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PDB: 109 件

2KDQ
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Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimic of Tat protein
分子名称: HIV-1 TAR RNA, L-22 CYCLIC PEPTIDE
著者Davidson, A, Leeper, T.C, Varani, G.
登録日2009-01-14
公開日2009-06-23
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein
Proc.Natl.Acad.Sci.USA, 106, 2009
2KHP
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Solution structure of Glutaredoxin from Brucella melitensis
分子名称: GLUTAREDOXIN
著者Zheng, S, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-04-10
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens.
Acta Crystallogr.,Sect.F, 67, 2011
2KM8
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Interdomain RRM packing contributes to RNA recognition in the rna15, hrp1, anchor RNA 3' processing ternary complex
分子名称: 5'-R(P*UP*AP*UP*AP*UP*AP*UP*AP*AP*UP*AP*AP*U)-3', Nuclear polyadenylated RNA-binding protein 4, mRNA 3'-end-processing protein RNA15
著者Leeper, T.C, Varani, G.
登録日2009-07-24
公開日2010-07-28
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Novel Protein-Protein Contacts Facilitate mRNA 3'-Processing Signal Recognition by Rna15 and Hrp1.
J.Mol.Biol., 401, 2010
2KGP
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Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone)
分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, RNA (25-MER)
著者Zheng, S, Chen, Y, Donahue, C.P, Wolfe, M.S, Varani, G.
登録日2009-03-13
公開日2009-06-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone).
Chem.Biol., 16, 2009
2KWL
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Solution Structure of acyl carrier protein from Borrelia burgdorferi
分子名称: Acyl carrier protein
著者Barnwal, R, Vittal, V, Moody, J, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-04-12
公開日2010-04-28
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of an acyl-carrier protein from Borrelia burgdorferi.
Acta Crystallogr.,Sect.F, 67, 2011
2KO7
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Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with Cycloheximide-N-ethylethanoate
分子名称: Peptidyl-prolyl cis-trans isomerase, ethyl (4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-dioxopiperidin-1-yl)acetate
著者Zheng, S, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-09-11
公開日2009-09-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
Biochem.J., 437, 2011
2KX5
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Recognition of HIV TAR RNA by peptide mimetic of Tat protein
分子名称: Cyclic peptide mimetic of Tat protein, HIV TAR RNA
著者Davidson, A, Patora-Komisarska, K, Robinson, J, Varani, G.
登録日2010-04-26
公開日2010-07-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein.
Nucleic Acids Res., 39, 2011
2KLX
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Solution structure of glutaredoxin from Bartonella henselae str. Houston
分子名称: Glutaredoxin
著者Leeper, T.C, Varani, G, Zheng, S, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-07-10
公開日2009-07-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens.
Acta Crystallogr.,Sect.F, 67, 2011
2L2S
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Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine
分子名称: 1-{[(4-methylphenyl)sulfanyl]acetyl}piperidine, Peptidyl-prolyl cis-trans isomerase
著者Zheng, S, Barnwal, R, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-27
公開日2010-09-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine
To be Published
2L8H
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Chemical probe bound to HIV TAR RNA
分子名称: 4-methoxynaphthalen-2-amine, ARGININE, HIV TAR RNA
著者Davidson, A, Begley, D, Lau, C, Varani, G.
登録日2011-01-12
公開日2011-03-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Small-Molecule Probe Induces a Conformation in HIV TAR RNA Capable of Binding Drug-Like Fragments.
J.Mol.Biol., 410, 2011
2L2Q
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Solution Structure of cellobiose-specific phosphotransferase IIB component protein from Borrelia burgdorferi
分子名称: PTS system, cellobiose-specific IIB component (CelA)
著者Yang, F, Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-25
公開日2010-09-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of cellobiose-specific phosphotransferase IIB component protein from Borrelia burgdorferi
To be Published
2L0I
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Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide
分子名称: DNA-directed RNA polymerase, Regulator of Ty1 transposition protein 103
著者Lunde, B.M, Reichow, S.L, Kim, M, Suh, H, Leeper, T.C, Yang, F, Mutschler, H, Buratowski, S, Meinhart, A, Varani, G.
