2AQU
 
 | | Structure of HIV-1 protease bound to atazanavir | | Descriptor: | (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, HIV-1 Protease | | Authors: | Clemente, J.C, Coman, R.M, Thiaville, M.M, Janka, L.K, Jeung, J.A, Nukoolkarn, S, Govindasamy, L, Agbandje-McKenna, M, McKenna, R, Leelamanit, W, Goodenow, M.M, Dunn, B.M. | | Deposit date: | 2005-08-18 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.
Biochemistry, 45, 2006
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8HI5
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2AZQ
 | | Crystal Structure of Catechol 1,2-Dioxygenase from Pseudomonas arvilla C-1 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, FE (III) ION, catechol 1,2-dioxygenase | | Authors: | Earhart, C.A, Vetting, M.W, Gosu, R, Michaud-Soret, I, Que, L, Ohlendorf, D.H. | | Deposit date: | 2005-09-12 | | Release date: | 2005-10-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of catechol 1,2-dioxygenase from Pseudomonas arvilla
Biochem.Biophys.Res.Commun., 338, 2005
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8GZF
 | | Crystal Structure of METTL9-SAH | | Descriptor: | Protein-L-histidine N-pros-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Zhao, W.T, Li, H.T. | | Deposit date: | 2022-09-26 | | Release date: | 2023-05-31 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular basis for protein histidine N1-specific methylation of the "His-x-His" motifs by METTL9.
Cell Insight, 2, 2023
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2AS3
 | | cytochrome c peroxidase in complex with phenol | | Descriptor: | Cytochrome c peroxidase, mitochondrial, PHENOL, ... | | Authors: | Brenk, R, Vetter, S.W, Boyce, S.E, Goodin, D.B, Shoichet, B.K. | | Deposit date: | 2005-08-22 | | Release date: | 2006-04-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Probing molecular docking in a charged model binding site.
J.Mol.Biol., 357, 2006
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2B3L
 | | Crystal structure of type I human methionine aminopeptidase in the apo form | | Descriptor: | ACETIC ACID, GLYCEROL, Methionine aminopeptidase 1, ... | | Authors: | Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W. | | Deposit date: | 2005-09-20 | | Release date: | 2005-11-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases(,).
Biochemistry, 44, 2005
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2B0H
 | | Solution structure of VBS3 fragment of talin | | Descriptor: | Talin-1 | | Authors: | Gingras, A.R, Vogel, K.P, Steinhoff, H.J, Ziegler, W.H, Patel, B, Emsley, J, Critchley, D.R, Roberts, G.C, Barsukov, I.L. | | Deposit date: | 2005-09-14 | | Release date: | 2006-01-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
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2B2T
 | | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3 | | Descriptor: | Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail | | Authors: | Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S. | | Deposit date: | 2005-09-19 | | Release date: | 2005-12-27 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
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8SFT
 | | Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with kaempferol | | Descriptor: | 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, SULFATE ION, UDP-glycosyltransferase 202A2, ... | | Authors: | Arriaza, R.H, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M. | | Deposit date: | 2023-04-11 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with kaempferol
To Be Published
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2B50
 | | Human Nuclear Receptor-Ligand Complex 2 | | Descriptor: | CALCIUM ION, Peroxisome proliferator activated receptor delta, VACCENIC ACID, ... | | Authors: | Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N. | | Deposit date: | 2005-09-27 | | Release date: | 2006-02-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Recombinant Human PPAR-beta/delta Ligand-binding Domain is Locked in an Activated Conformation by Endogenous Fatty Acids
J.Mol.Biol., 356, 2006
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2B77
 | | Human transthyretin (TTR) complexed with Diflunisal analogues- TTR.2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID | | Descriptor: | 2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID, Transthyretin | | Authors: | Palaninathan, S.K, Kelly, J.W, Sacchettini, J.C. | | Deposit date: | 2005-10-03 | | Release date: | 2005-10-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis.
J.Med.Chem., 47, 2004
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8HI6
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8SWM
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8SXD
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2AMI
 | | Solution Structure Of The Calcium-loaded N-Terminal Sensor Domain Of Centrin | | Descriptor: | Caltractin | | Authors: | Hu, H.T, Fagan, P.A, Bunick, C.G, Sheehan, J.H, Chazin, W.J. | | Deposit date: | 2005-08-09 | | Release date: | 2005-08-23 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function.
