7ZOB
 
 | | Metagenomic cytidine deaminase Cdd | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Metagenomic cytidine deaminase Cdd, SULFATE ION, ... | | 著者 | Tamulaitiene, G, Urbeliene, N, Meskys, R. | | 登録日 | 2022-04-25 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Cytidine deaminases catalyze the conversion of N ( S , O ) 4 -substituted pyrimidine nucleosides.
Sci Adv, 9, 2023
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2IXS
 | | Structure of SdaI restriction endonuclease | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SDAI RESTRICTION ENDONUCLEASE, ... | | 著者 | Tamulaitiene, G, Jakubauskas, A, Urbanke, C, Huber, R, Grazulis, S, Siksnys, V. | | 登録日 | 2006-07-11 | | 公開日 | 2006-09-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of the Rare-Cutting Restriction Enzyme Sdai Reveals Unexpected Domain Architecture
Structure, 14, 2006
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4QDL
 | | Crystal structure of E.coli Cas1-Cas2 complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2 | | 著者 | Tamulaitiene, G, Sinkunas, T, Silanskas, A, Gasiunas, G, Grazulis, S, Siksnys, V. | | 登録日 | 2014-05-14 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of E.coli Cas1-Cas2 complex
To be Published
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4ZSF
 | | Crystal structure of pre-specific restriction endonuclease BsaWI-DNA complex | | 分子名称: | BsaWI endonuclease, CALCIUM ION, DNA, ... | | 著者 | Tamulaitiene, G, Rutkauskas, M, Grazulis, S, Siksnys, V. | | 登録日 | 2015-05-13 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI.
Nucleic Acids Res., 43, 2015
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5O63
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4RCT
 | | Crystal structure of R-protein of NgoAVII restriction endonuclease | | 分子名称: | Restriction endonuclease R.NgoVII | | 著者 | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | | 登録日 | 2014-09-17 | | 公開日 | 2014-12-24 | | 最終更新日 | 2014-12-31 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Nucleic Acids Res., 42, 2014
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4RD5
 | | Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA | | 分子名称: | DNA (5'-D(*CP*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*GP*G)-3'), Restriction endonuclease R.NgoVII | | 著者 | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | | 登録日 | 2014-09-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Nucleic Acids Res., 42, 2014
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4RDM
 | | Crystal structure of R.NgoAVII restriction endonuclease B3 domain with cognate DNA | | 分子名称: | DNA (5'-D(*CP*CP*TP*AP*AP*GP*CP*GP*GP*CP*AP*AP*TP*CP*C)-3)', DNA (5'-D(*GP*GP*GP*AP*TP*TP*GP*CP*CP*GP*CP*TP*TP*AP*G)-3)', Restriction endonuclease R.NgoVII, ... | | 著者 | Tamulaitiene, G, Silanskas, A, Grazulis, S, Zaremba, M, Siksnys, V. | | 登録日 | 2014-09-19 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Nucleic Acids Res., 42, 2014
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7BB5
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8PHJ
 | | cA4-bound Cami1 in complex with 70S ribosome | | 分子名称: | 16S rRNA, 23S rRNA (2862-MER), 5S rRNA, ... | | 著者 | Tamulaitiene, G, Mogila, I, Sasnauskas, G, Tamulaitis, G. | | 登録日 | 2023-06-20 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling.
Science, 382, 2023
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8PHB
 | | Crystal structure of apo Cami1 | | 分子名称: | CRISPR-associated protein, APE2256 family | | 著者 | Tamulaitiene, G, Tamulaitis, G, Mogila, I, Keda, K. | | 登録日 | 2023-06-19 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling.
Science, 382, 2023
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8BTO
 | | Helical structure of BcThsA in complex with 1''-3'gcADPR | | 分子名称: | (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, NAD(+) hydrolase ThsA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Tamulaitiene, G, Sasnauskas, G, Sabonis, D. | | 登録日 | 2022-11-29 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Activation of Thoeris antiviral system via SIR2 effector filament assembly.
