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7YF6
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Crystal structure of HIV-1 protease in complex with macrocyclic peptide
Descriptor: MAGNESIUM ION, Macrocyclic Peptide, Protease
Authors:Kusumoto, Y, Sato, S, Yamada, T, Kozono, I, Nakata, Z, Asada, N, Mitsuki, S, Wakasa-Morimoto, C, Tohru, M, Watanabe, A, Hayashi, K, Mikamiyama, H.
Deposit date:2022-07-07
Release date:2022-11-02
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization.
Acs Med.Chem.Lett., 13, 2022

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