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PDB: 66 results

5AO0
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BU of 5ao0 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 41-583) bound to ddGTP
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ...
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.731 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO4
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Crystal structure of in vitro phosphorylated human SAMHD1 (amino acid residues 115-626) bound to GTP
Descriptor: DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, GUANOSINE-5'-TRIPHOSPHATE
Authors:Arnold, L.H, Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
2BF0
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BU of 2bf0 by Molmil
crystal structure of the rpr of pcf11
Descriptor: CALCIUM ION, PCF11
Authors:Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A.
Deposit date:2004-12-02
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd.
Nat.Struct.Mol.Biol., 12, 2005
8QXO
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BU of 8qxo by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXN
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BU of 8qxn by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State IV - Depleted relaxed
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXL
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BU of 8qxl by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXK
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BU of 8qxk by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State I - Tense
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXM
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BU of 8qxm by Molmil
Cryo-EM structure of tetrameric human SAMHD1 State III - Relaxed
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
8QXJ
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BU of 8qxj by Molmil
Cryo-EM structure of tetrameric human SAMHD1 with dApNHpp
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ...
Authors:Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A.
Deposit date:2023-10-24
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
2ATW
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BU of 2atw by Molmil
Structure of a Mycobacterium tuberculosis NusA-RNA complex
Descriptor: Transcription elongation protein nusA, ribosomal RNA (5'- AGAACUCAAUAG -3')
Authors:Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A.
Deposit date:2005-08-26
Release date:2005-10-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
1L3G
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BU of 1l3g by Molmil
NMR Structure of the DNA-binding Domain of Cell Cycle Protein, Mbp1(2-124) from Saccharomyces cerevisiae
Descriptor: TRANSCRIPTION FACTOR Mbp1
Authors:Nair, M, McIntosh, P.B, Frenkiel, T.A, Kelly, G, Taylor, I.A, Smerdon, S.J, Lane, A.N.
Deposit date:2002-02-27
Release date:2003-02-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR Structure of the DNA-Binding Domain of the Cell Cycle Protein Mbp1 from Saccharomyces cerevisiae
Biochemistry, 42, 2003
1O9S
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BU of 1o9s by Molmil
Crystal structure of a ternary complex of the human histone methyltransferase SET7/9
Descriptor: GENE FRAGMENT FOR HISTONE H3, HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, ...
Authors:Xiao, B, Jing, C, Wilson, J.R, Walker, P.A, Vasisht, N, Kelly, G, Howell, S, Taylor, I.A, Blackburn, G.M, Gamblin, S.J.
Deposit date:2002-12-18
Release date:2003-02-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9
Nature, 421, 2003
1SML
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BU of 1sml by Molmil
METALLO BETA LACTAMASE L1 FROM STENOTROPHOMONAS MALTOPHILIA
Descriptor: PROTEIN (PENICILLINASE), ZINC ION
Authors:Ullah, J.H, Walsh, T.R, Taylor, I.A, Emery, D.C, Verma, C.S, Gamblin, S.J, Spencer, J.
Deposit date:1998-09-22
Release date:1999-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 A resolution.
J.Mol.Biol., 284, 1998
1SW6
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BU of 1sw6 by Molmil
S. CEREVISIAE SWI6 ANKYRIN-REPEAT FRAGMENT
Descriptor: REGULATORY PROTEIN SWI6
Authors:Foord, R, Taylor, I.A, Sedgwick, S.G, Smerdon, S.J.
Deposit date:1998-09-28
Release date:1999-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structural analysis of the yeast cell cycle regulator Swi6 reveals variations of the ankyrin fold and has implications for Swi6 function.
Nat.Struct.Biol., 6, 1999
1U7K
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BU of 1u7k by Molmil
Structure of a hexameric N-terminal domain from murine leukemia virus capsid
Descriptor: Gag polyprotein
Authors:Mortuza, G.B, Haire, L.F, Stevens, A, Smerdon, S.J, Stoye, J.P, Taylor, I.A.
Deposit date:2004-08-04
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:High-resolution structure of a retroviral capsid hexameric amino-terminal domain.
Nature, 431, 2004
8COO
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BU of 8coo by Molmil
Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3')
Authors:Nicastro, G, Abis, G, Taylor, I.A, Ramos, A.
Deposit date:2023-02-28
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers.
Nucleic Acids Res., 51, 2023
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