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PDB: 110 results

2A3J
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BU of 2a3j by Molmil
Structure of URNdesign, a complete computational redesign of human U1A protein
Descriptor: U1 small nuclear ribonucleoprotein A
Authors:Varani, G, Dobson, N, Dantas, G, Baker, D.
Deposit date:2005-06-24
Release date:2006-06-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:High-Resolution Structural Validation of the Computational Redesign of Human U1A Protein
Structure, 14, 2006
1EI2
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BU of 1ei2 by Molmil
STRUCTURAL BASIS FOR RECOGNITION OF THE RNA MAJOR GROOVE IN THE TAU EXON 10 SPLICING REGULATORY ELEMENT BY AMINOGLYCOSIDE ANTIBIOTICS
Descriptor: NEOMYCIN, TAU EXON 10 SRE RNA
Authors:Varani, L, Spillantini, M.G, Goedert, M, Varani, G.
Deposit date:2000-02-23
Release date:2000-03-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.
Nucleic Acids Res., 28, 2000
1QC8
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BU of 1qc8 by Molmil
NMR STRUCTURE OF TAU EXON 10 SPLICING REGULATORY ELEMENT RNA
Descriptor: TAU EXON 10 SPLICING REGULATORY ELEMENT RNA
Authors:Varani, L, Spillantini, M.G, Klug, A, Goedert, M, Varani, G.
Deposit date:1999-05-18
Release date:1999-08-31
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17.
Proc.Natl.Acad.Sci.USA, 96, 1999
1DZ5
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BU of 1dz5 by Molmil
The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein
Descriptor: PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
Authors:Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G.
Deposit date:2000-02-16
Release date:2000-03-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
2FEY
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BU of 2fey by Molmil
The structure of stem loop IV of Tetrahymena telomerase RNA
Descriptor: stem-loop IV of Tetrahymena telomerase RNA
Authors:Chen, Y, Fender, J, Legassie, J.D, Jarstfer, M.B, Bryan, T.M, Varani, G.
Deposit date:2005-12-16
Release date:2006-06-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of stem-loop IV of Tetrahymena telomerase RNA.
Embo J., 25, 2006
6U79
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BU of 6u79 by Molmil
Solution NMR structure of 5' UTR stem loop B from West Nile Virus
Descriptor: 5' UTR region stem loop
Authors:Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-09-01
Release date:2020-08-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
7SHX
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BU of 7shx by Molmil
A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript, NMR, minimized average structure
Descriptor: RNA (94-MER)
Authors:Sharma, S, Varani, G.
Deposit date:2021-10-11
Release date:2022-10-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript.
Nucleic Acids Res., 50, 2022
6W3M
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BU of 6w3m by Molmil
Solution NMR Structure of 5'UTR Stem Loop B in DENV4 Flavivirus.
Descriptor: RNA (41-MER)
Authors:Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-03-09
Release date:2020-09-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
1Z31
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BU of 1z31 by Molmil
The structure of an enzyme-activating fragment of human telomerase RNA
Descriptor: human telomerase PJ6 hairpin
Authors:Leeper, T.C, Varani, G.
Deposit date:2005-03-10
Release date:2005-03-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of an enzyme-activating fragment of human telomerase RNA.
RNA, 11, 2005
6PK9
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BU of 6pk9 by Molmil
Solution Structure of lncRNA (LINK-A) 20-nt Hexaloop Hairpin
Descriptor: RNA (5'-R(*GP*GP*AP*GP*GP*GP*UP*AP*GP*AP*CP*UP*CP*GP*CP*UP*CP*UP*CP*C)-3')
Authors:Amado, A.Y, Walker, M, Varani, G.
Deposit date:2019-06-28
Release date:2020-07-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the lncRNA LINK-A Hexaloop Hairpin in PI(3,4,5)P3 Interaction
To Be Published
7K4L
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BU of 7k4l by Molmil
DENV1 SLA bottom stem RNA (DenvBS)
Descriptor: DenvSLA RNA
Authors:Sun, Y.T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-15
Release date:2021-09-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of Denv1 5'UTR SLA region
To Be Published
2V3M
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BU of 2v3m by Molmil
Structure of the Gar1 domain of NAf1
Descriptor: NAF1, SULFATE ION
Authors:Leulliot, N, Godin, K.S, Hoareau-Aveilla, C, Quevillon-Cheruel, S, Varani, G, Henry, Y, van Tilbeurgh, H.
