3W6I
| Crystal structure of 19F probe-labeled hCAI | Descriptor: | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, Carbonic anhydrase 1, ZINC ION | Authors: | Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I. | Deposit date: | 2013-02-14 | Release date: | 2013-03-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.693 Å) | Cite: | Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR To be published
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3QAR
| Crystal structure of PI3K-gamma in complex with triazine-benzimidazole 32 | Descriptor: | 1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-pyrazol-3-yl)-1H-benzimidazol-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | Authors: | Whittington, D.A, Tang, J, Yakowec, P. | Deposit date: | 2011-01-11 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of triazine-benzimidazoles as selective inhibitors of mTOR. Bioorg.Med.Chem.Lett., 21, 2011
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2NAR
| Solution structure of AVR3a_60-147 from Phytophthora infestans | Descriptor: | Effector protein Avr3a | Authors: | Matena, A, Bayer, P, Zhukov, I, Stanek, J, Kozminski, W, van West, P, Wawra, S. | Deposit date: | 2016-01-08 | Release date: | 2017-01-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The RxLR Motif of the Host Targeting Effector AVR3a ofPhytophthora infestansIs Cleaved before Secretion. Plant Cell, 29, 2017
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2MOQ
| Solution Structure and Molecular determinants of Hemoglobin Binding of the first NEAT Domain of IsdB in Staphylococcus aureus | Descriptor: | Iron-regulated surface determinant protein B | Authors: | Fonner, B.A, Tripet, B.P, Eilers, B.J, Stanisich, J, Sullivan-Springhetti, R.K, Moore, R, Lui, M, Lei, B, Copie, V. | Deposit date: | 2014-04-29 | Release date: | 2014-07-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure and Molecular Determinants of Hemoglobin Binding of the First NEAT Domain of IsdB in Staphylococcus aureus. Biochemistry, 53, 2014
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6HYK
| NMR solution structure of the C/D box snoRNA U14 | Descriptor: | RNA (31-MER) | Authors: | Chagot, M.E, Quinternet, M, Rothe, B, Charpentier, B, Coutant, J, Manival, X, Lebars, I. | Deposit date: | 2018-10-22 | Release date: | 2019-04-24 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | The yeast C/D box snoRNA U14 adopts a "weak" K-turn like conformation recognized by the Snu13 core protein in solution. Biochimie, 164, 2019
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1FB7
| CRYSTAL STRUCTURE OF AN IN VIVO HIV-1 PROTEASE MUTANT IN COMPLEX WITH SAQUINAVIR: INSIGHTS INTO THE MECHANISMS OF DRUG RESISTANCE | Descriptor: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, HIV-1 PROTEASE | Authors: | Hong, L, Zhang, X.C, Hartsuck, J.A, Tang, J. | Deposit date: | 2000-07-14 | Release date: | 2000-12-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: insights into the mechanisms of drug resistance. Protein Sci., 9, 2000
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1FKN
| Structure of Beta-Secretase Complexed with Inhibitor | Descriptor: | MEMAPSIN 2, inhibitor | Authors: | Hong, L, Koelsch, G, Lin, X, Wu, S, Terzyan, S, Ghosh, A, Zhang, X.C, Tang, J. | Deposit date: | 2000-08-09 | Release date: | 2000-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science, 290, 2000
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2M3W
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2OYV
| Neurotensin in DPC micelles | Descriptor: | neurotensin | Authors: | Monti, J.P, Coutant, J, Curmi, P.A. | Deposit date: | 2007-02-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of Neurotensin in Membrane-Mimetic Environments: Molecular Basis for Neurotensin Receptor Recognition. Biochemistry, 46, 2007
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2OYW
| Neurotensin in TFE:H2O (80:20) | Descriptor: | neurotensin | Authors: | Monti, J.P, Coutant, J, Curmi, P.A. | Deposit date: | 2007-02-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of Neurotensin in Membrane-Mimetic Environments: Molecular Basis for Neurotensin Receptor Recognition. Biochemistry, 46, 2007
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4BZD
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4NBZ
| Crystal Structure of TcdA-A1 Bound to A26.8 VHH | Descriptor: | A26.8 VHH, TcdA | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | Deposit date: | 2013-10-23 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4NBY
| Crystal Structure of TcdA-A2 Bound to Two Molecules of A20.1 VHH | Descriptor: | A20.1 VHH, Cell wall-binding repeat protein | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E, Klassen, J.S, Ng, K.K.S. | Deposit date: | 2013-10-23 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4NC1
| Crystal Structure of TcdA-A2 Bound to A20.1 VHH and A26.8 VHH | Descriptor: | A20.1 VHH, A26.8 VHH, Cell wall-binding repeat protein | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | Deposit date: | 2013-10-23 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4NC0
| Crystal Structure of TcdA-A2 Bound to A26.8 VHH | Descriptor: | A26.8 VHH, Cell wall-binding repeat protein | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | Deposit date: | 2013-10-23 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4NC2
| Crystal structure of TcdB-B1 bound to B39 VHH | Descriptor: | B39 VHH, Toxin B | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | Deposit date: | 2013-10-23 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4Q57
| Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Song, J.-G, Kostan, J, Grishkovskaya, I, Djinovic-Carugo, K. | Deposit date: | 2014-04-16 | Release date: | 2014-07-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex To be Published
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4NBX
| Crystal Structure of Clostridium difficile Toxin A fragment TcdA-A1 Bound to A20.1 VHH | Descriptor: | A20.1 VHH, TcdA | Authors: | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | Deposit date: | 2013-10-23 | Release date: | 2013-12-11 | Last modified: | 2014-02-12 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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4Q58
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4Q59
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