1EYE
 
 | | 1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE | | Descriptor: | DIHYDROPTEROATE SYNTHASE I, MAGNESIUM ION, PTERIN-6-YL-METHYL-MONOPHOSPHATE | | Authors: | Baca, A.M, Sirawaraporn, R, Turley, S, Sirawaraporn, W, Hol, W.G.J. | | Deposit date: | 2000-05-05 | | Release date: | 2000-10-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
J.Mol.Biol., 302, 2000
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4GFT
 | | Malaria invasion machinery protein-Nanobody complex | | Descriptor: | 1,2-ETHANEDIOL, Myosin A tail domain interacting protein, Nanobody | | Authors: | Khamrui, S, Turley, S, Pardon, E, Steyaert, J, Verlinde, C, Fan, E, Bergman, L.W, Hol, W.G.J. | | Deposit date: | 2012-08-03 | | Release date: | 2013-07-03 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
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2GQ2
 | | Mycobacterium tuberculosis ThyX-NADP complex | | Descriptor: | GLYCEROL, IODIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Sampathkumar, P, Turley, S, Sibley, C.H, Hol, W.G. | | Deposit date: | 2006-04-19 | | Release date: | 2006-06-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design.
J.Mol.Biol., 360, 2006
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4GGN
 | | Malaria invasion machinery protein complex | | Descriptor: | Myosin A tail domain interacting protein MTIP, Myosin-A | | Authors: | Khamrui, S, Turley, S, Bergman, L.W, Hol, W.G.J. | | Deposit date: | 2012-08-06 | | Release date: | 2013-07-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
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2NRD
 | | THE STRUCTURE OF CU-NITRITE REDUCTASE FROM ACHROMOBACTER CYCLOCLASTES AT FIVE PH VALUES, WITH NITRITE BOUND AND WITH TYPE II CU DEPLETED | | Descriptor: | COPPER (II) ION, NITRITE REDUCTASE | | Authors: | Adman, E.T, Godden, J.W, Turley, S. | | Deposit date: | 1995-07-03 | | Release date: | 1995-12-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The structure of copper-nitrite reductase from Achromobacter cycloclastes at five pH values, with NO2- bound and with type II copper depleted.
J.Biol.Chem., 270, 1995
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6BQM
 | | Secreted serine protease VesC from Vibrio cholerae | | Descriptor: | serine protease VesC | | Authors: | Park, Y.J, Korotkov, K.V, Delarosa, J.R, Turley, S, DiMaio, F, Hol, W.G.J. | | Deposit date: | 2017-11-28 | | Release date: | 2018-11-28 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease.
Msphere, 5, 2020
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2AFN
 | | STRUCTURE OF ALCALIGENES FAECALIS NITRITE REDUCTASE AND A COPPER SITE MUTANT, M150E, THAT CONTAINS ZINC | | Descriptor: | COPPER (II) ION, NITRITE REDUCTASE | | Authors: | Murphy, M.E.P, Adman, E.T, Turley, S. | | Deposit date: | 1995-07-03 | | Release date: | 1996-08-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Alcaligenes faecalis nitrite reductase and a copper site mutant, M150E, that contains zinc.
Biochemistry, 34, 1995
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4KSR
 | | Crystal Structure of the Vibrio cholerae ATPase GspE Hexamer | | Descriptor: | Type II secretion system protein E, Hemolysin-coregulated protein | | Authors: | Hol, W.G, Turley, S, Lu, C.Y, Park, Y.J, Marionni, S.T, Lee, K, Patrick, M, Sandkvist, M, Bush, M, Shah, R. | | Deposit date: | 2013-05-17 | | Release date: | 2013-09-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Hexamers of the Type II Secretion ATPase GspE from Vibrio cholerae with Increased ATPase Activity.
Structure, 21, 2013
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4KSS
 | | Crystal Structure of Vibrio cholerae ATPase GspsE Hexamer | | Descriptor: | Type II secretion system protein E, hemolysin-coregulated protein | | Authors: | Hol, W.G, Turley, S, Lu, C.Y, Park, Y.J. | | Deposit date: | 2013-05-17 | | Release date: | 2013-09-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (7.58 Å) | | Cite: | Hexamers of the Type II Secretion ATPase GspE from Vibrio cholerae with Increased ATPase Activity.
Structure, 21, 2013
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1FER
 | | STRUCTURE AT PH 6.5 OF FERREDOXIN I FROM AZOTOBACTER VINELANDII AT 2.3 ANGSTROMS RESOLUTION | | Descriptor: | FE3-S4 CLUSTER, FERREDOXIN I, IRON/SULFUR CLUSTER | | Authors: | Merritt, E.A, Stout, G.H, Turley, S, Sieker, L.C, Jensen, L.H, Orme-Johnson, W.H. | | Deposit date: | 1992-09-02 | | Release date: | 1993-04-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure at pH 6.5 of ferredoxin I from Azotobacter vinelandii at 2.3 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
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1JYM
 | | Crystals of Peptide Deformylase from Plasmodium falciparum with Ten Subunits per Asymmetric Unit Reveal Critical Characteristics of the Active Site for Drug Design | | Descriptor: | COBALT (II) ION, Peptide Deformylase | | Authors: | Kumar, A, Nguyen, K.T, Srivathsan, S, Ornstein, B, Turley, S, Hirsh, I, Pei, D, Hol, W.G.J. | | Deposit date: | 2001-09-12 | | Release date: | 2002-03-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design.
