6R39
T. brucei FPPS in complex with 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid
Summary for 6R39
Entry DOI | 10.2210/pdb6r39/pdb |
Descriptor | Farnesyl pyrophosphate synthase, 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid (3 entities in total) |
Functional Keywords | sterol biosynthesis, farnesyl diphosphate synthase, trypanosoma brucei, homodimer, transferase |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 1 |
Total formula weight | 42438.46 |
Authors | Muenzker, L.,Petrick, J.K.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-19, release date: 2020-04-08, Last modification date: 2024-02-07) |
Primary citation | Petrick, J.K.,Jahnke, W. Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019 Cited by DOI: 10.17192/z2019.0501PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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