2A3J
| Structure of URNdesign, a complete computational redesign of human U1A protein | Descriptor: | U1 small nuclear ribonucleoprotein A | Authors: | Varani, G, Dobson, N, Dantas, G, Baker, D. | Deposit date: | 2005-06-24 | Release date: | 2006-06-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | High-Resolution Structural Validation of the Computational Redesign of Human U1A Protein Structure, 14, 2006
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1EI2
| STRUCTURAL BASIS FOR RECOGNITION OF THE RNA MAJOR GROOVE IN THE TAU EXON 10 SPLICING REGULATORY ELEMENT BY AMINOGLYCOSIDE ANTIBIOTICS | Descriptor: | NEOMYCIN, TAU EXON 10 SRE RNA | Authors: | Varani, L, Spillantini, M.G, Goedert, M, Varani, G. | Deposit date: | 2000-02-23 | Release date: | 2000-03-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics. Nucleic Acids Res., 28, 2000
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1QC8
| NMR STRUCTURE OF TAU EXON 10 SPLICING REGULATORY ELEMENT RNA | Descriptor: | TAU EXON 10 SPLICING REGULATORY ELEMENT RNA | Authors: | Varani, L, Spillantini, M.G, Klug, A, Goedert, M, Varani, G. | Deposit date: | 1999-05-18 | Release date: | 1999-08-31 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proc.Natl.Acad.Sci.USA, 96, 1999
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1DZ5
| The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein | Descriptor: | PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | Authors: | Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. | Deposit date: | 2000-02-16 | Release date: | 2000-03-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein Nat.Struct.Biol., 7, 2000
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2FEY
| The structure of stem loop IV of Tetrahymena telomerase RNA | Descriptor: | stem-loop IV of Tetrahymena telomerase RNA | Authors: | Chen, Y, Fender, J, Legassie, J.D, Jarstfer, M.B, Bryan, T.M, Varani, G. | Deposit date: | 2005-12-16 | Release date: | 2006-06-27 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of stem-loop IV of Tetrahymena telomerase RNA. Embo J., 25, 2006
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6U79
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7SHX
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6W3M
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1Z31
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6PK9
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7K4L
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2V3M
| Structure of the Gar1 domain of NAf1 | Descriptor: | NAF1, SULFATE ION | Authors: | Leulliot, N, Godin, K.S, Hoareau-Aveilla, C, Quevillon-Cheruel, S, Varani, G, Henry, Y, van Tilbeurgh, H. | Deposit date: | 2007-06-19 | Release date: | 2007-07-10 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | The Box H/Aca Rnp Assembly Factor Naf1P Contains a Domain Homologous to Gar1P Mediating its Interaction with Cbf5P. J.Mol.Biol., 371, 2007
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5JTK
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6DZC
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6DZA
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6DZE
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6MXQ
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4M3O
| Crystal structure of K.lactis Rtr1 NTD | Descriptor: | KLLA0F12672p, ZINC ION | Authors: | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | Deposit date: | 2013-08-06 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD. J.Mol.Biol., 426, 2014
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5T3Y
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6NOA
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1AUD
| U1A-UTRRNA, NMR, 31 STRUCTURES | Descriptor: | RNA 3UTR, U1A 102 | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | Deposit date: | 1997-08-22 | Release date: | 1998-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis of the RNA-binding specificity of human U1A protein. EMBO J., 16, 1997
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7UME
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7UMC
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7VRL
| Solution structure of Rbfox RRM bound to a non-cognate RNA | Descriptor: | RNA (5'-R(*UP*GP*CP*AP*UP*AP*U)-3'), RNA binding protein fox-1 homolog 1 | Authors: | Yang, F, Varani, G. | Deposit date: | 2021-10-23 | Release date: | 2022-10-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity. Nat Commun, 14, 2023
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7UMD
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