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PDB: 34447 件

6R7Y
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CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (low Ca2+, closed form)
分子名称: Anoctamin-10, CALCIUM ION
著者Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
登録日2019-03-29
公開日2019-05-01
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
6R39
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T. brucei FPPS in complex with 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid
分子名称: 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W.
登録日2019-03-19
公開日2020-04-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery
Thesis, 2019
4W86
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Crystal structure of XEG5A, a GH5 xyloglucan-specific endo-beta-1,4-glucanase from ruminal metagenomic library, in complex with glucose and TRIS
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Xyloglucan-specific endo-beta-1,4-glucanase, ...
著者Santos, C.R, Cordeiro, R.L, Wong, D.W.S, Murakami, M.T.
登録日2014-08-22
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural Basis for Xyloglucan Specificity and alpha-d-Xylp(1 6)-d-Glcp Recognition at the -1 Subsite within the GH5 Family.
Biochemistry, 54, 2015
6RCR
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TETR(D) H100A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-11
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
4WCZ
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Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
分子名称: Enoyl-CoA hydratase/isomerase
著者Tkaczuk, K.L, Cooper, D.R, Chapman, H.C, Niedzialkowska, E, Cymborowski, M.T, Hillerich, B.S, Stead, M, Ahmed, M, Hammonds, J, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-09-05
公開日2014-12-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
to be published
6L5A
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The structure of the UdgX mutant H109E at a pre-excision state
分子名称: GLYCEROL, IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
著者Xie, W, Tu, J, Zeng, H.
登録日2019-10-22
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.80007327 Å)
主引用文献Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
4W4R
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BU of 4w4r by Molmil
Crystal structure of ent-kaurene synthase BJKS from bradyrhizobium japonicum
分子名称: Uncharacterized protein blr2150
著者Liu, W, Zheng, Y, Huang, C.H, Ko, T.P, Guo, R.T.
登録日2014-08-15
公開日2015-01-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
4W88
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Crystal structure of XEG5A, a GH5 xyloglucan-specific endo-beta-1,4-glucanase from ruminal metagenomic library, in complex with a xyloglucan oligosaccharide and TRIS
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Xyloglucan-specific endo-beta-1,4-glucanase, ...
著者Santos, C.R, Cordeiro, R.L, Wong, D.W.S, Murakami, M.T.
登録日2014-08-22
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural Basis for Xyloglucan Specificity and alpha-d-Xylp(1 6)-d-Glcp Recognition at the -1 Subsite within the GH5 Family.
Biochemistry, 54, 2015
4WBT
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Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Shabalin, I.G, Bacal, P, Kowalska, A.K, Cooper, D.R, Stead, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-09-03
公開日2014-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
to be published
6R7Z
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CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form)
分子名称: Anoctamin-10
著者Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
登録日2019-03-29
公開日2019-05-01
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (5.14 Å)
主引用文献The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
4W8B
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BU of 4w8b by Molmil
Crystal structure of XEG5B, a GH5 xyloglucan-specific beta-1,4-glucanase from ruminal metagenomic library, in complex with XXLG
分子名称: Exo-xyloglucanase, GLYCEROL, SULFATE ION, ...
著者Santos, C.R, Cordeiro, R.L, Wong, D.W.S, Murakami, M.T.
登録日2014-08-22
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural Basis for Xyloglucan Specificity and alpha-d-Xylp(1 6)-d-Glcp Recognition at the -1 Subsite within the GH5 Family.
Biochemistry, 54, 2015
6RB9
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BU of 6rb9 by Molmil
The pore structure of Clostridium perfringens epsilon toxin
分子名称: Epsilon-toxin type B
著者Savva, C.G, Clark, A.R, Naylor, C.E, Popoff, M.R, Moss, D.S, Basak, A.K, Titball, R.W, Bokori-Brown, M.
登録日2019-04-09
公開日2019-06-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The pore structure of Clostridium perfringens epsilon toxin.
Nat Commun, 10, 2019
4WD7
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Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae by Zn-SAD phasing
分子名称: Bestrophin domain protein, ZINC ION
著者Yang, T, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-09-08
公開日2014-10-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and selectivity in bestrophin ion channels.
