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PDB: 34568 件

6EF5
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14-3-3 with peptide
分子名称: 14-3-3 protein zeta/delta, ARG-SER-LEU-SEP-ALA-PRO-GLY, LYS-LEU-SEP-LEU-GLN
著者Dhagat, U, Langendorf, C.G, Parker, M.W.P, Oakhill, J.S, Scott, J.W.
登録日2018-08-16
公開日2019-10-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献14-3-3 with peptide
To Be Published
3N86
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Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 4
分子名称: (1R,5R)-1,5-dihydroxy-4-oxo-3-[3-oxo-3-(phenylamino)propyl]cyclohex-2-ene-1-carboxylic acid, 3-dehydroquinate dehydratase
著者Dias, M.V.B, Snee, W.C, Bromfield, K.M, Payne, R, Palaninathan, S.K, Ciulli, A, Howard, N.I, Abell, C, Sacchettini, J.C, Blundell, T.L.
登録日2010-05-27
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis.
Biochem.J., 436, 2011
1INX
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A SIALIC ACID DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES
分子名称: (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者White, C.L, Janakiraman, M.N, Laver, W.G, Philippon, C, Vasella, A, Air, G.M, Luo, M.
登録日1994-09-26
公開日1995-02-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies.
J.Mol.Biol., 245, 1995
1IRK
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CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HUMAN INSULIN RECEPTOR
分子名称: ETHYL MERCURY ION, INSULIN RECEPTOR TYROSINE KINASE DOMAIN
著者Hubbard, S.R, Wei, L, Ellis, L, Hendrickson, W.A.
登録日1995-01-02
公開日1995-02-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the tyrosine kinase domain of the human insulin receptor.
Nature, 372, 1994
8PDI
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The phosphatase and C2 domains of SHIP1 with covalent Z1763271112
分子名称: (5-phenyl-1,3,4-thiadiazol-2-yl)methanimine, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
著者Bradshaw, W.J, Moreira, T, Pascoa, T.C, Bountra, C, Chalk, R, von Delft, F, Brennan, P.E, Gileadi, O.
登録日2023-06-12
公開日2023-07-26
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.
Structure, 32, 2024
5OQK
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Solution NMR structure of truncated, human Hv1/VSOP (Voltage-gated proton channel)
分子名称: Voltage-gated hydrogen channel 1
著者Bayrhuber, M, Maslennikov, I, Kwiatowski, W, Sobol, A, Wierschem, C, Eichmann, C, Riek, R.
登録日2017-08-12
公開日2019-04-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Solution Structure and Functional Behavior of the Human Proton Channel.
Biochemistry, 58, 2019
5HTJ
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Putative sugar kinases from Synechococcus elongatus PCC7942-D8A
分子名称: Probable sugar kinase
著者Xie, Y, Li, M, Chang, W.
登録日2016-01-26
公開日2016-06-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal Structures of Putative Sugar Kinases from Synechococcus Elongatus PCC 7942 and Arabidopsis Thaliana
Plos One, 11, 2016
7DTY
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Structural basis of ligand selectivity conferred by the human glucose-dependent insulinotropic polypeptide receptor
分子名称: CHOLESTEROL, Gastric inhibitory polypeptide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, F.H, Zhang, C, Zhou, Q.T, Hang, K.N, Zou, X.Y, Chen, Y, Wu, F, Rao, Q.D, Dai, A.T, Yin, W.C, Shen, D.D, Zhang, Y, Xia, T, Stevens, R.C, Xu, H.E, Yang, D.H, Zhao, L.H, Wang, M.W.
登録日2021-01-06
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor.
Elife, 10, 2021
4P9F
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E. coli McbR/YncC
分子名称: HTH-type transcriptional regulator mcbR
著者Lord, D.M, Page, R, Peti, W.
登録日2014-04-03
公開日2015-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献McbR/YncC: Implications for the Mechanism of Ligand and DNA Binding by a Bacterial GntR Transcriptional Regulator Involved in Biofilm Formation.
Biochemistry, 53, 2014
4LA5
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Crystal structure of 2-methylisoborneol synthase from Streptomyces coelicolor A3(2)
分子名称: 2-methylisoborneol synthase
著者Koksal, M, Christianson, D.W.
登録日2013-06-19
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Unexpected reactivity of 2-fluorolinalyl diphosphate in the active site of crystalline 2-methylisoborneol synthase.
Biochemistry, 52, 2013
5HV7
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Putative sugar kinases from Synechococcus elongatus PCC7942 in complex with D-ribulose
分子名称: D-ribulose, Probable sugar kinase
著者Xie, Y, Li, M, Chang, W.
登録日2016-01-28
公開日2016-06-08
最終更新日2020-07-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of Putative Sugar Kinases from Synechococcus Elongatus PCC 7942 and Arabidopsis Thaliana
Plos One, 11, 2016
4P6W
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Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain
分子名称: Glucocorticoid receptor, MOMETASONE FUROATE, Nuclear receptor coactivator 2
著者He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E.
登録日2014-03-25
公開日2014-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Structures and mechanism for the design of highly potent glucocorticoids.
