8AGO
| BK Polyomavirus VP1 mutant E73Q | Descriptor: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | Authors: | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | Deposit date: | 2022-07-20 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.853 Å) | Cite: | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus. Cell Rep, 42, 2023
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6ZRZ
| Crystal structure of 5-dimethylallyl tryptophan synthase from Streptomyces coelicolor in complex with DMASPP and Trp | Descriptor: | DMATS type aromatic prenyltransferase, S-(3-methylbut-2-en-1-yl) trihydrogen thiodiphosphate, TRYPTOPHAN | Authors: | Ostertag, E, Broger, K, Stehle, T, Zocher, G. | Deposit date: | 2020-07-15 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.696 Å) | Cite: | Reprogramming Substrate and Catalytic Promiscuity of Tryptophan Prenyltransferases. J.Mol.Biol., 433, 2020
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6ZS0
| Crystal structure of 5-dimethylallyltryptophan synthase from Streptomyces coelicolor | Descriptor: | DI(HYDROXYETHYL)ETHER, DMATS type aromatic prenyltransferase | Authors: | Ostertag, E, Broger, K, Stehle, T, Zocher, G. | Deposit date: | 2020-07-15 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Reprogramming Substrate and Catalytic Promiscuity of Tryptophan Prenyltransferases. J.Mol.Biol., 433, 2020
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6ZRY
| 6-dimethylallyl tryptophan synthase | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, DMATS type aromatic prenyltransferase, ... | Authors: | Ostertag, E, Stehle, T, Zocher, G. | Deposit date: | 2020-07-15 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.652 Å) | Cite: | Reprogramming Substrate and Catalytic Promiscuity of Tryptophan Prenyltransferases. J.Mol.Biol., 433, 2020
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3T8E
| Crystal structure of CerJ from Streptomyces tendae soaked with CerviK | Descriptor: | ACETATE ION, CerJ | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | Deposit date: | 2011-08-01 | Release date: | 2011-12-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat.Chem.Biol., 8, 2011
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6ZLZ
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6ZML
| CryoEM Structure of Merkel Cell Polyomavirus Virus-like Particle | Descriptor: | Capsid protein VP1 | Authors: | Bayer, N.J, Januliene, D, Stehle, T, Moeller, A, Blaum, B.S. | Deposit date: | 2020-07-03 | Release date: | 2020-08-05 | Last modified: | 2020-10-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor. J.Virol., 94, 2020
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3T5Y
| Crystal structure of CerJ from Streptomyces tendae - malonic acid covalently linked to the catalytic Cystein C116 | Descriptor: | ACETATE ION, CerJ | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | Deposit date: | 2011-07-28 | Release date: | 2011-12-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat.Chem.Biol., 8, 2011
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8B5B
| Human BRD4 bromdomain 1 in complex with a H4 peptide containing acetyl lysine and ApmTri (H4K5acK8ApmTri) | Descriptor: | Bromodomain-containing protein 4, DI(HYDROXYETHYL)ETHER, H4K5acK8ApmTri | Authors: | Braun, M.B, Bartlick, N, Stehle, T. | Deposit date: | 2022-09-22 | Release date: | 2023-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family. Angew.Chem.Int.Ed.Engl., 62, 2023
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8B5C
| Human BRD4 bromdomain 1 in complex with a H4 peptide containing ApmTri (H4K5/8ApmTri) | Descriptor: | Bromodomain-containing protein 4, H4K5/8ApmTri | Authors: | Braun, M.B, Bartlick, N, Stehle, T. | Deposit date: | 2022-09-22 | Release date: | 2023-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family. Angew.Chem.Int.Ed.Engl., 62, 2023
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8B5A
| Human BRD3 bromodomain 2 in complex with a H4 peptide containing ApmTri (H4K20ApmTri) | Descriptor: | Bromodomain-containing protein 3, H4K20ApmTri | Authors: | Braun, M.B, Bartlick, N, Stehle, T. | Deposit date: | 2022-09-22 | Release date: | 2023-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family. Angew.Chem.Int.Ed.Engl., 62, 2023
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3T6S
| Crystal structure of CerJ from Streptomyces tendae in Complex with CoA | Descriptor: | COENZYME A, CerJ | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | Deposit date: | 2011-07-29 | Release date: | 2011-12-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat.Chem.Biol., 8, 2011
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5EMI
| N-acetylmuramoyl-L-alanine amidase AmiC2 of Nostoc punctiforme | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell wall hydrolase/autolysin, ... | Authors: | Buettner, F.M, Stehle, T. | Deposit date: | 2015-11-06 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Enabling cell-cell communication via nanopore formation: structure, function and localization of the unique cell wall amidase AmiC2 of Nostoc punctiforme. Febs J., 283, 2016
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3EXW
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4WAD
| Crystal Structure of TarM with UDP-GlcNAc | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Glycosyl transferase, ... | Authors: | Koc, C, Stehle, T, Xia, G, Peschel, A. | Deposit date: | 2014-08-29 | Release date: | 2015-02-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid. J.Biol.Chem., 290, 2015
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4L68
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4X21
| The MAP kinase JNK3 as target for halogen bonding | Descriptor: | CHLORIDE ION, Mitogen-activated protein kinase 10, N-ethyl-4-{[4-(1H-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide | Authors: | Lange, A, Buettner, F.M, Guenther, M.B, Zimmermann, M.O, Hennig, S, Laufer, S.A, Stehle, T, Boeckler, F. | Deposit date: | 2014-11-25 | Release date: | 2015-11-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond. J.Am.Chem.Soc., 137, 2015
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4EE6
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4KC5
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6H1J
| TarP native | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Probable ss-1,3-N-acetylglucosaminyltransferase | Authors: | Guo, Y, Stehle, T. | Deposit date: | 2018-07-11 | Release date: | 2018-09-26 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity. Nature, 563, 2018
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3TW5
| Crystal structure of the GP42 transglutaminase from Phytophthora sojae | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Transglutaminase elicitor | Authors: | Reiss, K, Kirchner, E, Zocher, G, Stehle, T. | Deposit date: | 2011-09-21 | Release date: | 2011-10-12 | Last modified: | 2020-10-21 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural and Phylogenetic Analyses of the GP42 Transglutaminase from Phytophthora sojae Reveal an Evolutionary Relationship between Oomycetes and Marine Vibrio Bacteria. J.Biol.Chem., 286, 2011
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3BWR
| SV40 VP1 pentamer in complex with GM1 oligosaccharide | Descriptor: | 1,2-ETHANEDIOL, Capsid protein VP1, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Neu, U, Stehle, T. | Deposit date: | 2008-01-10 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis of GM1 ganglioside recognition by simian virus 40. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BWQ
| Structure of free SV40 VP1 pentamer | Descriptor: | Capsid protein VP1 | Authors: | Neu, U, Stehle, T. | Deposit date: | 2008-01-10 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of GM1 ganglioside recognition by simian virus 40. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3S7X
| Unassembled Washington University Polyomavirus VP1 Pentamer R198K Mutant | Descriptor: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1, ... | Authors: | Neu, U, Wang, J, Stehle, T. | Deposit date: | 2011-05-27 | Release date: | 2011-06-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of the major capsid proteins of the human KI and WU polyomaviruses. J.Virol., 85, 2011
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4Q4W
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