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PDB: 36 件
8GAT
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Structure of human NDS.1 Fab and 1G01 Fab in complex with influenza virus neuraminidase from A/Indiana/10/2011 (H3N2v), based on consensus cryo-EM map with only Fab 1G01 resolved
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1G01, heavy chain, ...
著者Tsybovsky, Y, Lederhofer, J, Kwong, P.D, Kanekiyo, M.
登録日2023-02-23
公開日2024-02-28
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase.
Immunity, 57, 2024
8GAV
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BU of 8gav by Molmil
Structure of human NDS.3 Fab in complex with influenza virus neuraminidase from A/Darwin/09/2021 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab NDS.3, heavy chain, ...
著者Tsybovsky, Y, Lederhofer, J, Kwong, P.D, Kanekiyo, M.
登録日2023-02-23
公開日2024-02-28
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase.
Immunity, 57, 2024
8GAU
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BU of 8gau by Molmil
Structure of human NDS.1 Fab and 1G01 Fab in complex with influenza virus neuraminidase from A/Indiana/10/2011 (H3N2v)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1G01, heavy chain, ...
著者Tsybovsky, Y, Lederhofer, J, Kwong, P.D, Kanekiyo, M.
登録日2023-02-23
公開日2024-02-28
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase.
Immunity, 57, 2024
4GO2
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BU of 4go2 by Molmil
Crystal structure of the c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with Thio-NADP
分子名称: 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Cytosolic 10-formyltetrahydrofolate dehydrogenase, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2012-08-18
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Chem.Biol.Interact, 202, 2013
4GNZ
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BU of 4gnz by Molmil
Crystal structure of the c707s mutant of c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with NADP
分子名称: Cytosolic 10-formyltetrahydrofolate dehydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Tsybovsky, Y.
登録日2012-08-17
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Chem.Biol.Interact, 202, 2013
4GO0
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BU of 4go0 by Molmil
Crystal structure of the c707s mutant of c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
分子名称: Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Tsybovsky, Y.
登録日2012-08-17
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Chem.Biol.Interact, 202, 2013
2O2Q
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BU of 2o2q by Molmil
Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADP
分子名称: Formyltetrahydrofolate dehydrogenase, GLYCEROL, MAGNESIUM ION, ...
著者Tsybovsky, Y, Donato, H, Krupenko, N.I, Davies, C, Krupenko, S.A.
登録日2006-11-30
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
2O2R
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BU of 2o2r by Molmil
Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
分子名称: Formyltetrahydrofolate dehydrogenase, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Tsybovsky, Y, Donato, H, Krupenko, N.I, Davies, C, Krupenko, S.A.
登録日2006-11-30
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
2O2P
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BU of 2o2p by Molmil
Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase
分子名称: Formyltetrahydrofolate dehydrogenase, GLYCEROL, SULFATE ION
著者Tsybovsky, Y, Donato, H, Krupenko, N.I, Davies, C, Krupenko, S.A.
登録日2006-11-30
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
3RHO
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BU of 3rho by Molmil
Crystal structure of the E673Q MUTANT OF C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with NADP
分子名称: Aldehyde dehydrogenase 1 family, member L1, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2011-04-11
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHP
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BU of 3rhp by Molmil
Crystal structure of the C707A mutant of the C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE
分子名称: Aldehyde dehydrogenase 1 family, member L1, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2011-04-11
公開日2011-05-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHQ
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BU of 3rhq by Molmil
Crystal structure of the C707A mutant of C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with NADP
分子名称: Aldehyde dehydrogenase 1 family, member L1, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2011-04-12
公開日2011-05-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHM
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BU of 3rhm by Molmil
Crystal structure of the E673Q mutant oF C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE
分子名称: Aldehyde dehydrogenase 1 family, member L1, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2011-04-11
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHJ
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BU of 3rhj by Molmil
Crystal structure of the E673A mutant of the C-terminal domain of RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with co-purified NADP
分子名称: Aldehyde dehydrogenase 1 family, member L1, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2011-04-11
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHL
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BU of 3rhl by Molmil
Crystal structure of the E673A/C707A double mutant of the C-Terminal domain of RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with co-purified NADP
分子名称: Aldehyde dehydrogenase 1 family, member L1, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2011-04-11
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHR
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BU of 3rhr by Molmil
Crystal structure of the C707A mutant of the C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with NADPH
分子名称: Aldehyde dehydrogenase 1 family, member L1, GLYCEROL, ...
著者Tsybovsky, Y.
登録日2011-04-12
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
7MTC
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BU of 7mtc by Molmil
Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7MTE
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BU of 7mte by Molmil
Structure of SARS-CoV-2 S2P spike at pH 7.4 refolded by low-pH treatment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7MTD
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BU of 7mtd by Molmil
Structure of aged SARS-CoV-2 S2P spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021
7U9O
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BU of 7u9o by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NE12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ...
著者Tsybovsky, Y, Kwong, P.D, Farci, P.
登録日2022-03-11
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
7U9P
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BU of 7u9p by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NA8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ...
著者Tsybovsky, Y, Kwong, P.D, Farci, P.
登録日2022-03-11
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
8EEV
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BU of 8eev by Molmil
Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20
分子名称: Coat protein, Fab SKT20 heavy chain, Fab SKT20 light chain
著者Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D.
登録日2022-09-07
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8EEU
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BU of 8eeu by Molmil
Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05
分子名称: Coat protein, Fab SKT05 heavy chain, Fab SKT05 light chain
著者Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D.
登録日2022-09-07
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
7RLU
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BU of 7rlu by Molmil
Structure of ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP
分子名称: 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A.
登録日2021-07-26
公開日2022-01-12
最終更新日2022-02-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of putative tumor suppressor ALDH1L1.
Commun Biol, 5, 2022
7RLT
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BU of 7rlt by Molmil
Structure of ligand-free ALDH1L1 (10-formyltetrahydrofolate dehydrogenase)
分子名称: 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase
著者Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A.
登録日2021-07-26
公開日2022-01-12
最終更新日2022-02-02
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of putative tumor suppressor ALDH1L1.
Commun Biol, 5, 2022

 

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