PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Crystal Structure of the A287F Active Site Mutant of TS-DHFR from Cryptosporidium hominis
Descriptor:	10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DIHYDROFOLIC ACID, ...
Authors:	Vargo, M.A, Martucci, W.E, Anderson, K.S.
Deposit date:	2008-06-26
Release date:	2008-08-19
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.74 Å)
Cite:	Explaining an unusually fast parasitic enzyme: folate tail-binding residues dictate substrate positioning and catalysis in Cryptosporidium hominis thymidylate synthase. Biochemistry, 47, 2008

Crystal Structure of the S290G Active Site Mutant of TS-DHFR from Cryptosporidium hominis
Descriptor:	10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Chain A, ...
Authors:	Martucci, W.E, Vargo, M.A.
Deposit date:	2007-01-11
Release date:	2007-07-17
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis Biochemistry, 46, 2007

Crystal Structure of the A287F/S290G Active Site Mutant of TS-DHFR from Cryptosporidium hominis
Descriptor:	10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DIHYDROFOLIC ACID, ...
Authors:	Martucci, W.E, Vargo, M.A, Anderson, K.S.
Deposit date:	2008-06-26
Release date:	2008-08-19
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (3.25 Å)
Cite:	Explaining an unusually fast parasitic enzyme: folate tail-binding residues dictate substrate positioning and catalysis in Cryptosporidium hominis thymidylate synthase. Biochemistry, 47, 2008