Structure, 10, 2002
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2B4V
 | | Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei | | Descriptor: | POTASSIUM ION, RNA editing complex protein MP57 | | Authors: | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | | Deposit date: | 2005-09-26 | | Release date: | 2005-11-22 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
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2B56
 | | Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei | | Descriptor: | MAGNESIUM ION, RNA editing complex protein MP57, URIDINE 5'-TRIPHOSPHATE, ... | | Authors: | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | | Deposit date: | 2005-09-27 | | Release date: | 2005-11-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
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2QAC
 | | The closed MTIP-MyosinA-tail complex from the malaria parasite invasion machinery | | Descriptor: | Myosin A tail domain interacting protein MTIP, Myosin-A | | Authors: | Bosch, J, Turley, S, Roach, C.M, Daly, T.M, Bergman, L.W, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | | Deposit date: | 2007-06-14 | | Release date: | 2007-06-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Closed MTIP-Myosin A-Tail Complex from the Malaria Parasite Invasion Machinery.
J.Mol.Biol., 372, 2007
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1RQC
 | | Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design | | Descriptor: | COBALT (II) ION, formylmethionine deformylase | | Authors: | Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G. | | Deposit date: | 2003-12-04 | | Release date: | 2004-01-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | An improved crystal form of Plasmodium falciparum peptide deformylase
Protein Sci., 13, 2004
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1HXI
 | | AN UNEXPECTED EXTENDED CONFORMATION FOR THE THIRD TPR MOTIF OF THE PEROXIN PEX5 FROM TRYPANOSOMA BRUCEI | | Descriptor: | MAGNESIUM ION, PEROXISOME TARGETING SIGNAL 1 RECEPTOR PEX5 | | Authors: | Kumar, A, Roach, C, Hirsh, I.S, Turley, S, deWalque, S, Michels, P.A.M, Hol, W.G.J. | | Deposit date: | 2001-01-15 | | Release date: | 2001-03-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei.
J.Mol.Biol., 307, 2001
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1EVZ
 | | CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH NAD | | Descriptor: | GLYCEROL-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PENTADECANE | | Authors: | Suresh, S, Turley, S, Opperdoes, F.R, Michels, P.A.M, Hol, W.G.J. | | Deposit date: | 2000-04-21 | | Release date: | 2001-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.
Structure Fold.Des., 8, 2000
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1EVY
 | | CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE | | Descriptor: | GLYCEROL-3-PHOSPHATE DEHYDROGENASE, PENTADECANE | | Authors: | Suresh, S, Turley, S, Opperdoes, F.R, Michels, P.A.M, Hol, W.G.J. | | Deposit date: | 2000-04-20 | | Release date: | 2001-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.
Structure Fold.Des., 8, 2000
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1RL4
 | | Plasmodium falciparum peptide deformylase complex with inhibitor | | Descriptor: | (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, 2-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE, COBALT (II) ION, ... | | Authors: | Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G.J. | | Deposit date: | 2003-11-24 | | Release date: | 2003-12-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | An improved crystal form of Plasmodium falciparum peptide deformylase.
Protein Sci., 13, 2004
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3G20
 | | Crystal structure of the major pseudopilin from the type 2 secretion system of enterohaemorrhagic Escherichia coli | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | Authors: | Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J. | | Deposit date: | 2009-01-30 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
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3FU1
 | | Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio cholerae | | Descriptor: | CALCIUM ION, General secretion pathway protein G, ZINC ION | | Authors: | Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J. | | Deposit date: | 2009-01-13 | | Release date: | 2009-07-28 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
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3GN9
 | | Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio vulnificus | | Descriptor: | CALCIUM ION, D-MALATE, Type II secretory pathway, ... | | Authors: | Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J. | | Deposit date: | 2009-03-16 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
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1HMO
 | | THE STRUCTURE OF DEOXY AND OXY HEMERYTHRIN AT 2.0 ANGSTROMS RESOLUTION | | Descriptor: | ACETYL GROUP, HEMERYTHRIN, MU-OXO-DIIRON, ... | | Authors: | Holmes, M.A, Letrong, I, Turley, S, Sieker, L.C, Stenkamp, R.E. | | Deposit date: | 1990-10-18 | | Release date: | 1992-01-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of deoxy and oxy hemerythrin at 2.0 A resolution.
J.Mol.Biol., 218, 1991
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1MC0
 | | Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains | | Descriptor: | 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE | | Authors: | Martinez, S, Wu, A, Glavas, N, Tang, X, Turley, S, Hol, W, Beavo, J. | | Deposit date: | 2002-08-04 | | Release date: | 2002-10-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
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2AF6
 | | Crystal structure of Mycobacterium tuberculosis Flavin dependent thymidylate synthase (Mtb ThyX) in the presence of co-factor FAD and substrate analog 5-Bromo-2'-Deoxyuridine-5'-Monophosphate (BrdUMP) | | Descriptor: | 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | Authors: | Sampathkumar, P, Turley, S, Ulmer, J.E, Rhie, H.G, Sibley, C.H, Hol, W.G. | | Deposit date: | 2005-07-25 | | Release date: | 2005-10-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structure of the Mycobacterium tuberculosis Flavin Dependent Thymidylate Synthase (MtbThyX) at 2.0A Resolution.
J.Mol.Biol., 352, 2005
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