6E16
 
 | | Ternary structure of c-Myc-TBP-TAF1 | | 分子名称: | Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein | | 著者 | Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2018-07-09 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
|
|
6E24
 | | Ternary structure of c-Myc-TBP-TAF1 | | 分子名称: | Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein | | 著者 | Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2018-07-10 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
|
|
5C7J
 | | CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
|
|
6VAN
 | | Crystal structure of caltubin from the great pond snail | | 分子名称: | 1,2-ETHANEDIOL, Caltubin, EF-hand, ... | | 著者 | Dong, A, Li, A, Zhang, Q, Barszczyk, A, Chern, Y.H, Arrowsmith, C.H, Edwards, A.M, Zhong, Z.P, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2019-12-17 | | 公開日 | 2020-12-23 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Cell-penetrating caltubin promotes neurite outgrowth and regrowth through calcium-dependent microtubule regulation
to be published
|
|
5C7M
 | | CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
|
|
7M2F
 | | CDK2 with compound 14 inhibitor with carboxylate | | 分子名称: | Cyclin-dependent kinase 2, [(1r,4r)-4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}cyclohexyl]acetic acid | | 著者 | Longenecker, K.L, Qiu, W, Korepanova, A, Tong, Y. | | 登録日 | 2021-03-16 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.632 Å) | | 主引用文献 | Balancing Properties with Carboxylates: A Lead Optimization Campaign for Selective and Orally Active CDK9 Inhibitors.
Acs Med.Chem.Lett., 12, 2021
|
|
6MIW
 | | WWE domain of human HUWE1 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, E3 ubiquitin-protein ligase HUWE1, UNKNOWN ATOM OR ION | | 著者 | Halabelian, L, Loppnau, P, Tempel, W, Wong, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2018-09-20 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | WWE domain of human HUWE1
To Be Published
|
|
1NMI
 | | Solution structure of the imidazole complex of iso-1 cytochrome c | | 分子名称: | Cytochrome c, iso-1, HEME C, ... | | 著者 | Yao, Y, Tong, Y, Liu, G, Wang, J, Zheng, J, Tang, W. | | 登録日 | 2003-01-10 | | 公開日 | 2003-02-04 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the imidazole complex of iso-1 cytochrome c
To be Published
|
|
6BY9
 | | Crystal structure of EHMT1 | | 分子名称: | Histone-lysine N-methyltransferase EHMT1, UNKNOWN ATOM OR ION | | 著者 | Dong, A, Wei, Y, Li, A, Tempel, W, Han, S, Sunnerhagen, M, Penn, L, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-12-20 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of EHMT1
to be published
|
|
5VBD
 | | Crystal structure of a putative UBL domain of USP9X | | 分子名称: | UNKNOWN ATOM OR ION, USP9X | | 著者 | Dong, A, Chern, Y, Hou, F, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-29 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of a putative UBL domain of USP9X
to be published
|
|
5VBT
 | | Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor | | 分子名称: | UBH04 | | 著者 | DONG, A, DONG, X, LIU, L, GUO, Y, LI, Y, ZHANG, W, WALKER, J.R, SIDHU, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-30 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published
|
|
6CVZ
 | | Crystal structure of the WD40-repeat of RFWD3 | | 分子名称: | E3 ubiquitin-protein ligase RFWD3, MAGNESIUM ION | | 著者 | DONG, A, LOPPNAU, P, SEITOVA, A, HUTCHINSON, A, TEMPEL, W, WEI, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, TONG, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2018-03-29 | | 公開日 | 2018-06-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Target highlights in CASP13: Experimental target structures through the eyes of their authors.
Proteins, 87, 2019
|
|
1M60
 | | Solution Structure of Zinc-substituted cytochrome c | | 分子名称: | ZINC SUBSTITUTED HEME C, Zinc-substituted cytochrome c | | 著者 | Qian, C, Yao, Y, Tong, Y, Wang, J, Tang, W. | | 登録日 | 2002-07-11 | | 公開日 | 2002-08-07 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of zinc-substituted cytochrome c.
