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PDB: 143 results

7N4F
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BU of 7n4f by Molmil
Ni-bound crystal structure of the engineered cyt cb562 variant, AB2-H100A, crystallized in the presence of Ni(II)
Descriptor: HEME C, NICKEL (II) ION, Soluble cytochrome b562
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-06-04
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Overcoming universal restrictions on metal selectivity by protein design.
Nature, 603, 2022
7N4G
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BU of 7n4g by Molmil
Co-bound crystal structure of the engineered cyt cb562 variant, AB2-H100A, crystallized in the presence of Co(II)
Descriptor: COBALT (II) ION, HEME C, Soluble cytochrome b562
Authors:Choi, T.S, Tezcan, F.A.
Deposit date:2021-06-04
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Overcoming universal restrictions on metal selectivity by protein design.
Nature, 603, 2022
8SJH
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BU of 8sjh by Molmil
Zn-Bound Structure of Computationally Designed Homotrimer TP1
Descriptor: CALCIUM ION, CHLORIDE ION, Topoisomerase 1, ...
Authors:Hoffnagle, A.M, Tezcan, F.A.
Deposit date:2023-04-18
Release date:2023-07-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Atomically Accurate Design of Metalloproteins with Predefined Coordination Geometries.
J.Am.Chem.Soc., 145, 2023
8SJG
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BU of 8sjg by Molmil
Zn-Bound Structure of Computationally Designed Homotrimer Tet4
Descriptor: Tet4, ZINC ION
Authors:Hoffnagle, A.M, Tezcan, F.A.
Deposit date:2023-04-18
Release date:2023-07-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Atomically Accurate Design of Metalloproteins with Predefined Coordination Geometries.
J.Am.Chem.Soc., 145, 2023
8SJF
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BU of 8sjf by Molmil
Apo Structure of Computationally Designed Homotrimer Tet4
Descriptor: Tet4
Authors:Hoffnagle, A.H, Tezcan, F.A.
Deposit date:2023-04-18
Release date:2023-07-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Atomically Accurate Design of Metalloproteins with Predefined Coordination Geometries.
J.Am.Chem.Soc., 145, 2023
8SJI
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BU of 8sji by Molmil
Apo Structure of Computationally Designed Homotrimer TP1
Descriptor: CALCIUM ION, CHLORIDE ION, Topoisomerase 1
Authors:Hoffnagle, A.M, Tezcan, F.A.
Deposit date:2023-04-18
Release date:2023-07-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Atomically Accurate Design of Metalloproteins with Predefined Coordination Geometries.
J.Am.Chem.Soc., 145, 2023
5XZI
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BU of 5xzi by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, AB5
Descriptor: CHLORIDE ION, HEME C, Soluble cytochrome b562, ...
Authors:Song, W.J, Tezcan, F.A.
Deposit date:2017-07-12
Release date:2017-12-20
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases.
J. Am. Chem. Soc., 139, 2017
5XZJ
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BU of 5xzj by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, C96T/AB5
Descriptor: CHLORIDE ION, HEME C, Soluble cytochrome b562, ...
Authors:Song, W.J, Tezcan, F.A.
Deposit date:2017-07-12
Release date:2017-12-20
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases.
J. Am. Chem. Soc., 139, 2017
5WPN
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BU of 5wpn by Molmil
Zn-bound Structure of Chaetopterus variopedatus Ferritin
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:De Meulenaere, E, Bailey, J.B, Tezcan, F.A, Deheyn, D.
Deposit date:2017-08-05
Release date:2017-12-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:First biochemical and crystallographic characterization of a fast-performing ferritin from a marine invertebrate.
Biochem. J., 474, 2017
5UP8
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BU of 5up8 by Molmil
Crystal Structure of the Zn-bound Human Heavy-Chain variant 122H-delta C-star with para-benzenedihydroxamate
Descriptor: Ferritin heavy chain, N,N'-dihydroxybenzene-1,4-dicarboxamide, SODIUM ION, ...
