7A3W
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![BU of 7a3w by Molmil](/molmil-images/mine/7a3w) | Structure of Imine Reductase from Pseudomonas sp. | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, NAD(P)-dependent oxidoreductase, ... | 著者 | Cuetos, A, Thorpe, T, Turner, N.J, Grogan, G. | 登録日 | 2020-08-18 | 公開日 | 2021-08-25 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Multifunctional biocatalyst for conjugate reduction and reductive amination. Nature, 604, 2022
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7OSN
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![BU of 7osn by Molmil](/molmil-images/mine/7osn) | IRED361 from Micromonospora sp. in complex with NADP+ | 分子名称: | 6-phosphogluconate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Gilio, A.K, Harawa, V, Turner, N, Grogan, G.J. | 登録日 | 2021-06-09 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Synthesis of Stereoenriched Piperidines via Chemo-Enzymatic Dearomatization of Activated Pyridines. J.Am.Chem.Soc., 144, 2022
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5A9R
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![BU of 5a9r by Molmil](/molmil-images/mine/5a9r) | Apo form of Imine reductase from Amycolatopsis orientalis | 分子名称: | ACETATE ION, IMINE REDUCTASE | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | 登録日 | 2015-07-22 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis Acs Catalysis, 6, 2016
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6H7P
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![BU of 6h7p by Molmil](/molmil-images/mine/6h7p) | Reductive Aminase from Aspergillus terreus in complex with NADPH4, cyclohexanone and allyl amine | 分子名称: | CYCLOHEXANONE, Reductive Aminase, [[(2~{R},3~{S},4~{R},5~{R})-5-[(3~{R})-3-aminocarbonylpiperidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, ... | 著者 | Sharma, M, Grogan, G, Mangas-Sanchez, J, Turner, N.J. | 登録日 | 2018-07-31 | 公開日 | 2019-04-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structure of Reductive Aminase from Aspergillus terreus Acs Catalysis, 2018
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5A9T
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![BU of 5a9t by Molmil](/molmil-images/mine/5a9t) | Imine Reductase from Amycolatopsis orientalis in complex with (R)- Methyltetrahydroisoquinoline | 分子名称: | (1R)-1-methyl-1,2,3,4-tetrahydroisoquinoline, ACETATE ION, CALCIUM ION, ... | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | 登録日 | 2015-07-22 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis Acs Catalysis, 6, 2016
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3ZDN
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![BU of 3zdn by Molmil](/molmil-images/mine/3zdn) | D11-C mutant of monoamine oxidase from Aspergillus niger | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, MONOAMINE OXIDASE N | 著者 | Frank, A, Ghislieri, D, Willies, S, Turner, N.J, Grogan, G. | 登録日 | 2012-11-29 | 公開日 | 2013-10-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products. J.Am.Chem.Soc., 135, 2013
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5A9S
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![BU of 5a9s by Molmil](/molmil-images/mine/5a9s) | NADPH complex of Imine Reductase from Amycolatopsis orientalis | 分子名称: | CALCIUM ION, IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | 登録日 | 2015-07-22 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis Acs Catalysis, 6, 2016
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6SLE
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![BU of 6sle by Molmil](/molmil-images/mine/6sle) | Structure of Reductive Aminase from Neosartorya fumigata in complex with NADP+ | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, putative | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | 登録日 | 2019-08-19 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases. Chem Sci, 11, 2020
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2WQ8
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![BU of 2wq8 by Molmil](/molmil-images/mine/2wq8) | Glycan labelling using engineered variants of galactose oxidase obtained by directed evolution | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... | 著者 | Rannes, J.G, Ioannou, A, Willies, S.C, Behrens, C, Grogan, G.J, Flitsch, S.L, Turner, N.J. | 登録日 | 2009-08-14 | 公開日 | 2010-09-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Glycoprotein Labeling Using Engineered Variants of Galactose Oxidase Obtained by Directed Evolution. J.Am.Chem.Soc., 133, 2011
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6SKX
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![BU of 6skx by Molmil](/molmil-images/mine/6skx) | Structure of Reductive Aminase from Neosartorya fumigata | 分子名称: | Oxidoreductase, putative | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | 登録日 | 2019-08-16 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases. Chem Sci, 11, 2020
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5G2P
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![BU of 5g2p by Molmil](/molmil-images/mine/5g2p) | The crystal structure of a S-selective transaminase from Arthrobacter sp. | 分子名称: | CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, TRANSAMINASE | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | 登録日 | 2016-04-12 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases Biochemistry, 55, 2016
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5G0A
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![BU of 5g0a by Molmil](/molmil-images/mine/5g0a) | The crystal structure of a S-selective transaminase from Bacillus megaterium | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | 登録日 | 2016-03-17 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases Biochemistry, 55, 2016
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5FWN
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![BU of 5fwn by Molmil](/molmil-images/mine/5fwn) | Imine Reductase from Amycolatopsis orientalis. Closed form in in complex with (R)- Methyltetrahydroisoquinoline | 分子名称: | (1R)-1-methyl-1,2,3,4-tetrahydroisoquinoline, IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | 登録日 | 2016-02-18 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis Acs Catalysis, 6, 2016
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5G6S
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![BU of 5g6s by Molmil](/molmil-images/mine/5g6s) | Imine reductase from Aspergillus oryzae in complex with NADP(H) and (R)-rasagiline | 分子名称: | IMINE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RASAGILINE | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | 登録日 | 2016-06-23 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A reductive aminase from Aspergillus oryzae. Nat Chem, 9, 2017
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5G6R
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![BU of 5g6r by Molmil](/molmil-images/mine/5g6r) | Imine reductase from Aspergillus oryzae | 分子名称: | IMINE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | 登録日 | 2016-06-23 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | A reductive aminase from Aspergillus oryzae. Nat Chem, 9, 2017
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5G2Q
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![BU of 5g2q by Molmil](/molmil-images/mine/5g2q) | The crystal structure of a S-selective transaminase from Arthrobacter sp. with alanine bound | 分子名称: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, TRANSAMINASE | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | 登録日 | 2016-04-12 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases Biochemistry, 55, 2016
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5G09
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![BU of 5g09 by Molmil](/molmil-images/mine/5g09) | The crystal structure of a S-selective transaminase from Bacillus megaterium bound with R-alpha-methylbenzylamine | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | 登録日 | 2016-03-17 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases Biochemistry, 55, 2016
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6EOH
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![BU of 6eoh by Molmil](/molmil-images/mine/6eoh) | Reductive Aminase from Aspergillus terreus in complex with NADPH and ethyl levulinate | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Reductive Aminase, ethyl levulinate | 著者 | Sharma, M, Grogan, G, Mangas-Sanchez, J, Turner, N.J. | 登録日 | 2017-10-09 | 公開日 | 2018-10-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases Acs Catalysis, 2018
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6EOD
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6EOI
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![BU of 6eoi by Molmil](/molmil-images/mine/6eoi) | Reductive Aminase from Aspergillus terreus in complex with NADPH and ethyl-5-oxohexanoate | 分子名称: | MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Reductive Aminase, ... | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | 登録日 | 2017-10-09 | 公開日 | 2018-10-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases Acs Catalysis, 2018
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