J.Biol.Inorg.Chem., 8, 2003
|
|
5WCH
 | | Crystal structure of the catalytic domain of human USP9X | | 分子名称: | Probable ubiquitin carboxyl-terminal hydrolase FAF-X, UNKNOWN ATOM OR ION, ZINC ION | | 著者 | Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-06-30 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
4Z30
 | | Crystal structure of the ROQ domain of human Roquin-2 | | 分子名称: | Roquin-2, UNKNOWN ATOM OR ION | | 著者 | DONG, A, ZHANG, Q, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-03-30 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.
Sci Rep, 5, 2015
|
|
5TF2
 | | CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF THE HUMAN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN | | 分子名称: | Prolactin regulatory element-binding protein, UNKNOWN ATOM OR ION | | 著者 | Walker, J.R, Zhang, Q, Dong, A, Wernimont, A, Li, Y, He, H, Tempel, W, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Chen, Z, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-23 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF THE HUMAN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN (CASP target)
To be published
|
|
4QN1
 | | Crystal Structure of a Functionally Uncharacterized Domain of E3 Ubiquitin Ligase SHPRH | | 分子名称: | E3 ubiquitin-protein ligase SHPRH, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Dong, A, Zhang, Q, Li, Y, Walker, J.R, Guan, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2014-06-17 | | 公開日 | 2014-08-13 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal structure of a Function Uncharacterized Domain of E3 Ubiquitin Ligase SHPRH
To be Published
|
|
4QT6
 | | Crystal structure of the SPRY domain of human HERC1 | | 分子名称: | FORMAMIDE, Probable E3 ubiquitin-protein ligase HERC1, UNKNOWN ATOM OR ION | | 著者 | Dong, A, Hu, J, Guan, X, Wernimont, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2014-07-07 | | 公開日 | 2015-01-07 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal structure of the SPRY domain of human HERC1
To be Published
|
|
4RXX
 | | Crystal Structure of the N-terminal Domain of Human Ubiquitin Specific Protease 38 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Dong, A, Shen, L, Hu, J, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2014-12-12 | | 公開日 | 2015-01-21 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Crystal Structure of the N-terminal Domain of Human Ubiquitin Specific Protease 38
to be published
|
|
5JJX
 | | Crystal structure of the HAT domain of sart3 | | 分子名称: | CHLORIDE ION, Squamous cell carcinoma antigen recognized by T-cells 3, UNKNOWN ATOM OR ION | | 著者 | DONG, A, ZHANG, Q, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2016-04-25 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the HAT domain of sart3
to be published
|
|
5H9M
 | | Crystal structure of siah2 SBD domain | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase SIAH2, PENTAETHYLENE GLYCOL, ... | | 著者 | Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-12-28 | | 公開日 | 2016-02-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.761 Å) | | 主引用文献 | Crystal structure of siah2 SBD domain
to be published
|
|
5JJW
 | | Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain | | 分子名称: | 1,2-ETHANEDIOL, Squamous cell carcinoma antigen recognized by T-cells 3, UNKNOWN ATOM OR ION, ... | | 著者 | Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2016-04-25 | | 公開日 | 2016-05-04 | | 最終更新日 | 2016-07-06 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain
to be published
|
|
1K9O
 | | CRYSTAL STRUCTURE OF MICHAELIS SERPIN-TRYPSIN COMPLEX | | 分子名称: | ALASERPIN, TRYPSIN II ANIONIC | | 著者 | Ye, S, Cech, A.L, Belmares, R, Bergstrom, R.C, Tong, Y, Corey, D.R, Kanost, M.R, Goldsmith, E.J. | | 登録日 | 2001-10-29 | | 公開日 | 2001-11-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The structure of a Michaelis serpin-protease complex.
Nat.Struct.Biol., 8, 2001
|
|
7WAT
 | |
4L1M
 | | Structure of the first RCC1-like domain of HERC2 | | 分子名称: | E3 ubiquitin-protein ligase HERC2, SULFATE ION, UNKNOWN ATOM OR ION | | 著者 | Tempel, W, Khan, M.B, Dong, A, Hu, J, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2013-06-03 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the first RCC1-like domain of HERC2
TO BE PUBLISHED
|
|
