3J05
| Three-dimensional structure of Dengue virus serotype 1 complexed with HMAb 14c10 Fab | Descriptor: | envelope protein | Authors: | Teoh, E.P, Kukkaro, P, Teo, E.W, Lim, A, Tan, T.T, Shi, P.Y, Yip, A, Schul, W, Leo, Y.S, Chan, S.H, Smith, K.G.C, Ooi, E.E, Kemeny, D.M, Ng, G, Ng, M.L, Alonso, S, Fisher, D, Hanson, B, Lok, S.M, MacAry, P.A. | Deposit date: | 2011-04-01 | Release date: | 2012-07-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | The structural basis for serotype-specific neutralization of dengue virus by a human antibody. Sci Transl Med, 4, 2012
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6LCQ
| Crystal structure of rice defensin OsAFP1 | Descriptor: | Defensin-like protein CAL1, PHOSPHATE ION | Authors: | Ochiai, A, Ogawa, K, Fukuda, M, Suzuki, M, Ito, K, Tanaka, T, Sagehashi, Y, Taniguchi, M. | Deposit date: | 2019-11-19 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Crystal structure of rice defensin OsAFP1 and molecular insight into lipid-binding. J.Biosci.Bioeng., 130, 2020
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3K4M
| Pyranose 2-oxidase Y456W mutant in complex with 2FG | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase. Febs J., 277, 2010
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1GLV
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3GRH
| Crystal structure of escherichia coli ybhc | Descriptor: | Acyl-CoA thioester hydrolase ybgC | Authors: | Eklof, J.M, Tan, T.C, Divne, C, Brumer, H. | Deposit date: | 2009-03-25 | Release date: | 2009-04-07 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The crystal structure of the outer membrane lipoprotein YbhC from Escherichia coli sheds new light on the phylogeny of carbohydrate esterase family 8. Proteins, 76, 2009
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3K4C
| Pyranose 2-oxidase H167A/T169G mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ... | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A conserved active-site threonine is important for both sugar and flavin oxidations of pyranose 2-oxidase. J.Biol.Chem., 285, 2010
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3K4J
| Pyranose 2-oxidase H450Q mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase. Febs J., 277, 2010
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3K4B
| Pyranose 2-oxidase T169S mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A conserved active-site threonine is important for both sugar and flavin oxidations of pyranose 2-oxidase. J.Biol.Chem., 285, 2010
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3K4K
| Pyranose 2-oxidase F454N mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase. Febs J., 277, 2010
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3K4L
| Pyranose 2-oxidase F454N mutant in complex with 2FG | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase. Febs J., 277, 2010
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3JXS
| Crystal structure of XG34, an evolved xyloglucan binding CBM | Descriptor: | ACETATE ION, CALCIUM ION, Xylanase | Authors: | Divne, C, Tan, T.-C, Brumer, H, Gullfot, F. | Deposit date: | 2009-09-21 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of XG-34, an evolved xyloglucan-specific carbohydrate-binding module. Proteins, 78, 2009
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3LSH
| Pyranose 2-oxidase T169A, monoclinic | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase | Authors: | Divne, C, Tan, T.C, Spadiut, O. | Deposit date: | 2010-02-12 | Release date: | 2010-08-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | H-bonding and positive charge at the N5/O4 locus are critical for covalent flavin attachment in trametes pyranose 2-oxidase. J.Mol.Biol., 402, 2010
