-11-07
Release date:2012-11-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Putative Dioxygen-Binding Sites and Recognition of Tigecycline and Minocycline in the Tetracycline-Degrading Monooxygenase Tetx
Acta Crystallogr.,Sect.D, 69, 2013
3NIK
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BU of 3nik by Molmil
The structure of UBR box (REAA)
Descriptor: E3 ubiquitin-protein ligase UBR1, Peptide REAA, ZINC ION
Authors:Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K.
Deposit date:2010-06-16
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases
Nat.Struct.Mol.Biol., 17, 2010
4MWA
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BU of 4mwa by Molmil
1.85 Angstrom Crystal Structure of GCPE Protein from Bacillus anthracis
Descriptor: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, CHLORIDE ION, SULFATE ION
Authors:Minasov, G, Wawrzak, Z, Brunzelle, J.S, Xu, X, Cui, H, Maltseva, N, Bishop, B, Kwon, K, Savchenko, A, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-09-24
Release date:2013-10-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:1.85 Angstrom Crystal Structure of GCPE Protein from Bacillus anthracis.
TO BE PUBLISHED
3N8H
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BU of 3n8h by Molmil
Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis
Descriptor: ACETIC ACID, ADENOSINE MONOPHOSPHATE, GLYCEROL, ...
Authors:Maltseva, N, Kim, Y, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-05-28
Release date:2010-06-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis
To be Published, 2010
1G0M
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BU of 1g0m by Molmil
CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152I
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME)
Authors:Xu, J, Baase, W.A, Quillin, M.L, Matthews, B.W.
Deposit date:2000-10-06
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein Sci., 10, 2001
1FVT
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BU of 1fvt by Molmil
THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH AN OXINDOLE INHIBITOR
Descriptor: 4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzene-1-sulfonamide, CELL DIVISION PROTEIN KINASE 2
Authors:Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K.
Deposit date:2000-09-20
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
Science, 291, 2001
6DOC
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BU of 6doc by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 240 s at 21 C
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2018-06-09
Release date:2018-08-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6DOO
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BU of 6doo by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 100 mM K+ for 120 s at 21 C (dataset 2)
Descriptor: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ...
Authors:Samara, N.L, Yang, W.
Deposit date:2018-06-09
Release date:2018-08-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
3NKV
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BU of 3nkv by Molmil
Crystal structure of Rab1b covalently modified with AMP at Y77
Descriptor: ADENOSINE MONOPHOSPHATE, BARIUM ION, MAGNESIUM ION, ...
Authors:Mueller, M.P, Peters, H, Blankenfeldt, W, Goody, R.S, Itzen, A.
Deposit date:2010-06-21
Release date:2010-08-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
Science, 329, 2010
7DO1
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BU of 7do1 by Molmil
Solution structure of a heteromolecular telomeric (3+1) G-quadruplex containing right loop progression
Descriptor: DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*G)-3')
Authors:Fu, W.Q, Jing, H.T, Zhang, N.
Deposit date:2020-12-11
Release date:2021-09-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two coexisting pseudo-mirror heteromolecular telomeric G-quadruplexes in opposite loop progressions differentially recognized by a low equivalent of Thioflavin T.
Nucleic Acids Res., 49, 2021
8STY
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BU of 8sty by Molmil
Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI60
Descriptor: 3C-like proteinase nsp5, benzyl (3S)-3-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamoyl)-2-azaspiro[4.4]nonane-2-carboxylate
Authors:Blankenship, L.B, Liu, W.R.
Deposit date:2023-05-11
Release date:2023-08-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease.
J.Med.Chem., 66, 2023
7D11
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BU of 7d11 by Molmil
Solution structure of a WKRY DNA-binding domain
Descriptor: WRKY transcription factor 1, ZINC ION
Authors:Li, Q.W, Hu, Y.F, Jin, C.W.
Deposit date:2020-09-12
Release date:2021-09-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a WKRY DNA-binding domain
To Be Published
8T0G
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BU of 8t0g by Molmil
Backbone Dialkylation in Peptide Hairpins: Natural Backbone Prototype
Descriptor: Immunoglobulin G-binding protein G
Authors:Heath, S.L, Horne, W.S, Lengyel, G.A.
