2Q1Y
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2Q1X
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1T5L
| Crystal structure of the DNA repair protein UvrB point mutant Y96A revealing a novel fold for domain 2 | 分子名称: | UvrABC system protein B, ZINC ION | 著者 | Truglio, J.J, Croteau, D.L, Skorvaga, M, DellaVecchia, M.J, Theis, K, Mandavilli, B.S, Van Houten, B, Kisker, C. | 登録日 | 2004-05-04 | 公開日 | 2004-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair Embo J., 23, 2004
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1JRP
| Crystal Structure of Xanthine Dehydrogenase inhibited by alloxanthine from Rhodobacter capsulatus | 分子名称: | CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Truglio, J.J, Theis, K, Leimkuhler, S, Rappa, R, Rajagopalan, K.V, Kisker, C. | 登録日 | 2001-08-14 | 公開日 | 2002-01-11 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus Structure, 10, 2002
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1JRO
| Crystal Structure of Xanthine Dehydrogenase from Rhodobacter capsulatus | 分子名称: | CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Truglio, J.J, Theis, K, Leimkuhler, S, Rappa, R, Rajagopalan, K.V, Kisker, C. | 登録日 | 2001-08-14 | 公開日 | 2002-01-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus Structure, 10, 2002
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1Q51
| Crystal Structure of Mycobacterium tuberculosis MenB in Complex with Acetoacetyl-Coenzyme A, a Key Enzyme in Vitamin K2 Biosynthesis | 分子名称: | ACETOACETYL-COENZYME A, menB | 著者 | Truglio, J.J, Theis, K, Feng, Y, Gajda, R, Machutta, C, Tonge, P.J, Kisker, C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-08-05 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J.Biol.Chem., 278, 2003
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1Q52
| Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K2 Biosynthesis | 分子名称: | menB | 著者 | Truglio, J.J, Theis, K, Feng, Y, Gajda, R, Machutta, C, Tonge, P.J, Kisker, C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-08-05 | 公開日 | 2004-01-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J.Biol.Chem., 278, 2003
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2FDC
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1YD2
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y19F bound to the catalytic divalent cation | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YCZ
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima | 分子名称: | GLYCEROL, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD1
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: magnesium | 分子名称: | GLYCEROL, MAGNESIUM ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD0
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima bound to its catalytic divalent cation: manganese | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD3
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y43F bound to its catalytic divalent cation | 分子名称: | GLYCEROL, MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD4
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant Y29F bound to its catalytic divalent cation | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD6
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Bacillus caldotenax | 分子名称: | CHLORIDE ION, SULFATE ION, UvrC | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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1YD5
| Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima: Point mutant N88A bound to its catalytic divalent cation | 分子名称: | MANGANESE (II) ION, UvrABC system protein C | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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2B35
| Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by triclosan | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | 登録日 | 2005-09-19 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis ACS Chem.Biol., 1, 2006
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2B36
| Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by 5-pentyl-2-phenoxyphenol | 分子名称: | 5-PENTYL-2-PHENOXYPHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | 登録日 | 2005-09-19 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis ACS Chem.Biol., 1, 2006
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3T88
| Crystal structure of Escherichia coli MenB in complex with substrate analogue, OSB-NCoA | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ... | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | 登録日 | 2011-08-01 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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3T8A
| Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | 登録日 | 2011-08-01 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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3T8B
| Crystal structure of Mycobacterium tuberculosis MenB with altered hexameric assembly | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | 登録日 | 2011-08-01 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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3T89
| Crystal structure of Escherichia coli MenB, the 1,4-dihydroxy-2-naphthoyl-CoA synthase in vitamin K2 biosynthesis | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL, MALONATE ION | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | 登録日 | 2011-08-01 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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2B37
| Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by 5-octyl-2-phenoxyphenol | 分子名称: | 5-OCTYL-2-PHENOXYPHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | 登録日 | 2005-09-19 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis ACS Chem.Biol., 1, 2006
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2JJY
| Crystal structure of Francisella tularensis enoyl reductase (ftFabI) with bound NAD | 分子名称: | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Luckner, S.R, Lu, H, Truglio, J.J, Tonge, P.J, Kisker, C. | 登録日 | 2008-04-25 | 公開日 | 2009-02-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Slow-Onset Inhibition of the Fabi Enoyl Reductase from Francisella Tularensis: Residence Time and in Vivo Activity Acs Chem.Biol., 4, 2009
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2W55
| Crystal Structure of Xanthine Dehydrogenase (E232Q variant) from Rhodobacter capsulatus in Complex with Hypoxanthine | 分子名称: | BARIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Doebbler, J.A, Truglio, J.J, Leimkuhler, S, Kisker, C. | 登録日 | 2008-12-04 | 公開日 | 2008-12-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Mechanism of Substrate and Inhibitor Binding of Rhodobacter Capsulatus Xanthine Dehydrogenase. J.Biol.Chem., 284, 2009
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