4ZAH
 
 | | Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12 | | 分子名称: | [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3,4-bis(oxidanyl)oxan-2-yl] hydrogen phosphate, dTDP-4-amino-4,6-dideoxygalactose transaminase | | 著者 | Wang, F, Singh, S, Cao, H, Xu, W, Miller, M.D, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-04-13 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases.
Acs Chem.Biol., 10, 2015
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1NQS
 | | Structural Characterisation of the Holliday Junction formed by the sequence d(TCGGTACCGA) at 1.97 A | | 分子名称: | 5'-d(TpCpGpGpTpApCpCpGpA)-3', CALCIUM ION | | 著者 | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | | 登録日 | 2003-01-22 | | 公開日 | 2003-02-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural Analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG
To be Published
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1NVY
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4ZAS
 | | Crystal structure of sugar aminotransferase CalS13 from Micromonospora echinospora | | 分子名称: | CalS13, SULFATE ION, THYMIDINE-5'-DIPHOSPHATE, ... | | 著者 | Wang, F, Singh, S, Miller, M.D, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-04-13 | | 公開日 | 2015-04-29 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structure characterization of sugar aminotransferases CalS13 and WecE provides the basis for a unifying structural model for stereochemical outcome.
To Be Published
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4M7P
 | | Ensemble refinement of protein crystal structure of macrolide glycosyltransferases OleD | | 分子名称: | Oleandomycin glycosyltransferase, SODIUM ION | | 著者 | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-08-12 | | 公開日 | 2013-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD
To be Published
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6V04
 | | DynU16 crystal structure, a putative protein in the dynemicin biosynthetic locus | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ... | | 著者 | Alvarado, S.K, Miller, M.D, Bhardwaj, M, Thorson, J.S, Van Lanen, S.G, Phillips Jr, G.N. | | 登録日 | 2019-11-18 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural characterization of DynU16, a START/Bet v1-like protein involved in dynemicin biosynthesis.
Acta Crystallogr.,Sect.F, 77, 2021
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4FNE
 | | X-ray Crystal structure of the Ancestral 3-keto steroid receptor - DOC complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, DESOXYCORTICOSTERONE, ... | | 著者 | Ortlund, E.A, Colucci, J.K, Thornton, J, Eick, G, Harms, M. | | 登録日 | 2012-06-19 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Evolution of minimal specificity and promiscuity in steroid hormone receptors.
PLoS Genet, 8, 2012
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1NT8
 | | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 2.00 A | | 分子名称: | 5'-d(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | | 著者 | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | | 登録日 | 2003-01-29 | | 公開日 | 2003-02-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Analysis of two Holliday Junctions formed by the sequences TCGGTACCGA and CCGGTACCGG
To be Published
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1IIM
 | | thymidylyltransferase complexed with TTP | | 分子名称: | THYMIDINE-5'-TRIPHOSPHATE, glucose-1-phosphate thymidylyltransferase | | 著者 | Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B. | | 登録日 | 2001-04-23 | | 公開日 | 2001-05-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
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4FN9
 | | X-ray Crystal structure of the Ancestral 3-keto steroid receptor - Progesterone complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, GLYCEROL, ... | | 著者 | Colucci, J.K, Ortlund, E.A, Thornton, J.W. | | 登録日 | 2012-06-19 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Evolution of minimal specificity and promiscuity in steroid hormone receptors.
PLoS Genet., 8, 2012
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1NVN
 | | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 1.8 A | | 分子名称: | 5'-D(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | | 著者 | Cardin, C.J, Gale, B.C, Thorpe, J.H, Teixeira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | | 登録日 | 2003-02-04 | | 公開日 | 2003-02-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG
To be Published
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1K2L
 | | STRUCTURAL CHARACTERIZATION OF BISINTERCALATION IN HIGHER-ORDER DNA AT A JUNCTION-LIKE QUADRUPLEX | | 分子名称: | 5'-D(*CP*GP*TP*AP*CP*G)-3', BIS-(9-OCTYLAMINO(2-DIMETHYLAMINOETHYL)ACRIDINE-4-CARBOXAMIDE, COBALT (II) ION | | 著者 | Teixeira, S.C.M, Thorpe, J.H, Todd, A.K, Powell, H.R, Adams, A, Wakelin, L.P.G, Denny, W.A, Cardin, C.J. | | 登録日 | 2001-09-28 | | 公開日 | 2002-10-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Characterisation of Bisintercalation in Higher-order DNA at a Junction-like Quadruplex
J.MOL.BIOL., 323, 2002
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1FPW
 | | STRUCTURE OF YEAST FREQUENIN | | 分子名称: | CALCIUM ION, CALCIUM-BINDING PROTEIN NCS-1 | | 著者 | Ames, J.B, Hendricks, K.B, Strahl, T, Huttner, I.G, Thorner, J. | | 登録日 | 2000-08-31 | | 公開日 | 2000-10-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and calcium-binding properties of Frq1, a novel calcium sensor in the yeast Saccharomyces cerevisiae.