Authors:Bailey, J.B, Zhang, L, Chiong, J.C, Ahn, S, Tezcan, F.A.
Deposit date:2017-02-01
Release date:2017-06-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.631 Å)
Cite:Synthetic Modularity of Protein-Metal-Organic Frameworks.
J. Am. Chem. Soc., 139, 2017
5UP9
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BU of 5up9 by Molmil
Crystal Structure of Zn-bound Human Heavy-Chain ferritin variant 122H-delta C-star with para-xylenedihydroxamate
Descriptor: 2,2'-(1,4-phenylene)bis(N-hydroxyacetamide), DI(HYDROXYETHYL)ETHER, Ferritin heavy chain, ...
Authors:Bailey, J.B, Zhang, L, Chiong, J.A, Ahn, S, Tezcan, F.A.
Deposit date:2017-02-01
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Synthetic Modularity of Protein-Metal-Organic Frameworks.
J. Am. Chem. Soc., 139, 2017
5UP7
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BU of 5up7 by Molmil
Crystal Structure of the Ni-bound Human Heavy-Chain Ferritin 122H-delta C-star variant
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Bailey, J.B, Zhang, L, Chiong, J.A, Ahn, S, Tezcan, F.A.
Deposit date:2017-02-01
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Synthetic Modularity of Protein-Metal-Organic Frameworks.
J. Am. Chem. Soc., 139, 2017
7UT9
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BU of 7ut9 by Molmil
CryoEM structure of Azotobacter vinelandii nitrogenase complex (1:1 FeP:MoFeP, ADP/ATP-bound) during catalytic N2 reduction
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rutledge, H.L, Cook, B, Tezcan, F.A, Herzik, M.A.
Deposit date:2022-04-26
Release date:2022-08-17
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Structures of the nitrogenase complex prepared under catalytic turnover conditions.
Science, 377, 2022
7UT8
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BU of 7ut8 by Molmil
CryoEM structure of Azotobacter vinelandii nitrogenase complex (1:1 FeP:MoFeP, ATP-bound) during catalytic N2 reduction
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ...
Authors:Rutledge, H.L, Cook, B, Tezcan, F.A, Herzik, M.A.
Deposit date:2022-04-26
Release date:2022-08-17
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:Structures of the nitrogenase complex prepared under catalytic turnover conditions.
Science, 377, 2022
7UT6
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BU of 7ut6 by Molmil
C1 symmetric cryoEM structure of Azotobacter vinelandii MoFeP under non-turnover conditions
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ...
Authors:Rutledge, H.L, Cook, B, Tezcan, F.A, Herzik, M.A.
Deposit date:2022-04-26
Release date:2022-08-17
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (1.91 Å)
Cite:Structures of the nitrogenase complex prepared under catalytic turnover conditions.
Science, 377, 2022
7UTA
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BU of 7uta by Molmil
CryoEM structure of Azotobacter vinelandii nitrogenase complex (2:1 FeP:MoFeP) inhibited by BeFx during catalytic N2 reduction
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM, ...
Authors:Rutledge, H.L, Cook, B.D, Nguyen, H.P.M, Tezcan, F.A, Herzik, M.A.
Deposit date:2022-04-26
Release date:2022-08-17
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structures of the nitrogenase complex prepared under catalytic turnover conditions.
Science, 377, 2022
7UT7
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BU of 7ut7 by Molmil
C2 symmetric cryoEM structure of Azotobacter vinelandii MoFeP under non-turnover conditions
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ...
Authors:Rutledge, H.L, Cook, B.D, Tezcan, F.A, Herzik, M.A.
Deposit date:2022-04-26
Release date:2022-08-17
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (1.91 Å)
Cite:Structures of the nitrogenase complex prepared under catalytic turnover conditions.
