4OUA
 
 | | Coexistent single-crystal structure of latent and active mushroom tyrosinase (abPPO4) mediated by a hexatungstotellurate(VI) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-tungstotellurate(VI), COPPER (I) ION, ... | | 著者 | St.Mauracher, G, Molitor, C, Al-Oweini, R, Kortz, U, Rompel, A. | | 登録日 | 2014-02-15 | | 公開日 | 2014-06-25 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.763 Å) | | 主引用文献 | Latent and active abPPO4 mushroom tyrosinase cocrystallized with hexatungstotellurate(VI) in a single crystal.
Acta Crystallogr.,Sect.D, 70, 2014
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4MS2
 | | Structural basis of Ca2+ selectivity of a voltage-gated calcium channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-18 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4MTF
 | | Structural Basis of Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-19 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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3CIR
 | | E. coli Quinol fumarate reductase FrdA T234A mutation | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Tomasiak, T.M, Maklashina, E, Cecchini, G, Iverson, T.M. | | 登録日 | 2008-03-11 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II.
J.Biol.Chem., 283, 2008
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5KMD
 | | Structure of CavAb in complex with amlodipine | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-26 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
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5KLB
 | | Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A) | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-23 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
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5KLS
 | | Structure of CavAb in complex with Br-dihydropyridine derivative UK-59811 | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-25 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.299 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
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5KMH
 | | Structure of CavAb in complex with Br-verapamil | | 分子名称: | (2~{R})-2-(2-bromophenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-27 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
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5KMF
 | | Structure of CavAb in complex with nimodipine | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-26 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
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5KLG
 | | Structure of CavAb(W195Y) in complex with Br-dihydropyridine derivative UK-59811 | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-24 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
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4MTG
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-19 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.296 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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8CQR
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4MVM
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-24 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.1997 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4N0E
 | | Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, SULFATE ION | | 著者 | Thaker, T.M, Preininger, A.M, Sarwar, M, Hamm, H.E, Iverson, T.M. | | 登録日 | 2013-10-01 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Transient Interaction between the Phosphate Binding Loop and Switch I Contributes to the Allosteric Network between Receptor and Nucleotide in G alpha i1.
J.Biol.Chem., 289, 2014
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7AJR
 | | Virtual screening approach leading to the identification of a novel and tractable series of Pseudomonas aeruginosa elastase inhibitors | | 分子名称: | 2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-1,3-dihydroinden-2-yl]ethanoic acid, Keratinase KP2, SULFATE ION, ... | | 著者 | Leiris, S, Davies, D.T, Sprinsky, N, Castandet, J, Behria, L, Bodnarchuk, M.S, Sutton, J.M, Mullins, T.M.G, Jones, M.W, Forrest, A.K, Pallin, T.D, Karunakar, P, Martha, S.K, Parusharamulu, B, Ramula, R, Kotha, V, Pottabathini, N, Pothukanuri, S, Lemonnier, M, Everett, M. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
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5J6F
 | | Crystal structure of DAH7PS-CM complex from Geobacillus sp. with prephenate | | 分子名称: | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, chorismate mutase-isozyme 3, MANGANESE (II) ION, ... | | 著者 | Nazmi, A.R, Othman, M, Lang, E.J.M, Bai, Y, Allison, T.M, Panjkar, S, Arcus, V.L, Parker, E.J. | | 登録日 | 2016-04-04 | | 公開日 | 2016-09-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Interdomain Conformational Changes Provide Allosteric Regulation en Route to Chorismate.
J. Biol. Chem., 291, 2016
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6FM2
 | | CARP domain of mouse cyclase-associated protein 1 (CAP1) bound to ADP-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Kotila, T.M, Kogan, K, Lappalainen, P. | | 登録日 | 2018-01-30 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of actin monomer re-charging by cyclase-associated protein.
Nat Commun, 9, 2018
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4MVS
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CADMIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-24 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.299 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4MTO
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-19 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.402 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4MVQ
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Gilbert, Q.M, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-24 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4N0D
 | | Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GTPgammaS | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, MAGNESIUM ION, ... | | 著者 | Thaker, T.M, Preininger, A.M, Sarwar, M, Hamm, H.E, Iverson, T.M. | | 登録日 | 2013-10-01 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A Transient Interaction between the Phosphate Binding Loop and Switch I Contributes to the Allosteric Network between Receptor and Nucleotide in G alpha i1.
J.Biol.Chem., 289, 2014
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4MVR
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, MANGANESE (II) ION | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Gilbert, Q.M, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-24 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.196 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4MW3
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-24 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2997 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4MVZ
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-24 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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4MVO
 | | Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein | | 著者 | Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2013-09-24 | | 公開日 | 2013-11-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.296 Å) | | 主引用文献 | Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
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