Biochemistry, 39, 2000
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3OTI
 | | Crystal Structure of CalG3, Calicheamicin Glycostyltransferase, TDP and calicheamicin T0 bound form | | 分子名称: | CHLORIDE ION, CalG3, Calicheamicin T0, ... | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2010-09-11 | | 公開日 | 2010-12-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.597 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4GF5
 | | Crystal Structure of Calicheamicin Methyltransferase, CalS11 | | 分子名称: | CalS11, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | 著者 | Helmich, K.E, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2012-08-02 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 |
to be published
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4PIW
 | | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12 | | 分子名称: | TDP-4-keto-6-deoxy-D-glucose transaminase family protein | | 著者 | Wang, F, Xu, W, Helmich, K.E, Singh, S, Yennamalli, R.M, Miller, M.D, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-05-09 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12
To Be Published
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2L65
 | | HADDOCK calculated model of the complex of the resistance protein CalC and Calicheamicin-Gamma | | 分子名称: | 2,4-dideoxy-4-(ethylamino)-3-O-methyl-alpha-L-threo-pentopyranose-(1-2)-4-amino-4,6-dideoxy-beta-D-glucopyranose, 2,6-dideoxy-4-thio-beta-D-allopyranose, 3-O-methyl-alpha-L-rhamnopyranose, ... | | 著者 | Singh, S, Markley, J.L, Thorson, J.S, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-11-15 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insight into the self-sacrifice mechanism of enediyne resistance.
Acs Chem.Biol., 1, 2006
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5DU2
 | | Structural analysis of EspG2 glycosyltransferase | | 分子名称: | EspG2 glycosyltransferase | | 著者 | Michalska, K, Elshahawi, S.I, Bigelow, L, Babnigg, G, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-09-18 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural analysis of EspG2 glycosyltransferase
To Be Published
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2HDL
 | | Solution structure of Brak/CXCL14 | | 分子名称: | Small inducible cytokine B14 | | 著者 | Peterson, F.C, Thorpe, J.A, Harder, A.G, Volkman, B.F, Schwarze, S.R. | | 登録日 | 2006-06-20 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Determinants Involved in the Regulation of CXCL14/BRAK Expression by the 26 S Proteasome.
J.Mol.Biol., 363, 2006
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2GKD
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3RSC
 | | Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form | | 分子名称: | CalG2, Calicheamicin T0, PHOSPHATE ION, ... | | 著者 | Chang, A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2011-05-02 | | 公開日 | 2011-08-10 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3GWZ
 | | Structure of the Mitomycin 7-O-methyltransferase MmcR | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, MmcR, ... | | 著者 | Singh, S, Chang, A, Bingman, C.A, Phillips Jr, G.N, Thorson, J.S. | | 登録日 | 2009-04-01 | | 公開日 | 2010-04-07 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Structural characterization of the mitomycin 7-O-methyltransferase.
Proteins, 79, 2011
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3GXO
 | | Structure of the Mitomycin 7-O-methyltransferase MmcR with bound Mitomycin A | | 分子名称: | CALCIUM ION, MmcR, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Singh, S, Chang, A, Bingman, C.A, Phillips Jr, G.N, Thorson, J.S. | | 登録日 | 2009-04-02 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural characterization of the mitomycin 7-O-methyltransferase.
Proteins, 79, 2011
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4XR9
 | | Crystal structure of CalS8 from Micromonospora echinospora cocrystallized with NAD and TDP-glucose | | 分子名称: | CalS8, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Michalska, K, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-01-20 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of CalS8 from Micromonospora echinospora
To Be Published
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3LST
 | | Crystal Structure of CalO1, Methyltransferase in Calicheamicin Biosynthesis, SAH bound form | | 分子名称: | 1,2-ETHANEDIOL, CalO1 Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-02-12 | | 公開日 | 2010-03-02 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 67, 2011
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