5ESP
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6M9G
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![BU of 6m9g by Molmil](/molmil-images/mine/6m9g) | BbvCI B2 dimer with Ta6Br14 clusters | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, BROMIDE ION, ... | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2018-08-23 | Release date: | 2018-11-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI. Nucleic Acids Res., 47, 2019
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6MAG
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![BU of 6mag by Molmil](/molmil-images/mine/6mag) | native BbvCI B2 dimer in space group C222 | Descriptor: | ACETATE ION, BbvCI endonuclease subunit 2, GLYCEROL, ... | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2018-08-27 | Release date: | 2018-11-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI. Nucleic Acids Res., 47, 2019
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7SQ5
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![BU of 7sq5 by Molmil](/molmil-images/mine/7sq5) | Designed trefoil knot protein, variant 3 | Descriptor: | Designed trefoil knot protein, variant 3, SODIUM ION | Authors: | Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. | Deposit date: | 2021-11-04 | Release date: | 2022-11-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.205 Å) | Cite: | De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
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7RDR
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7UNJ
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![BU of 7unj by Molmil](/molmil-images/mine/7unj) | De novo designed chlorophyll dimer protein with Zn pheophorbide a methyl ester matching geometry of purple bacterial special pair, SP1-ZnPPaM | Descriptor: | 1,2-ETHANEDIOL, SP1-ZnPPaM designed chlorophyll dimer protein, SULFATE ION, ... | Authors: | Kennedy, M.A, Stoddard, B.L, Ennist, N.M. | Deposit date: | 2022-04-11 | Release date: | 2023-04-19 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | De novo design of proteins housing excitonically coupled chlorophyll special pairs. Nat.Chem.Biol., 2024
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7UNH
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7UNI
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![BU of 7uni by Molmil](/molmil-images/mine/7uni) | De novo designed chlorophyll dimer protein with Zn pheophorbide a methyl ester, SP2-ZnPPaM | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, SP2-ZnPPaM designed chlorophyll dimer protein, ... | Authors: | Kennedy, M.A, Stoddard, B.L, Ennist, N.M. | Deposit date: | 2022-04-11 | Release date: | 2023-04-19 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | De novo design of proteins housing excitonically coupled chlorophyll special pairs. Nat.Chem.Biol., 2024
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4LQ0
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1U3E
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![BU of 1u3e by Molmil](/molmil-images/mine/1u3e) | DNA binding and cleavage by the HNH homing endonuclease I-HmuI | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 36-MER, ... | Authors: | Shen, B.W, Landthaler, M, Shub, D.A, Stoddard, B.L. | Deposit date: | 2004-07-21 | Release date: | 2004-08-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | DNA Binding and Cleavage by the HNH Homing Endonuclease I-HmuI. J.Mol.Biol., 342, 2004
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301D
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![BU of 301d by Molmil](/molmil-images/mine/301d) | CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MG(II)-SOAKED | Descriptor: | MAGNESIUM ION, RNA HAMMERHEAD RIBOZYME | Authors: | Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A. | Deposit date: | 1996-12-14 | Release date: | 1997-01-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science, 274, 1996
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299D
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![BU of 299d by Molmil](/molmil-images/mine/299d) | CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: THE HAMMERHEAD RIBOZYME | Descriptor: | RNA HAMMERHEAD RIBOZYME | Authors: | Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A. | Deposit date: | 1996-12-14 | Release date: | 1997-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science, 274, 1996
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8EIL
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![BU of 8eil by Molmil](/molmil-images/mine/8eil) | C-Terminal Domain of BrxL from Acinetobacter BREX type I phage restriction system | Descriptor: | MALONIC ACID, Protease Lon-related BREX system protein BrxL, SUCCINIC ACID | Authors: | Doyle, L.A, Stoddard, B.L, Kaiser, B. | Deposit date: | 2022-09-15 | Release date: | 2023-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor. Nucleic Acids Res., 51, 2023
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6MAF
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![BU of 6maf by Molmil](/molmil-images/mine/6maf) | native BbvCI A2B2 tetramer at low resolution | Descriptor: | BbvCI endonuclease subunit 1, BbvCI endonuclease subunit 2 | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2018-08-27 | Release date: | 2018-11-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.79 Å) | Cite: | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI. Nucleic Acids Res., 47, 2019
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5JSB
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![BU of 5jsb by Molmil](/molmil-images/mine/5jsb) | Crystal structure of Mcl1-inhibitor complex | Descriptor: | Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 inhibitor | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2016-05-07 | Release date: | 2016-11-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer. Elife, 5, 2016
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4LOX
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6UW0
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8EMC
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8EMH
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5THG
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300D
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![BU of 300d by Molmil](/molmil-images/mine/300d) | CAPTURING THE STRUCTURE OF A CATALYTIC RNA INTERMEDIATE: RNA HAMMERHEAD RIBOZYME, MN(II)-SOAKED | Descriptor: | MANGANESE (II) ION, RNA HAMMERHEAD RIBOZYME | Authors: | Scott, W.G, Murray, J.B, Arnold, J.R.P, Stoddard, B.L, Klug, A. | Deposit date: | 1996-12-14 | Release date: | 1997-01-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science, 274, 1996
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1MOW
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![BU of 1mow by Molmil](/molmil-images/mine/1mow) | E-DreI | Descriptor: | 5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*G)-3', 5'-D(*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*GP*G)-3', GLYCEROL, ... | Authors: | Chevalier, B.S, Kortemme, T, Chadsey, M.S, Baker, D, Monnat Jr, R.J, Stoddard, B.L. | Deposit date: | 2002-09-10 | Release date: | 2002-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Design, Activity and Structure of a Highly Specific Artificial Endonuclease Mol.Cell, 10, 2002
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4IWW
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![BU of 4iww by Molmil](/molmil-images/mine/4iww) | Computational Design of an Unnatural Amino Acid Metalloprotein with Atomic Level Accuracy | Descriptor: | COBALT (II) ION, SULFATE ION, Unnatural Amino Acid Mediated Metalloprotein | Authors: | Mills, J, Bolduc, J, Khare, S, Stoddard, B, Baker, D. | Deposit date: | 2013-01-24 | Release date: | 2013-08-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Computational design of an unnatural amino Acid dependent metalloprotein with atomic level accuracy. J.Am.Chem.Soc., 135, 2013
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4OYD
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![BU of 4oyd by Molmil](/molmil-images/mine/4oyd) | Crystal structure of a computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein | Descriptor: | 1,2-ETHANEDIOL, Apoptosis regulator BHRF1, Computationally designed Inhibitor | Authors: | Shen, B, Procko, E, Baker, D, Stoddard, B. | Deposit date: | 2014-02-11 | Release date: | 2014-07-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A computationally designed inhibitor of an epstein-barr viral bcl-2 protein induces apoptosis in infected cells. Cell, 157, 2014
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3LDY
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![BU of 3ldy by Molmil](/molmil-images/mine/3ldy) | An extraordinary mechanism of DNA perturbation exhibited by the rare-cutting HNH restriction endonuclease PacI | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*AP*GP*GP*CP*TP*TP*A)-3'), DNA (5'-D(P*AP*TP*TP*AP*AP*GP*CP*CP*TP*C)-3'), ... | Authors: | Shen, B.W, Heiter, D, Chan, S.-H, Xu, S.-Y, Wilson, G, Stoddard, B.L. | Deposit date: | 2010-01-13 | Release date: | 2010-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI. Structure, 18, 2010
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