登録日2010-07-06
公開日2010-09-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
2LBB
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Solution structure of acyl CoA binding protein from Babesia bovis T2Bo
分子名称: Acyl CoA binding protein
著者Yang, F, Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-03-29
公開日2011-04-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of acyl CoA binding protein from Babesia bovis T2Bo
To be Published
2LHJ
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NMR structure of the high mobility group protein-like protein NHP1 from Babesia bovis T2Bo (BaboA.00841.a)
分子名称: High mobility group protein homolog NHP1
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-08-11
公開日2011-08-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H and 15N Assigned Chemical Shifts for high mobility group protein-like protein NHP1 from Babesia bovis
To be Published
2LOL
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NMR structure of an acyl-carrier protein from Rickettsia prowazekii, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
分子名称: Acyl carrier protein
著者Barnwal, R, Gonen, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-01-25
公開日2012-02-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of an acyl-carrier protein from Rickettsia prowazekii, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
To be Published
2LJU
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Solution structure of putative oxidoreductase from Ehrlichia chaffeensis, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
分子名称: Putative oxidoreductase
著者Yang, F, Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-09-29
公開日2011-10-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of putative oxidoreductase from Ehrlichia chaffeensis
To be Published
2LWK
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Solution structure of small molecule-influenza RNA complex
分子名称: 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine, RNA (32-MER)
著者Lee, M.-K, Varani, G, Choi, B.-S, Pellecchia, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-08-01
公開日2012-08-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication.
Chem.Commun.(Camb.), 50, 2014
2MJ3
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BU of 2mj3 by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments and structure of Iron-sulfur cluster binding protein from Ehrlichia chaffeensis
分子名称: Iron-sulfur cluster binding protein
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-12-23
公開日2014-01-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Backbone 1H, 13C, and 15N Chemical Shift Assignments and structure of Iron-sulfur cluster binding protein from Ehrlichia chaffeensis
To be Published
2MCQ
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NMR structure of a BolA-like hypothetical protein RP812 from Rickettsia prowazekii, Seattle structural genomics center for infectious disease (SSGCID)
分子名称: Uncharacterized protein RP812
著者Chen, Y, Barnwal, R, Yang, F, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-08-22
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of a BolA-like hypothetical protein RP812 from Rickettsia prowazekii, Seattle structural genomics center for infectious disease (SSGCID)
To be Published
2M4Y
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Rubredoxin type protein from Mycobacterium ulcerans
分子名称: Rubredoxin
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-02-11
公開日2013-03-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of Rubredoxin type protein from Mycobacterium ulcerans
To be Published
2N6T
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NMR Assignment and NMR Structure of CssA3 (top stem) of CssA thermometer
分子名称: RNA (42-MER)
著者Barnwal, R, Godin, K, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-08-28
公開日2016-08-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis.
Nucleic Acids Res., 44, 2016
2MRL
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Backbone 1H, 13C, and 15N Chemical Shift Assignments and NMR structure for potential drug target from Burkholderia thailandensis E264
分子名称: Uncharacterized protein BTH I2711
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-07-09
公開日2014-07-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure for potential drug target from Burkholderia thailandensis E264
To be Published
2NAX
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Structure of CCHC zinc finger domain of Pcf11
分子名称: Protein PCF11, ZINC ION
著者Yang, F, Varani, G.
登録日2016-01-12
公開日2016-11-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The C terminus of Pcf11 forms a novel zinc-finger structure that plays an essential role in mRNA 3'-end processing.
RNA, 23, 2017
2N82
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solution structure of the complex of microRNA 20b pre-element with Rbfox RRM
分子名称: RNA (5'-R(*GP*GP*UP*AP*GP*UP*UP*UP*UP*GP*GP*CP*AP*UP*GP*AP*CP*UP*CP*UP*AP*CP*C)-3'), RNA binding protein fox-1 homolog 1
著者Yang, F, Chen, Y, Varani, G.
登録日2015-09-30
公開日2016-04-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer.
Nucleic Acids Res., 44, 2016
2N6X
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NMR Assignment and structure of CssA5 (middle region) of CssA thermometer from Neisseria meningitidis
分子名称: RNA (43-MER)
著者Barnwal, R, Godin, K, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-08-31
公開日2016-08-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis.
Nucleic Acids Res., 44, 2016

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