1RF6
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![BU of 1rf6 by Molmil](/molmil-images/mine/1rf6) | Structural Studies of Streptococcus pneumoniae EPSP Synthase in S3P-GLP Bound State | Descriptor: | 5-enolpyruvylshikimate-3-phosphate synthase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE | Authors: | Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C. | Deposit date: | 2003-11-07 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state. Mol.Microbiol., 51, 2004
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1RHX
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1RJK
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![BU of 1rjk by Molmil](/molmil-images/mine/1rjk) | crystal structure of the rat vitamin D receptor ligand binding domain complexed with 2MD and a synthetic peptide containing the NR2 box of DRIP 205 | Descriptor: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIO L, Peroxisome proliferator-activated receptor binding protein, Vitamin D3 receptor | Authors: | Vanhooke, J.L, Benning, M.M, Bauer, C.B, Pike, J.W, DeLuca, H.F. | Deposit date: | 2003-11-19 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide Biochemistry, 43, 2004
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8SFW
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![BU of 8sfw by Molmil](/molmil-images/mine/8sfw) | Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with quercetin | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, UDP-glycosyltransferase 202A2, URIDINE-5'-DIPHOSPHATE | Authors: | Arriaza, R.H, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M. | Deposit date: | 2023-04-11 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with quercetin To Be Published
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8SGG
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![BU of 8sgg by Molmil](/molmil-images/mine/8sgg) | Crystal structure of Cy137D09, a monoclonal antibody isolated from macaques immunized with an Epstein-Barr virus glycoprotein 350 (gp350) nanoparticle vaccine | Descriptor: | Cy137D09 Fab heavy chain, Cy137D09 Fab light chain, GLYCEROL | Authors: | Joyce, M.G, Jensen, J.L, Chen, W.H, Kanekiyo, M. | Deposit date: | 2023-04-12 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of Cy137D09, a monoclonal antibody isolated from macaques immunized with an Epstein-Barr virus glycoprotein 350 (gp350) nanoparticle vaccine To Be Published
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8S9X
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1RQI
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![BU of 1rqi by Molmil](/molmil-images/mine/1rqi) | Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Dimethylallyl S-Thiolodiphosphate | Descriptor: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, DIPHOSPHATE, Geranyltranstransferase, ... | Authors: | Hosfield, D.J, Zhang, Y, Dougan, D.R, Brooun, A, Tari, L.W, Swanson, R.V, Finn, J. | Deposit date: | 2003-12-05 | Release date: | 2004-03-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis J.Biol.Chem., 279, 2004
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1RQX
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![BU of 1rqx by Molmil](/molmil-images/mine/1rqx) | Crystal structure of ACC Deaminase complexed with Inhibitor | Descriptor: | 1-AMINOCYCLOPROPYLPHOSPHONATE, 1-aminocyclopropane-1-carboxylate deaminase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Karthikeyan, S, Zhao, Z, Kao, C.L, Zhou, Q, Tao, Z, Zhang, H, Liu, H.W. | Deposit date: | 2003-12-07 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural analysis of 1-aminocyclopropane-1-carboxylate deaminase: observation of an aminyl intermediate and identification of Tyr 294 as the active-site nucleophile. Angew.Chem.Int.Ed.Engl., 43, 2004
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1RRW
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![BU of 1rrw by Molmil](/molmil-images/mine/1rrw) | DHNA complexed with 9-methylguanine | Descriptor: | 9-METHYLGUANINE, Dihydroneopterin aldolase | Authors: | Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. | Deposit date: | 2003-12-09 | Release date: | 2004-03-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization. J.Med.Chem., 47, 2004
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1RS2
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![BU of 1rs2 by Molmil](/molmil-images/mine/1rs2) | DHNA complex with 8-Amino-1,3-dimethyl-3,7-dihydropurine-2,6-dione | Descriptor: | 8-AMINO-1,3-DIMETHYL-3,7-DIHYDROPURINE-2,6-DIONE, Dihydroneopterin aldolase | Authors: | Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. | Deposit date: | 2003-12-09 | Release date: | 2004-03-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization. J.Med.Chem., 47, 2004
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1RSZ
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![BU of 1rsz by Molmil](/molmil-images/mine/1rsz) | Structure of human purine nucleoside phosphorylase in complex with DADMe-Immucillin-H and sulfate | Descriptor: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION | Authors: | Shi, W, Lewandowicz, A, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L. | Deposit date: | 2003-12-10 | Release date: | 2005-02-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural comparison of human and malarial purine nucleoside phosphorylases To be Published
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1RWF
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![BU of 1rwf by Molmil](/molmil-images/mine/1rwf) | Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide | Descriptor: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, PHOSPHATE ION, SODIUM ION, ... | Authors: | Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M. | Deposit date: | 2003-12-16 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism J.Mol.Biol., 337, 2004