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6ODB
| Crystal structure of HDAC8 in complex with compound 3 | Descriptor: | GLYCEROL, Histone deacetylase 8, N-{2-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]phenyl}-2-phenoxybenzamide, ... | Authors: | Zheng, X, Conti, C, Caravella, J, Zablocki, M.-M, Bair, K, Barczak, N, Han, B, Lancia Jr, D, Liu, C, Martin, M, Ng, P.Y, Rudnitskaya, A, Thomason, J.J, Garcia-Dancey, R, Hardy, C, Lahdenranta, J, Leng, C, Li, P, Pardo, E, Saldahna, A, Tan, T, Toms, A.V, Yao, L, Zhang, C. | Deposit date: | 2019-03-26 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-based Discovery of Novel N-(E)-N-Hydroxy-3-(2-(2-oxoimidazolidin-1-yl)phenyl)acrylamides as Potent and Selective HDAC8 inhibitors To Be Published
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6ODC
| Crystal structure of HDAC8 in complex with compound 30 | Descriptor: | (2E)-3-[2-(3-cyclopentyl-5,5-dimethyl-2-oxoimidazolidin-1-yl)phenyl]-N-hydroxyprop-2-enamide, 1,2-ETHANEDIOL, Histone deacetylase 8, ... | Authors: | Zheng, X, Conti, C, Caravella, J, Zablocki, M.-M, Bair, K, Barczak, N, Han, B, Lancia Jr, D, Liu, C, Martin, M, Ng, P.Y, Rudnitskaya, A, Thomason, J.J, Garcia-Dancey, R, Hardy, C, Lahdenranta, J, Leng, C, Li, P, Pardo, E, Saldahna, A, Tan, T, Toms, A.V, Yao, L, Zhang, C. | Deposit date: | 2019-03-26 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based Discovery of Novel N-(E)-N-Hydroxy-3-(2-(2-oxoimidazolidin-1-yl)phenyl)acrylamides as Potent and Selective HDAC8 inhibitors To Be Published
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2E1X
| NMR structure of the HIV-2 nucleocapsid protein | Descriptor: | Gag-Pol polyprotein (Pr160Gag-Pol), ZINC ION | Authors: | Matsui, T, Kodera, Y, Miyauchi, E, Tanaka, H, Endoh, H, Komatsu, H, Tanaka, T, Kohno, T, Maeda, T. | Deposit date: | 2006-11-03 | Release date: | 2007-06-05 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structural role of the secondary active domain of HIV-2 NCp8 in multi-functionality Biochem.Biophys.Res.Commun., 358, 2007
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2EC7
| Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein | Descriptor: | Gag polyprotein (Pr55Gag), ZINC ION | Authors: | Matsui, T, Kodera, Y, Tanaka, T, Endoh, H, Tanaka, H, Miyauchi, E, Komatsu, H, Kohno, T, Maeda, T. | Deposit date: | 2007-02-10 | Release date: | 2008-02-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The RNA recognition mechanism of human immunodeficiency virus (HIV) type 2 NCp8 is different from that of HIV-1 NCp7 Biochemistry, 48, 2009
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6ODA
| Crystal structure of HDAC8 in complex with compound 2 | Descriptor: | Histone deacetylase 8, N-{2-[3-(hydroxyamino)-3-oxopropyl]phenyl}-3-(trifluoromethyl)benzamide, POTASSIUM ION, ... | Authors: | Zheng, X, Conti, C, Caravella, J, Zablocki, M.-M, Bair, K, Barczak, N, Han, B, Lancia Jr, D, Liu, C, Martin, M, Ng, P.Y, Rudnitskaya, A, Thomason, J.J, Garcia-Dancey, R, Hardy, C, Lahdenranta, J, Leng, C, Li, P, Pardo, E, Saldahna, A, Tan, T, Toms, A.V, Yao, L, Zhang, C. | Deposit date: | 2019-03-26 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Structure-based Discovery of Novel N-(E)-N-Hydroxy-3-(2-(2-oxoimidazolidin-1-yl)phenyl)acrylamides as Potent and Selective HDAC8 inhibitors To Be Published
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3K4N
| Pyranose 2-oxidase F454A/S455A/Y456A mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase. Febs J., 277, 2010
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4CAU