Science, 377, 2022
5KOJ
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BU of 5koj by Molmil
Nitrogenase MoFeP protein in the IDS oxidized state
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ...
Authors:Owens, C.P, Tezcan, F.A.
Deposit date:2016-06-30
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:Tyrosine-Coordinated P-Cluster in G. diazotrophicus Nitrogenase: Evidence for the Importance of O-Based Ligands in Conformationally Gated Electron Transfer.
J.Am.Chem.Soc., 138, 2016
5KOH
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BU of 5koh by Molmil
Nitrogenase MoFeP from Gluconacetobacter diazotrophicus in dithionite reduced state
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ...
Authors:Owens, C.P, Tezcan, F.A.
Deposit date:2016-06-30
Release date:2016-09-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Tyrosine-Coordinated P-Cluster in G. diazotrophicus Nitrogenase: Evidence for the Importance of O-Based Ligands in Conformationally Gated Electron Transfer.
J.Am.Chem.Soc., 138, 2016
5L32
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BU of 5l32 by Molmil
Crystal structure of the Zn-RIDC1 complex bearing six interfacial disulfide bonds
Descriptor: HEME C, HEXAETHYLENE GLYCOL, Soluble cytochrome b562, ...
Authors:Churchfield, L.A, Tezcan, F.A.
Deposit date:2016-08-02
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:De Novo Design of an Allosteric Metalloprotein Assembly with Strained Disulfide Bonds.
J.Am.Chem.Soc., 138, 2016
5BU7
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BU of 5bu7 by Molmil
Crystal structure of an engineered protein that forms nanotubes with tunable diameters
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562, ZINC ION
Authors:Brodin, J.D, Smith, S.J, Tezcan, F.A.
Deposit date:2015-06-03
Release date:2016-06-08
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Designed, Helical Protein Nanotubes with Tunable Diameters from a Single Building Block.
To be Published
5CMQ
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BU of 5cmq by Molmil
Crystal Structure of Zn-bound Human H-Ferritin variant 122H-delta C-star
Descriptor: Ferritin heavy chain, ZINC ION
Authors:Sontz, P.A, Bailey, J.B, Ahn, S, Tezcan, F.A.
Deposit date:2015-07-17
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.935 Å)
Cite:A Metal Organic Framework with Spherical Protein Nodes: Rational Chemical Design of 3D Protein Crystals.
J.Am.Chem.Soc., 137, 2015
5CMR
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BU of 5cmr by Molmil
Crystal Structure of Linker-Mediated Zn-bound Human H-Ferritin variant 122H-delta C-star
Descriptor: Ferritin heavy chain, N,N'-dihydroxybenzene-1,4-dicarboxamide, SODIUM ION, ...
Authors:Sontz, P.A, Bailey, J.B, Ahn, S, Tezcan, F.A.
Deposit date:2015-07-17
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.792 Å)
Cite:A Metal Organic Framework with Spherical Protein Nodes: Rational Chemical Design of 3D Protein Crystals.
J.Am.Chem.Soc., 137, 2015
5CX1
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BU of 5cx1 by Molmil
Nitrogenase molybdenum-iron protein beta-K400E mutant
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(8)-S(7) CLUSTER, ...
Authors:Owens, C.P, Luca, M.A, Tezcan, F.A.
Deposit date:2015-07-28
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7476 Å)
Cite:Evidence for Functionally Relevant Encounter Complexes in Nitrogenase Catalysis.
J.Am.Chem.Soc., 137, 2015
6O7S
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BU of 6o7s by Molmil
Nitrogenase MoFeP mutant S188A from Azotobacter vinelandii in the indigo carmine oxidized state
Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(6)-S(7) CLUSTER, ...
Authors:Rutledge, H.L, Tezcan, F.A.
Deposit date:2019-03-08
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Redox-Dependent Metastability of the Nitrogenase P-Cluster.
J.Am.Chem.Soc., 141, 2019

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