Deposit date:2007-06-19
Release date:2007-07-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:The Box H/Aca Rnp Assembly Factor Naf1P Contains a Domain Homologous to Gar1P Mediating its Interaction with Cbf5P.
J.Mol.Biol., 371, 2007
5JTK
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BU of 5jtk by Molmil
NMR structure of Uncharacterized protein from Pseudomonas aeruginosa PAO1
Descriptor: Uncharacterized protein
Authors:Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-05-09
Release date:2016-05-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure of Uncharacterized protein from Pseudomonas aeruginosa PAO1
To Be Published
6DZC
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BU of 6dzc by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox6
Descriptor: CPfox6
Authors:Sun, Y.-T, Varani, G.
Deposit date:2018-07-03
Release date:2019-05-15
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
6DZA
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BU of 6dza by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox4
Descriptor: CPfox4
Authors:Sun, Y.-T, Shortridge, M.D, Varani, G.
Deposit date:2018-07-03
Release date:2019-05-15
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
6DZE
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BU of 6dze by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox7
Descriptor: CPfox7
Authors:Sun, Y.-T, Varani, G.
Deposit date:2018-07-03
Release date:2019-05-15
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
6MXQ
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BU of 6mxq by Molmil
Solution structure of a c-JUN 5' UTR stem-loop associated with specialized cap-dependent translation initiation
Descriptor: RNA C-JUN TL
Authors:Walker, M, Shortridge, M, Varani, G.
Deposit date:2018-10-31
Release date:2020-05-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the RNA Specialized Translation Initiation Element that Recruits eIF3 to the 5'-UTR of c-Jun.
J.Mol.Biol., 432, 2020
4M3O
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BU of 4m3o by Molmil
Crystal structure of K.lactis Rtr1 NTD
Descriptor: KLLA0F12672p, ZINC ION
Authors:Hsu, P.L, Yang, W, Zheng, N, Varani, G.
Deposit date:2013-08-06
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD.
J.Mol.Biol., 426, 2014
5T3Y
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BU of 5t3y by Molmil
Solution structure of response regulator protein from Burkholderia multivorans
Descriptor: Two-component system response regulator
Authors:Yang, F, Lim, Y.-B, Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-08-26
Release date:2016-09-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of response regulator protein from Burkholderia multivorans
To Be Published
6NOA
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BU of 6noa by Molmil
Solution Structure of the RNA element that recruits eIF3 to the 5'-UTR of c-Jun and regulates specialized translation initiation (apical loop)
Descriptor: C-JUN SL1
Authors:Walker, M, Shortridge, M, Varani, G.
Deposit date:2019-01-16
Release date:2020-07-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the RNA Specialized Translation Initiation Element that Recruits eIF3 to the 5'-UTR of c-Jun.
J.Mol.Biol., 432, 2020
1AUD
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BU of 1aud by Molmil
U1A-UTRRNA, NMR, 31 STRUCTURES
Descriptor: RNA 3UTR, U1A 102
Authors:Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G.
Deposit date:1997-08-22
Release date:1998-02-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
7UME
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BU of 7ume by Molmil
DENV1 SLA top stemloop RNA (DenvTSL)
Descriptor: RNA (28-MER)
Authors:Sun, Y.T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-06
Release date:2022-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the dengue virus RNA promoter.
Rna, 28, 2022
7UMC
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BU of 7umc by Molmil
DENV1 SLA RNA (DenvSLATL)
Descriptor: RNA (70-MER)
Authors:Sun, Y.T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-06
Release date:2022-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the dengue virus RNA promoter.
Rna, 28, 2022
7VRL
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BU of 7vrl by Molmil
Solution structure of Rbfox RRM bound to a non-cognate RNA
Descriptor: RNA (5'-R(*UP*GP*CP*AP*UP*AP*U)-3'), RNA binding protein fox-1 homolog 1
Authors:Yang, F, Varani, G.
Deposit date:2021-10-23
Release date:2022-10-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity.
Nat Commun, 14, 2023
7UMD
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BU of 7umd by Molmil
DENV1 SLA three-way junction RNA (DenvSLAsh)
Descriptor: RNA (40-MER)
Authors:Sun, Y.T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-06
Release date:2022-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the dengue virus RNA promoter.
Rna, 28, 2022

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