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PDB: 4 results
7RCF
Fourth stage reengineered variant of I-OnuI with stability enhancing substitutions
Descriptor:
1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:
Ubilla-Rodriguez, N.C
,
Werther, R.A
,
Stoddard, B.L.
Deposit date:
2021-07-07
Release date:
2022-06-29
Last modified:
2023-10-18
Method:
X-RAY DIFFRACTION (2.233 Å)
Cite:
Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7RCD
Second stage reengineered variant of I-OnuI targeting human PD1 gene with activity enhancing substitutions
Descriptor:
CALCIUM ION, DNA (26-MER), I-OnuI_e-hPD1-c
Authors:
Ubilla-Rodriguez, N.C
,
Werther, R.A
,
Stoddard, B.L.
Deposit date:
2021-07-07
Release date:
2022-06-29
Last modified:
2023-10-18
Method:
X-RAY DIFFRACTION (2.448 Å)
Cite:
Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7RCE
Third stage reengineered variant of I-OnuI with specificity enhancing substitutions
Descriptor:
CALCIUM ION, DNA (26-MER), I-OnuI_e-hPD1-d, ...
Authors:
Ubilla-Rodriguez, N.C
,
Werther, R.A
,
Stoddard, B.L.
Deposit date:
2021-07-07
Release date:
2022-06-29
Last modified:
2023-10-18
Method:
X-RAY DIFFRACTION (2.42 Å)
Cite:
Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
7RCC
First stage engineered variant of I-OnuI after initial reassembly
Descriptor:
CALCIUM ION, DNA (26-MER), I-OnuI_e-hPD1-b
Authors:
Ubilla-Rodriguez, N.C
,
Werther, R.A
,
Stoddard, B.L.
Deposit date:
2021-07-07
Release date:
2022-06-29
Last modified:
2023-10-18
Method:
X-RAY DIFFRACTION (2.45 Å)
Cite:
Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published
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224931
數據於2024-09-11公開中