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PDB: 24 件

2AP2
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SINGLE CHAIN FV OF C219 IN COMPLEX WITH SYNTHETIC EPITOPE PEPTIDE
分子名称: P-GLYCOPROTEIN, SINGLE CHAIN FV
著者Van Den Elsen, J.M.H, Rose, D.R.
登録日1999-03-22
公開日1999-11-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antibody C219 recognizes an alpha-helical epitope on P-glycoprotein.
Proc.Natl.Acad.Sci.USA, 96, 1999
1HTY
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GOLGI ALPHA-MANNOSIDASE II
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R.
登録日2001-01-02
公開日2002-01-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
1HXK
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GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH DEOXYMANNOJIRIMICIN
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1-DEOXYMANNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R.
登録日2001-01-16
公開日2002-01-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
7Z5L
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Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and dimethyl sulfoxide (DMSO)
分子名称: GLYCEROL, Insulin A chain, Insulin B chain, ...
著者van den Elsen, J.M.H, Wahid, A.A, Crennell, C.
登録日2022-03-09
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling
To Be Published
7Z5Q
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Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP)
分子名称: Insulin, Insulin A chain, SULFATE ION
著者van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J.
登録日2022-03-09
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling
To Be Published
1HZF
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C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A
分子名称: COMPLEMENT FACTOR C4A
著者van den Elsen, J.M.H, Martin, A, Wong, V, Clemenza, L, Rose, D.R, Isenman, D.E.
登録日2001-01-24
公開日2002-10-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray crystal structure of the C4d fragment of human complement component C4.
J.Mol.Biol., 322, 2002
1HWW
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GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SWAINSONINE
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R.
登録日2001-01-10
公開日2002-01-10
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
2MPA
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BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, CONJUGATE OF PORA P1.16 PEPTIDE WITH FLUORESCEIN, MN12H2 IGG2A-KAPPA, ...
著者Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P.
登録日1999-06-09
公開日1999-06-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
1MNU
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UNLIGANDED BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (HEAVY CHAIN)), PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (LIGHT CHAIN))
著者Van Den Elsen, J, Vandeputte-Rutten, L, Kroon, J, Gros, P.
登録日1999-04-30
公開日1999-05-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Bactericidal antibody recognition of meningococcal PorA by induced fit. Comparison of liganded and unliganded Fab structures.
J.Biol.Chem., 274, 1999
1MPA
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BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, MN12H2 IGG2A-KAPPA, PORA P1.16 PEPTIDE FLUORESCEIN CONJUGATE
著者Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P.
登録日1997-02-26
公開日1997-09-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
1QUB
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CRYSTAL STRUCTURE OF THE GLYCOSYLATED FIVE-DOMAIN HUMAN BETA2-GLYCOPROTEIN I PURIFIED FROM BLOOD PLASMA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (human beta2-Glycoprotein I), ...
著者Bouma, B, de Groot, P.G, van den Elsen, J.M.H, Ravelli, R.B.G, Schouten, A, Simmelink, M.J.A, Derksen, R.H.W.M, Kroon, J, Gros, P.
登録日1999-07-01
公開日1999-10-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.
EMBO J., 18, 1999
7AD6
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Crystal structure of human complement C5 in complex with the K92 bovine knob domain peptide.
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYSTEINE, ...
著者Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R.
登録日2020-09-14
公開日2021-03-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
7AD7
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Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R.
登録日2020-09-14
公開日2021-03-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
6RMT
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Crystal structure of disulphide-linked human C3d dimer
分子名称: CHLORIDE ION, Complement C3
著者Wahid, A.A, van den Elsen, J.M.H, Crennell, S.J.
登録日2019-05-07
公開日2020-11-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights Into the Structure-Function Relationships of Dimeric C3d Fragments.
Front Immunol, 12, 2021
6RMU
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Crystal structure of disulphide-linked human C3d dimer in complex with Staphylococcus aureus complement subversion protein Sbi-IV
分子名称: 1,2-ETHANEDIOL, Complement C3, DI(HYDROXYETHYL)ETHER, ...
著者Wahid, A.A, van den Elsen, J.M.H, Crennell, S.J.
登録日2019-05-07
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Staphylococcal Complement Evasion Protein Sbi Stabilises C3d Dimers by Inducing an N-Terminal Helix Swap
Front Immunol, 13, 2022
4OFS
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Crystal structure of a truncated catalytic core of the 2-oxoacid dehydrogenase multienzyme complex from Thermoplasma acidophilum
分子名称: Probable lipoamide acyltransferase
著者Marrot, N.L, Marshall, J.J.T, Svergun, D.I, Crennell, S.J, Hough, D.W, van den Elsen, J.M.H, Danson, M.J.
登録日2014-01-15
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.
Biochem.J., 463, 2014
2JVG
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Structure of C3-binding domain 4 of Staphylococcus aureus protein Sbi
分子名称: IgG-binding protein SBI
著者Upadhyay, A, Burman, J, Clark, E.A, van den Elsen, J.M.H, Bagby, S.
登録日2007-09-20
公開日2008-06-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi.
J.Biol.Chem., 283, 2008
2JVH
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Structure of C3-binding domain 4 of S. aureus protein Sbi
分子名称: IgG-binding protein SBI
著者Upadhyay, A, Burman, J, Clark, E.A, van den Elsen, J.M.H, Bagby, S.
登録日2007-09-20
公開日2008-06-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi.
J.Biol.Chem., 283, 2008
2JOL
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Average NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei
分子名称: Putative G-nucleotide exchange factor
著者Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S.
登録日2007-03-14
公開日2007-03-27
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
Biochem.J., 411, 2008
2JOK
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NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei
分子名称: Putative G-nucleotide exchange factor
著者Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S.
登録日2007-03-14
公開日2007-09-18
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
Biochem.J., 411, 2008
2WY8
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Staphylococcus aureus complement subversion protein Sbi-IV in complex with complement fragment C3d
分子名称: COMPLEMENT C3D FRAGMENT, GLYCEROL, IGG-BINDING PROTEIN
著者Clark, E.A, Crennell, S, Upadhyay, A, Mackay, J.D, Bagby, S, van den Elsen, J.M.
登録日2009-11-13
公開日2010-12-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011
3RQC
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Crystal structure of the catalytic core of the 2-oxoacid dehydrogenase multienzyme complex from Thermoplasma acidophilum
分子名称: Probable lipoamide acyltransferase
著者Marrott, N.L, Crennell, S.J, Hough, D.W, Danson, M.J, van den Elsen, J.M.H.
登録日2011-04-28
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly.
Febs J., 279, 2012
3OED
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The structure of the complex between complement receptor CR2 and its ligand complement fragment C3d
分子名称: Complement C3, Complement receptor type 2
著者Isenman, D.E, van den Elsen, J.M.H.
登録日2010-08-12
公開日2011-05-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献A crystal structure of the complex between human complement receptor 2 and its ligand C3d.
Science, 332, 2011
2WY7
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Staphylococcus aureus complement subversion protein Sbi-IV in complex with complement fragment C3d revealing an alternative binding mode
分子名称: COMPLEMENT C3D FRAGMENT, GLYCEROL, IGG-BINDING PROTEIN
著者Clark, E.A, Crennell, S, Upadhyay, A, Mackay, J.D, Bagby, S, van den Elsen, J.M.
登録日2009-11-13
公開日2010-12-01
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011

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