Nature, 627, 2024
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8BTP
 | | Helical structure of BcThsA in complex with 1''-3'gc(etheno)ADPR | | 分子名称: | (1S,3S,4R,5R,7R,15R,16S,17R)-5-imidazo[2,1-f]purin-3-yl-10,12-bis(oxidanyl)-10,12-bis(oxidanylidene)-2,6,9,11,13,18-hexaoxa-10$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{3,7}]octadecane-4,16,17-triol, ETHENO-NAD, NAD(+) hydrolase ThsA | | 著者 | Tamulaitiene, G, Sasnauskas, G, Sabonis, D. | | 登録日 | 2022-11-29 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Activation of Thoeris antiviral system via SIR2 effector filament assembly.
Nature, 627, 2024
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8BTN
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5DWB
 | | Crystal structure of specific restriction endonuclease AgeI-DNA complex | | 分子名称: | DNA (5'-D(*TP*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*GP*A*)-3'), Type-2 restriction enzyme AgeI | | 著者 | Tamulaitiene, G, Jovaisaite, V, Grazulis, S, Siksnys, V. | | 登録日 | 2015-09-22 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA.
Nucleic Acids Res., 45, 2017
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5DWA
 | | Crystal structure of pre-specific restriction endonuclease AgeI-DNA complex | | 分子名称: | DNA (5'-D(*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*G*)-3'), Type-2 restriction enzyme AgeI | | 著者 | Tamulaitiene, G, Jovaisaite, V, Grazulis, S, Siksnys, V. | | 登録日 | 2015-09-22 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA.
Nucleic Acids Res., 45, 2017
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5DWC
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7AER
 | | Rebuilt and re-refined PDB entry 5yep: tri-AMPylated Shewanella oneidensis HEPN toxin in complex with MNT antitoxin | | 分子名称: | ADENOSINE MONOPHOSPHATE, Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | | 著者 | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | | 登録日 | 2020-09-18 | | 公開日 | 2020-12-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
Mol.Cell, 80, 2020
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7AE9
 | | Crystal structure of mono-AMPylated HEPN(R46E) toxin in complex with MNT antitoxin | | 分子名称: | 2',3'-DIDEOXYADENOSINE-5'-MONOPHOSPHATE, HEPN toxin, MNT ANTITOXIN | | 著者 | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | | 登録日 | 2020-09-17 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
Mol.Cell, 80, 2020
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7AE8
 | | Crystal structure of HEPN(R102A) toxin | | 分子名称: | ACETATE ION, HEPN toxin | | 著者 | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | | 登録日 | 2020-09-17 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
Mol.Cell, 80, 2020
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7AE2
 | | Crystal structure of HEPN(H107A-Y109F) toxin in complex with MNT antitoxin | | 分子名称: | HEPN toxin, MNT ANTITOXIN | | 著者 | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | | 登録日 | 2020-09-17 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
Mol.Cell, 80, 2020
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7AE6
 | | Crystal structure of di-AMPylated HEPN(R102A) toxin | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, HEPN toxin | | 著者 | Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. | | 登録日 | 2020-09-17 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
Mol.Cell, 80, 2020
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6FJW
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6EKO
 | | Crystal structure of Type IIP restriction endonuclease PfoI with cognate DNA | | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*CP*TP*CP*CP*CP*GP*GP*AP*GP*CP*GP*T)-3'), Restriction endonuclease PfoI | | 著者 | Tamulaitiene, G, Manakova, E, Jovaisaite, V, Grazulis, S, Siksnys, V. | | 登録日 | 2017-09-26 | | 公開日 | 2018-10-10 | | 最終更新日 | 2019-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.284 Å) | | 主引用文献 | Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family.
Nucleic Acids Res., 47, 2019
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6EK1
 | | Crystal structure of Type IIP restriction endonuclease PfoI | | 分子名称: | 1,2-ETHANEDIOL, restriction endonuclease PfoI | | 著者 | Tamulaitiene, G, Manakova, E, Jovaisaite, V, Grazulis, S, Siksnys, V. | | 登録日 | 2017-09-25 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family.
Nucleic Acids Res., 47, 2019
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