| THREE-DIMENSIONAL STRUCTURE OF DENGUE VIRUS SEROTYPE 1 COMPLEXED WITH 2 HMAB 14C10 FAB | Descriptor: | ENVELOPE PROTEIN E, FAB 14C10 | Authors: | Teoh, E.P, Kukkaro, P, Teo, E.W, Lim, A.P, Tan, T.T, Yip, A, Schul, W, Aung, M, Kostyuchenko, V.A, Leo, Y.S, Chan, S.H, Smith, K.G, Chan, A.H, Zou, G, Ooi, E.E, Kemeny, D.M, Tan, G.K, Ng, J.K, Ng, M.L, Alonso, S, Fisher, D, Shi, P.Y, Hanson, B.J, Lok, S.M, Macary, P.A. | Deposit date: | 2013-10-09 | Release date: | 2013-10-16 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | The Structural Basis for Serotype-Specific Neutralization of Dengue Virus by a Human Antibody. Sci.Trans.Med, 4, 2012
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5H37
| Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ... | Authors: | Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M. | Deposit date: | 2016-10-20 | Release date: | 2016-11-30 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Neutralization mechanism of a highly potent antibody against Zika virus Nat Commun, 7, 2016
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4MIG
| Pyranose 2-oxidase from Phanerochaete chrysosporium, recombinant wild type | Descriptor: | 3-deoxy-3-fluoro-beta-D-glucopyranose, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Hassan, N, Tan, T.C, Spadiut, O, Pisanelli, I, Fusco, L, Haltrich, D, Peterbauer, C, Divne, C. | Deposit date: | 2013-08-31 | Release date: | 2013-12-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of Phanerochaete chrysosporium pyranose 2-oxidase suggest that the N-terminus acts as a propeptide that assists in homotetramer assembly. FEBS Open Bio, 3, 2013
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4MIH
| Pyranose 2-oxidase from Phanerochaete chrysosporium, recombinant H158A mutant | Descriptor: | 3-deoxy-3-fluoro-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose 2-oxidase | Authors: | Hassan, N, Tan, T.C, Spadiut, O, Pisanelli, I, Fusco, L, Haltrich, D, Peterbauer, C, Divne, C. | Deposit date: | 2013-08-31 | Release date: | 2013-12-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Phanerochaete chrysosporium pyranose 2-oxidase suggest that the N-terminus acts as a propeptide that assists in homotetramer assembly. FEBS Open Bio, 3, 2013
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4MIF
| Pyranose 2-oxidase from Phanerochaete chrysosporium, wild type from natural source | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, MAGNESIUM ION, Pyranose 2-oxidase | Authors: | Hassan, N, Tan, T.C, Spadiut, O, Pisanelli, I, Fusco, L, Haltrich, D, Peterbauer, C, Divne, C. | Deposit date: | 2013-08-31 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of Phanerochaete chrysosporium pyranose 2-oxidase suggest that the N-terminus acts as a propeptide that assists in homotetramer assembly. FEBS Open Bio, 3, 2013
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2QHD
| Crystal structure of ecarpholin S (ser49-PLA2) complexed with fatty acid | Descriptor: | LAURIC ACID, Phospholipase A2 | Authors: | Zhou, X, Tan, T.C, Valiyaveettil, S, Go, M.L, Kini, R.M, Sivaraman, J. | Deposit date: | 2007-07-02 | Release date: | 2007-10-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom Biophys.J., 95, 2008
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4PTW
| Halothermothrix orenii beta-glucosidase A, 2-deoxy-2-fluoro-glucose complex | Descriptor: | 2-deoxy-2-fluoro-alpha-D-glucopyranose, Glycoside hydrolase family 1, TETRAETHYLENE GLYCOL | Authors: | Hassan, N, Nguyen, T.H, Kori, L.D, Patel, B.K.C, Haltrich, D, Divne, C, Tan, T.C. | Deposit date: | 2014-03-11 | Release date: | 2014-09-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biochemical and structural characterization of a thermostable beta-glucosidase from Halothermothrix orenii for galacto-oligosaccharide synthesis. Appl.Microbiol.Biotechnol., 99, 2015
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