Deposit date:2023-06-01
Release date:2023-08-16
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
7KWK
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BU of 7kwk by Molmil
DNA-DB1879 complex: The DNA sequence 5'-CGCGAATTCGCG-3' presents a binding site for the heterocyclic small molecule (DB1879).
Descriptor: 2-[5-(4-carbamimidoylphenyl)thiophen-2-yl]-1H-indole-6-carboximidamide, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Ogbonna, E, Fang, Z, Wilson, D.W.
Deposit date:2020-12-01
Release date:2021-12-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines.
Bioorg.Med.Chem., 68, 2022
8T0H
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BU of 8t0h by Molmil
Backbone Dialkylation in Peptide Hairpins: (S)-Ethylpropylglycine variant
Descriptor: Immunoglobulin G-binding protein G
Authors:Heath, S.L, Horne, W.S, Lengyel, G.A.
Deposit date:2023-06-01
Release date:2023-08-16
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8STZ
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BU of 8stz by Molmil
Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI37
Descriptor: 3C-like proteinase nsp5, benzyl (3S)-3-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamoyl)-2-azaspiro[4.5]decane-2-carboxylate
Authors:Blankenship, L.B, Liu, W.R.
Deposit date:2023-05-11
Release date:2023-08-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease.
J.Med.Chem., 66, 2023
8T0I
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BU of 8t0i by Molmil
Backbone Dialkylation in Peptide Hairpins: (R)-Ethylpropylglycine variant
Descriptor: Immunoglobulin G-binding protein G
Authors:Heath, S.L, Horne, W.S, Lengyel, G.A.
Deposit date:2023-06-01
Release date:2023-08-16
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
6DEW
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BU of 6dew by Molmil
Structure of human COQ9 protein with bound isoprene.
Descriptor: (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, (2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, ...
Authors:Bingman, C.A, Lohman, D.C, Smith, R.W, Pagliarini, D.J.
Deposit date:2018-05-13
Release date:2019-02-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis.
Mol.Cell, 73, 2019
2VA6
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BU of 2va6 by Molmil
X-ray crystal structure of beta secretase complexed with compound 24
Descriptor: (6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one, BETA SECRETASE 1, IODIDE ION
Authors:Edwards, P.D, Albert, J.S, Sylvester, M, Aharony, D, Andisik, D, Callaghan, O, Campbell, J.B, Carr, R.A, Chessari, G, Congreve, M, Frederickson, M, Folmer, R.H.A, Geschwindner, S, Koether, G, Kolmodin, K, Krumrine, J, Mauger, R.C, Murray, C.W, Olsson, L.L, Patel, S, Spear, N, Tian, G.
Deposit date:2007-08-30
Release date:2007-11-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine Beta-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency.
J.Med.Chem., 50, 2007
8TJ2
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BU of 8tj2 by Molmil
CryoEM structure of Myxococcus xanthus type IV pilus
Descriptor: Type IV major pilin protein PilA
Authors:Zheng, W, Egelman, E.H.
Deposit date:2023-07-20
Release date:2023-08-09
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Tight-packing of large pilin subunits provides distinct structural and mechanical properties for the Myxococcus xanthus type IVa pilus.
Proc.Natl.Acad.Sci.USA, 121, 2024
1FK2
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STRUCTURAL BASIS OF NON-SPECIFIC LIPID BINDING IN MAIZE LIPID-TRANSFER PROTEIN COMPLEXES WITH MYRISTIC ACID REVEALED BY HIGH-RESOLUTION X-RAY CRYSTALLOGRAPHY
Descriptor: FORMIC ACID, MYRISTIC ACID, NONSPECIFIC LIPID-TRANSFER PROTEIN
Authors:Han, G.W, Lee, J.Y, Song, H.K, Shin, D.H, Suh, S.W.
Deposit date:2000-08-09
Release date:2001-06-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography.
J.Mol.Biol., 308, 2001

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