Science, 346, 2014
4UUG
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The (R)-selective amine transaminase from Aspergillus fumigatus with inhibitor bound
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, ...
著者Thomsen, M, Hinrichs, W.
登録日2014-07-28
公開日2014-11-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Biochemical Characterization of the Dual Substrate Recognition of the (R)-Selective Amine Transaminase from Aspergillus Fumigatus
FEBS J., 282, 2015
6RKO
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BU of 6rko by Molmil
Cryo-EM structure of the E. coli cytochrome bd-I oxidase at 2.68 A resolution
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome bd-I ubiquinol oxidase subunit 1, ...
著者Safarian, S, Hahn, A, Kuehlbrandt, W, Michel, H.
登録日2019-04-30
公開日2019-10-16
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Active site rearrangement and structural divergence in prokaryotic respiratory oxidases.
Science, 366, 2019
6RML
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Crystal structure of TOPBP1 BRCT0,1,2 in complex with a 53BP1 phosphopeptide
分子名称: 53BP1, DNA topoisomerase 2-binding protein 1
著者Day, M, Oliver, A.W, Pearl, L.H.
登録日2019-05-07
公開日2019-06-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.
Elife, 8, 2019
6KQV
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BU of 6kqv by Molmil
Solution Structure of the UbL Domain of USP19
分子名称: Ubiquitin carboxyl-terminal hydrolase 19
著者Xue, W, Hu, H.Y.
登録日2019-08-19
公開日2020-08-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
7YVR
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BU of 7yvr by Molmil
Crystal Structure of L-Threonine Aldolase from Neptunomonas marina
分子名称: GLYCEROL, L-threonine aldolase
著者He, Y.Z, Wang, J, Yan, W.P, Zhang, Y, Feng, Y.
登録日2022-08-19
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery and Engineering of the L-Threonine Aldolase from Neptunomonas marine for the Efficient Synthesis of beta-Hydroxy-alpha-amino Acids via C-C Formation
Acs Catalysis, 2023
4URG
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BU of 4urg by Molmil
Crystal Structure of GGDEF domain from T.maritima (active-like dimer)
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE
著者Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J.
登録日2014-06-30
公開日2014-10-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
6RV7
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Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid UXXR
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-Xylitol, ...
著者Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S.
登録日2019-05-31
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The structural basis of fungal glucuronoyl esterase activity on natural substrates.
Nat Commun, 11, 2020
6LOM
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Structure of CLHM1 from Caenorhabditis Elegans
分子名称: Calcium homeostasis modulator protein
著者Yang, W.X, Wang, Y.W, Zhang, X.C.
登録日2020-01-06
公開日2020-07-29
最終更新日2020-08-05
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Cryo-electron microscopy structure of CLHM1 ion channel from Caenorhabditis elegans.
Protein Sci., 29, 2020
7YTH
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Structure of OCPx1 from Nostoc flagelliforme CCNUN1
分子名称: Ketosteroid isomerase-related protein
著者Yang, Y.W, Liu, K, Chen, S.Z, Chen, M, Qiu, B.S.
登録日2022-08-14
公開日2023-06-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Functional specialization of expanded orange carotenoid protein paralogs in subaerial Nostoc species.
Plant Physiol., 192, 2023
7YRY
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F1-ATPase of Acinetobacter baumannii
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Saw, W.-G, Grueber, G.
登録日2022-08-11
公開日2023-06-21
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Atomic insights of an up and down conformation of the Acinetobacter baumannii F 1 -ATPase subunit epsilon and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis.
Faseb J., 37, 2023
6RZU
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BU of 6rzu by Molmil
Structure of s-Mgm1 decorating the outer surface of tubulated lipid membranes in the GTPgammaS bound state
分子名称: Putative mitochondrial dynamin protein
著者Faelber, K, Dietrich, L, Noel, J.K, Sanchez, R, Kudryashev, M, Kuelbrandt, W, Daumke, O.
登録日2019-06-13
公開日2019-07-24
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (14.7 Å)
主引用文献Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Nature, 571, 2019
6RV9
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Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid XUXXR
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-Xylitol, ...
著者Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S.
登録日2019-05-31
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The structural basis of fungal glucuronoyl esterase activity on natural substrates.
Nat Commun, 11, 2020

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