3COX
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![BU of 3cox by Molmil](/molmil-images/mine/3cox) | CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES | Descriptor: | CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Vrielink, A, Li, J, Brick, P, Blow, D.M. | Deposit date: | 1993-06-14 | Release date: | 1993-10-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases. Biochemistry, 32, 1993
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4KAY
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![BU of 4kay by Molmil](/molmil-images/mine/4kay) | |
4HST
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![BU of 4hst by Molmil](/molmil-images/mine/4hst) | Crystal structure of a double mutant of a class III engineered cephalosporin acylase | Descriptor: | 5,5-dihydroxy-L-norvaline, glutaryl-7-aminocephalosporanic acid acylase alpha chain, glutaryl-7-aminocephalosporanic acid acylase beta chain | Authors: | Vrielink, A, Golden, E, Patterson, R, Tie, W.J, Anandan, A, Flematti, G, Molla, G, Rosini, E, Pollegioni, L. | Deposit date: | 2012-10-30 | Release date: | 2013-02-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.571 Å) | Cite: | Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity. Biochem.J., 451, 2013
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4HSR
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![BU of 4hsr by Molmil](/molmil-images/mine/4hsr) | Crystal Structure of a class III engineered cephalosporin acylase | Descriptor: | 5,5-dihydroxy-L-norvaline, glutaryl-7-aminocephalosporanic acid acylase alpha chain, glutaryl-7-aminocephalosporanic acid acylase beta chain | Authors: | Vrielink, A, Golden, E, Patterson, R, Tie, W.J, Anandan, A, Flematti, G, Molla, G, Rosini, E, Pollegioni, L. | Deposit date: | 2012-10-30 | Release date: | 2013-02-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity. Biochem.J., 451, 2013
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4KAV
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![BU of 4kav by Molmil](/molmil-images/mine/4kav) | |
2I0K
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![BU of 2i0k by Molmil](/molmil-images/mine/2i0k) | |
2BGU
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![BU of 2bgu by Molmil](/molmil-images/mine/2bgu) | CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE | Descriptor: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | Authors: | Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S. | Deposit date: | 1994-06-09 | Release date: | 1995-12-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose. EMBO J., 13, 1994
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1IJH
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![BU of 1ijh by Molmil](/molmil-images/mine/1ijh) | CHOLESTEROL OXIDASE FROM STREPTOMYCES ASN485LEU MUTANT | Descriptor: | CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Vrielink, A, Lario, P.I. | Deposit date: | 2001-04-26 | Release date: | 2001-12-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase. Biochemistry, 40, 2001
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2BGT
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1B4V
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![BU of 1b4v by Molmil](/molmil-images/mine/1b4v) | CHOLESTEROL OXIDASE FROM STREPTOMYCES | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE) | Authors: | Vrielink, A, Yue, Q.K. | Deposit date: | 1998-12-30 | Release date: | 1999-01-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants. Biochemistry, 38, 1999
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1B8S
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![BU of 1b8s by Molmil](/molmil-images/mine/1b8s) | CHOLESTEROL OXIDASE FROM STREPTOMYCES GLU361GLN MUTANT | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE) | Authors: | Vrielink, A, Yue, Q.K. | Deposit date: | 1999-02-02 | Release date: | 1999-02-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants. Biochemistry, 38, 1999
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1CC2
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![BU of 1cc2 by Molmil](/molmil-images/mine/1cc2) | CHOLESTEROL OXIDASE FROM STREPTOMYCES HIS447GLN MUTANT | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE) | Authors: | Vrielink, A, Yue, Q.K. | Deposit date: | 1999-03-03 | Release date: | 1999-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants. Biochemistry, 38, 1999
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1CBO
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![BU of 1cbo by Molmil](/molmil-images/mine/1cbo) | CHOLESTEROL OXIDASE FROM STREPTOMYCES HIS447ASN MUTANT | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE) | Authors: | Vrielink, A, Yue, Q.K. | Deposit date: | 1999-02-26 | Release date: | 1999-03-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants. Biochemistry, 38, 1999
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7JRB
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![BU of 7jrb by Molmil](/molmil-images/mine/7jrb) | Phospholipase D engineered mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Phospholipase D | Authors: | Vrielink, A, Samantha, A. | Deposit date: | 2020-08-12 | Release date: | 2021-04-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.493 Å) | Cite: | Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
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7JRW
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![BU of 7jrw by Molmil](/molmil-images/mine/7jrw) | Phospholipase D engineered mutant bound to phosphatidic acid (5 day soak) | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dibutanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Vrielink, A, Samantha, A. | Deposit date: | 2020-08-13 | Release date: | 2021-04-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
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7JRV
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![BU of 7jrv by Molmil](/molmil-images/mine/7jrv) | Phospholipase D engineered mutant bound to phosphatidic acid (30 minute soak) | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dibutanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Vrielink, A, Samantha, A. | Deposit date: | 2020-08-13 | Release date: | 2021-04-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
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7JS5
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![BU of 7js5 by Molmil](/molmil-images/mine/7js5) | |
7JS7
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![BU of 7js7 by Molmil](/molmil-images/mine/7js7) | |
7JRU
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![BU of 7jru by Molmil](/molmil-images/mine/7jru) | Phospholipase D engineered mutant bound to phosphatidic acid (8 hour soak) | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dibutanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Vrielink, A, Samantha, A. | Deposit date: | 2020-08-13 | Release date: | 2021-04-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
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7JRC
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![BU of 7jrc by Molmil](/molmil-images/mine/7jrc) | Phospholipase D engineered mutant in complex with phosphate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, PHOSPHATE ION, ... | Authors: | Vrielink, A, Samantha, A. | Deposit date: | 2020-08-12 | Release date: | 2021-04-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
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1MXT
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![BU of 1mxt by Molmil](/molmil-images/mine/1mxt) | Atomic resolution structure of Cholesterol oxidase (Streptomyces sp. SA-COO) | Descriptor: | CHOLESTEROL OXIDASE, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, ... | Authors: | Vrielink, A, Lario, P.I. | Deposit date: | 2002-10-03 | Release date: | 2003-02-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Sub-atomic resolution crystal structure of cholesterol oxidase:
What atomic resolution crystallography reveals about enzyme mechanism and the role of FAD cofactor in redox activity J.Mol.Biol., 326, 2003
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1BGU
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![BU of 1bgu by Molmil](/molmil-images/mine/1bgu) | CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE | Descriptor: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | Authors: | Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S. | Deposit date: | 1994-06-09 | Release date: | 1994-10-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose. EMBO J., 13, 1994
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1BGT
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1N4V
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1N1P
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![BU of 1n1p by Molmil](/molmil-images/mine/1n1p) | |