6R39

T. brucei FPPS in complex with 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid

Summary for 6R39

• Entry DOI: 10.2210/pdb6r39/pdb
• Descriptor: Farnesyl pyrophosphate synthase, 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid (3 entities in total)
• Functional Keywords: sterol biosynthesis, farnesyl diphosphate synthase, trypanosoma brucei, homodimer, transferase
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 1
• Total formula weight: 42438.46

Authors

Muenzker, L.,Petrick, J.K.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-19, release date: 2020-04-08, Last modification date: 2024-02-07)

• Primary citation: Petrick, J.K.,Jahnke, W.; Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery; Thesis, 2019; DOI: 10.17192/z2019.0501

Experimental method

X-RAY DIFFRACTION (2.6 Å)