J.Biol.Chem., 281, 2006
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8SGN
 | | Crystal structure of Epstein-Barr virus glycoprotein 350 (gp350) in complex with Cy651H02, a monoclonal antibody isolated from macaques immunized with a gp350 nanoparticle vaccine | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Joyce, M.G, Jensen, J.L, Chen, W.H, Kanekiyo, M. | | Deposit date: | 2023-04-12 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of Epstein-Barr virus glycoprotein 350 (gp350) in complex with Cy651H02, a monoclonal antibody isolated from macaques immunized with a gp350 nanoparticle vaccine
To Be Published
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2AOI
 | | Crystal structure analysis of HIV-1 protease with a substrate analog P1-P6 | | Descriptor: | PEPTIDE INHIBITOR, POL POLYPROTEIN, SULFATE ION | | Authors: | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T. | | Deposit date: | 2005-08-12 | | Release date: | 2006-01-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
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2AS6
 | | cytochrome c peroxidase in complex with cyclopentylamine | | Descriptor: | CYCLOPENTANAMINE, Cytochrome c peroxidase, mitochondrial, ... | | Authors: | Brenk, R, Vetter, S.W, Boyce, S.E, Goodin, D.B, Shoichet, B.K. | | Deposit date: | 2005-08-22 | | Release date: | 2006-04-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Probing molecular docking in a charged model binding site.
J.Mol.Biol., 357, 2006
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2AVM
 | | Kinetics, stability, and structural changes in high resolution crystal structures of HIV-1 protease with drug resistant mutations L24I, I50V, AND G73S | | Descriptor: | ACETIC ACID, GLYCEROL, HIV-1 protease, ... | | Authors: | Liu, F, Boross, P.I, Wang, Y.F, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T. | | Deposit date: | 2005-08-30 | | Release date: | 2006-01-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S.
J.Mol.Biol., 354, 2005
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2AZ4
 | | Crystal Structure of a Protein of Unknown Function from Enterococcus faecalis V583 | | Descriptor: | ZINC ION, hypothetical protein EF2904 | | Authors: | Zhang, R, Maltseva, N, Moy, S, Collart, F, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2005-09-09 | | Release date: | 2005-10-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The 2.0 A crystal structure of a hypothetical protein from Enterococcus faecalis V583
To be Published
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2AU4
 | | Class I GTP aptamer | | Descriptor: | Class I RNA aptamer to GTP, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Carothers, J.M, Davis, J.H, Chou, J.J, Szostak, J.W. | | Deposit date: | 2005-08-26 | | Release date: | 2006-03-28 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of an informationally complex high-affinity RNA aptamer to GTP.
Rna, 12, 2006
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2AVS
 | | kinetics, stability, and structural changes in high resolution crystal structures of HIV-1 protease with drug resistant mutations L24I, I50V, and G73S | | Descriptor: | ACETIC ACID, DIMETHYL SULFOXIDE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, ... | | Authors: | Liu, F, Boross, P.I, Wang, Y.F, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T. | | Deposit date: | 2005-08-30 | | Release date: | 2006-01-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S.
J.Mol.Biol., 354, 2005
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2AXR
 | | Crystal structure of glucooligosaccharide oxidase from Acremonium strictum: a novel flavinylation of 6-S-cysteinyl, 8alpha-N1-histidyl FAD | | Descriptor: | (2R,3R,4R,5R)-4,5-dihydroxy-2-(hydroxymethyl)-6-oxopiperidin-3-yl beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Huang, C.-H, Lai, W.-L, Vasella, A, Tsai, Y.-C, Liaw, S.-H. | | Deposit date: | 2005-09-05 | | Release date: | 2005-09-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystal Structure of Glucooligosaccharide Oxidase from Acremonium strictum: A NOVEL FLAVINYLATION OF 6-S-CYSTEINYL, 8{alpha}-N1-HISTIDYL FAD
J.Biol.Chem., 280, 2005
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8SRA
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium | | Descriptor: | CALCIUM ION, CHOLESTEROL, TRPM2 chanzyme | | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
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2B0Y
 | | Solution Structure of a peptide mimetic of the fourth cytoplasmic loop of the G-protein coupled CB1 cannabinoid receptor | | Descriptor: | Cannabinoid receptor 1 | | Authors: | Grace, C.R, Cowsik, S.M, Shim, J.Y, Welsh, W.J, Howlett, A.C. | | Deposit date: | 2005-09-15 | | Release date: | 2006-08-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment.
J.Struct.Biol., 159, 2007
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