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8S9T
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![BU of 8s9t by Molmil](/molmil-images/mine/8s9t) | CRISPR-Cas type III-D effector complex | Descriptor: | CRISPR RNA, Cas10, Cas7-2x, ... | Authors: | Schwartz, E.A, Taylor, D.W. | Deposit date: | 2023-03-30 | Release date: | 2024-04-24 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nat Commun, 15, 2024
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8S9U
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1RWG
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![BU of 1rwg by Molmil](/molmil-images/mine/1rwg) | Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide | Descriptor: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, PHOSPHATE ION, SODIUM ION, ... | Authors: | Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M. | Deposit date: | 2003-12-16 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism J.Mol.Biol., 337, 2004
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8SQH
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![BU of 8sqh by Molmil](/molmil-images/mine/8sqh) | SpRY-Cas9:gRNA complex targeting TTC PAM DNA | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-05-04 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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1R1G
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8SRS
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![BU of 8srs by Molmil](/molmil-images/mine/8srs) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-05-06 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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1R3C
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![BU of 1r3c by Molmil](/molmil-images/mine/1r3c) | THE STRUCTURE OF P38ALPHA C162S MUTANT | Descriptor: | MAGNESIUM ION, Mitogen-activated protein kinase 14 | Authors: | Patel, S.B, Cameron, P.M, Frantz-Wattley, B, O'Neill, E, Becker, J.W, Scapin, G. | Deposit date: | 2003-10-01 | Release date: | 2004-01-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Lattice stabilization and enhanced diffraction in human p38 alpha crystals by protein engineering. Biochim.Biophys.Acta, 1696, 2004
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1R3O
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![BU of 1r3o by Molmil](/molmil-images/mine/1r3o) | Crystal structure of the first RNA duplex in L-conformation at 1.9A resolution | Descriptor: | L-RNA | Authors: | Vallazza, M, Perbandt, M, Klussmann, S, Rypniewski, W, Erdmann, V.A, Betzel, C. | Deposit date: | 2003-10-02 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | First look at RNA in L-configuration. Acta Crystallogr.,Sect.D, 60, 2004
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1R7J
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![BU of 1r7j by Molmil](/molmil-images/mine/1r7j) | Crystal structure of the DNA-binding protein Sso10a from Sulfolobus solfataricus | Descriptor: | Conserved hypothetical protein Sso10a | Authors: | Chen, L, Chen, L.R, Zhou, X.E, Wang, Y, Kahsai, M.A, Clark, A.T, Edmondson, S.P, Liu, Z.-J, Rose, J.P, Wang, B.C, Shriver, J.W, Meehan, E.J, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2003-10-21 | Release date: | 2004-07-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | The hyperthermophile protein Sso10a is a dimer of winged helix DNA-binding domains linked by an antiparallel coiled coil rod. J.Mol.Biol., 341, 2004
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8SPQ
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![BU of 8spq by Molmil](/molmil-images/mine/8spq) | SpRY-Cas9:gRNA complex targeting TGG PAM DNA | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2023-05-03 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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1RMO
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![BU of 1rmo by Molmil](/molmil-images/mine/1rmo) | Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code | Descriptor: | wunen-nonfunctional GFP fusion protein | Authors: | Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T. | Deposit date: | 2003-11-28 | Release date: | 2004-06-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code Biol.Chem., 385, 2004
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1RF4
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![BU of 1rf4 by Molmil](/molmil-images/mine/1rf4) | Structural Studies of Streptococcus pneumoniae EPSP Synthase, Tetrahedral intermediate Bound State | Descriptor: | (3R,4S,5R)-5-{[(1R)-1-CARBOXY-2-FLUORO-1-(PHOSPHONOOXY)ETHYL]OXY}-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 5-enolpyruvylshikimate-3-phosphate synthase | Authors: | Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C. | Deposit date: | 2003-11-07 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state. Mol.Microbiol., 51, 2004
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1RQN
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![BU of 1rqn by Molmil](/molmil-images/mine/1rqn) | Phosphonoacetaldehyde hydrolase complexed with magnesium | Descriptor: | MAGNESIUM ION, Phosphonoacetaldehyde Hydrolase | Authors: | Morais, M.C, Zhang, G, Zhang, W, Olsen, D.B, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2003-12-05 | Release date: | 2004-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-ray crystallographic and site-directed mutagenesis
analysis of the mechanism of Schiff-base formation in
phosphonoacetaldehyde hydrolase catalysis J.Biol.Chem., 279, 2004
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