Cell Res., 24, 2014
4LBB
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Crystal structure of human alpha-defensin 1 (HNP1) I20A mutant
分子名称: CHLORIDE ION, Neutrophil defensin 1
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2013-06-20
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.719 Å)
主引用文献Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function.
Plos One, 8, 2013
1INN
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CRYSTAL STRUCTURE OF D. RADIODURANS LUXS, P21
分子名称: AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, METHIONINE, ZINC ION
著者Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G.
登録日2001-05-14
公開日2001-06-08
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs.
Structure, 9, 2001
5HOP
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1.65 Angstrom resolution crystal structure of lmo0182 (residues 1-245) from Listeria monocytogenes EGD-e
分子名称: ACETATE ION, Lmo0182 protein
著者Halavaty, A.S, Light, S.H, Minasov, G, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-01-19
公開日2017-02-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity.
Structure, 25, 2017
4PDK
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FadR, Fatty Acid Responsive Transcription Factor from Vibrio cholerae, in Complex with oleoyl-CoA
分子名称: Fatty acid metabolism regulator protein, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)
著者Shi, W, Kull, F.J.
登録日2014-04-19
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand.
Nat Commun, 6, 2015
5HTX
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Putative sugar kinases from Arabidopsis thaliana in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Putative xylulose kinase
著者Xie, Y, Li, M, Chang, W.
登録日2016-01-27
公開日2016-06-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.492 Å)
主引用文献Crystal Structures of Putative Sugar Kinases from Synechococcus Elongatus PCC 7942 and Arabidopsis Thaliana
Plos One, 11, 2016
5HSF
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1.52 Angstrom Crystal Structure of Fc fragment of Human IgG1.
分子名称: Ig gamma-1 chain C region, TRIETHYLENE GLYCOL
著者Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Flores, K, Bishop, B, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-01-25
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献1.52 Angstrom Crystal Structure of Fc fragment of Human IgG1.
To Be Published
8HP0
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Crystal structure of meso-diaminopimelate dehydrogenase from Prevotella timonensis
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Meso-diaminopimelate D-dehydrogenase, SULFATE ION
著者Tan, Y, Song, W.
登録日2022-12-11
公開日2023-12-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Rational Design of Meso -Diaminopimelate Dehydrogenase with Enhanced Reductive Amination Activity for Efficient Production of d- p -Hydroxyphenylglycine.
Appl.Environ.Microbiol., 89, 2023
3N9T
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Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4
分子名称: 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, CITRATE ANION, FE (III) ION, ...
著者Liu, W, Shen, W, Fang, P, Li, J, Cui, Z.
登録日2010-05-31
公開日2010-08-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4
To be Published
5HVW
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Monomeric IgG4 Fc
分子名称: GLYCEROL, Ig gamma-4 chain C region, ZINC ION, ...
著者Oganesyan, V.Y, Shan, L, Dall'Acqua, W.F.
登録日2016-01-28
公開日2016-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Generation and Characterization of an IgG4 Monomeric Fc Platform.
Plos One, 11, 2016
5HVI
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Crystal structure of TEM1 beta-lactamase
分子名称: Beta-lactamase TEM
著者Roose, B.W, Dmochowski, I.J.
登録日2016-01-28
公開日2017-06-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献A Structural Basis for129Xe Hyper-CEST Signal in TEM-1 beta-Lactamase.
Chemphyschem, 2018
5HW1
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Crystal structure of TEM1 beta-lactamase in the presence of 1.2 MPa xenon
分子名称: Beta-lactamase TEM, XENON
著者Roose, B.W, Dmochowski, I.J.
登録日2016-01-28
公開日2017-06-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Structural Basis for129Xe Hyper-CEST Signal in TEM-1 beta-Lactamase.
Chemphyschem, 2018
8HRZ
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Crystal structure of the p97-N/D1 hexamer in complex with six p47-UBX domains
分子名称: ADENOSINE-5'-DIPHOSPHATE, NSFL1 cofactor p47, Transitional endoplasmic reticulum ATPase
著者Nguyen, T.Q, Kang, W.
登録日2022-12-16
公開日2023-12-20
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the p97-N/D1 hexmaer in complex with six p47-UBX domains
J. Korean Chem. Soc., 68, 2024
8HRU
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Cryo-EM structure of ACE2
分子名称: Angiotensin-converting enzyme 2
著者Xu, J, Liu, N, Wang, H.W.
登録日2022-12-16
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of ACE2
To Be Published

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件を2024-08-21に公開中

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